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Erschienen in: Infection 4/2022

25.02.2022 | Original Paper

Epidemiology of symptomatic infective anoproctitis in a population of men having sex with men (MSM)

verfasst von: J. Lourtet-Hascoet, L. Mine, L. Spindler, B. Pilmis, M. Aubert, A. EL Mituialy, V. Vieillefond, V. de Parades, A. Le Monnier

Erschienen in: Infection | Ausgabe 4/2022

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Abstract

Purpose

Anoproctitis due to Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are Sexual Transmitted Infections (STIs) reported in MSM population. This study describes clinical and microbiological epidemiology of infective anoproctitis in MSM population.

Methods

All patients with symptomatic anoproctitis consulting at the proctology Institute of Saint-Joseph’s Hospital, Paris, were included. Detection of CT/NG was performed by PCR GeneXpertR and other STIs pathogens Mycoplasma sp., HSV, CMV and T. pallidum were detected by multiplex PCR Allplex (mPCR).

Results

Symptoms most frequently reported were pain, rectal bleeding and purulent flow in 66%, 52% and 49% of cases, respectively. On the 311 rectal samples collected, 171 (55.2%) were positive to CT/NG. Among the 194 used for mPCR, 148 were positive to STIs pathogens (76.2%) including 106 samples (71.6%) positive in coinfections. Among NG infections, 22.6% of the strains were resistant to azithromycin and 26.8% to tetracyclines.

Conclusions

Anorectal infections in this MSM population showed a high prevalence of not only CT/NG but also other pathogens involved in STIs. The high level of coinfections confirms the requirement of accurate PCR tests to improve diagnosis. This study describing increasing antibiotic resistances for NG strains confirms the updating of international guidelines on antibiotic treatments recommendations.
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Metadaten
Titel
Epidemiology of symptomatic infective anoproctitis in a population of men having sex with men (MSM)
verfasst von
J. Lourtet-Hascoet
L. Mine
L. Spindler
B. Pilmis
M. Aubert
A. EL Mituialy
V. Vieillefond
V. de Parades
A. Le Monnier
Publikationsdatum
25.02.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Infection / Ausgabe 4/2022
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-022-01766-2

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