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Lasers in Medical Science

Erschienen in:

01.12.2024 | Review Article

Use of fractionated laser therapy for the treatment of androgenetic alopecia: a systematic review and meta-analysis

verfasst von: Patrick M Jedlowski, Michelle Anthony

Erschienen in: Lasers in Medical Science | Ausgabe 1/2024

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Abstract

Procedural management, including fractionated laser therapy, has been increasingly investigated for the management of androgenetic alopecia (AGA). However, no comprehensive resources exist detailing the efficacy of fractionated laser therapies used for the treatment of AGA. A systematic review investigating fractionated laser use for AGA was performed, separated into each distinct fractionated laser modality. A meta-analysis was performed to examine improvement in hair counts and hair shaft diameter. Fourteen studies were included for systematic review, which identified the use of erbium-glass, thulium, erbium-ytrrium:aluminum garnet (YAG), and carbon dioxide (CO₂) fractionated laser for the treatment of AGA. In the meta-analysis, fractionated laser combination therapy showed significant improvement in hair shaft diameter (2.51, 95% CI 2.37–2.65, I² = 90.54). Fractionated laser monotherapy alone significantly improved hair shaft diameter (2.28 95% CI 2.03–2.52, I² = 91.20%). This effect was durable on subgroup analysis for both erbium-glass (2.36 95% CI 2.01–2.71, I² = 92.05%) and thulium (1.61 95% CI 1.08–2.15, I² = < 0.00%). There was no improvement in hair shaft count for any laser modality. Erbium-glass laser is an effective modality as either monotherapy or combination with topical/injectable therapies to improve hair shaft diameter in AGA.

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Titel: Use of fractionated laser therapy for the treatment of androgenetic alopecia: a systematic review and meta-analysis
verfasst von: Patrick M Jedlowski
Michelle Anthony
Publikationsdatum: 01.12.2024
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2024
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-023-03946-4

Springer Medizin

Abstract

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