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Clinical Oral Investigations

Erschienen in:

28.01.2021 | Original Article

Tomographic evaluation of direct pulp capping using a novel injectable treated dentin matrix hydrogel: a 2-year randomized controlled clinical trial

verfasst von: Ahmed A. Holiel, Elsayed M. Mahmoud, Wegdan M. Abdel-Fattah

Erschienen in: Clinical Oral Investigations | Ausgabe 7/2021

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Abstract

Objectives

To assess clinically and radiographically the success of pulp capping procedure done in traumatically exposed permanent posterior teeth using a novel injectable treated dentin matrix hydrogel (TDMH), Biodentine, and MTA and to evaluate the formed dentin bridge under the capping materials using CBCT imaging.

Materials and methods

45 patients subjected to accidental traumatic pulp exposures by undergraduate dental students are allocated for this study. For each patient, a pulp capping procedure was done. TDMH was formed of TDM powder and sodium alginate to be injected and then hardened in the defect area. Patients were assigned to 3 groups: TDMH, Biodentine, and MTA, respectively, and returned to the clinic after 3, 6, 12, 18, and 24 months for clinical and radiographic examinations. Tomographic data, including thickness and density of formed dentin bridges, were evaluated at the end of the study period compared to the base line. Pulp sensitivity was evaluated throughout the study period using thermal testing and electric pulp tester.

Results

During the follow-up period, all patients were asymptomatic with no clinical signs and symptoms and revealed no radiographic signs of pathosis. However, tomographic evaluation showed the tested materials to have different levels of impact on formed dentin bridges with TDMH group resulted in significantly superior dentin bridges of a higher radiodensity and thickness than Biodentine and MTA.

Conclusions

TDMH has a greater potential to induce dentin bridge formation than Biodentine and MTA under standardized conditions. Additionally, CBCT imaging was confirmed as a non-invasive and inclusive approach to evaluate the formed dentin bridges after pulp capping procedure.

Clinical relevance

Direct pulp capping can be done successfully with this novel injectable pulp capping material in future clinical applications.

Trial registration

PACTR201901866476410

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Titel: Tomographic evaluation of direct pulp capping using a novel injectable treated dentin matrix hydrogel: a 2-year randomized controlled clinical trial
verfasst von: Ahmed A. Holiel
Elsayed M. Mahmoud
Wegdan M. Abdel-Fattah
Publikationsdatum: 28.01.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 7/2021
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-021-03775-1

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Tomographic evaluation of direct pulp capping using a novel injectable treated dentin matrix hydrogel: a 2-year randomized controlled clinical trial

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

Trial registration

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Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

Trial registration

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