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Erschienen in:

15.03.2022 | Original Article

Impact of travel burden on clinical outcomes in lung cancer

verfasst von: Dragomir Svetozarov Stoyanov, Nikolay Vladimirov Conev, Ivan Shterev Donev, Ivan Dimitrov Tonev, Teodorika Vitalinova Panayotova, Eleonora Georgieva Dimitrova-Gospodinova

Erschienen in: Supportive Care in Cancer | Ausgabe 6/2022

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Abstract

Purpose

Our study explores the influence of travel burden (measured as travel distance and travel time) on clinical outcomes in lung cancer patients.

Methods

A retrospective analysis of a single Bulgarian center was performed. A total of 9240 lung cancer patients were included in the study. Travel distance and travel time between patients’ city of residence and the treating facility were calculated with an online tool to determine the shortest route for travel using the existing road network. The probability of survival was estimated using the Kaplan–Meier method, and differences in survival in each subgroup were evaluated with a log-rank test.

Results

About one third of all included patients were living in the same city as the treating facility (n = 2746, 29.7%). Overall survival in our patient population was significantly lower with increasing travel distance (p < 0.001, Mantel-Cox log rank) and travel time (p < 0.001, Mantel-Cox log rank). The 1-year OS rate according to travel distance was 27.1% in the same city group, 22.4% in < 50-km group, and 20.5% in ≥ 50-km group (p < 0.001). The corresponding values for the 5-year OS rate were 2.9%, 2.6%, and 1.4% (p < 0.001).

Conclusion

In this retrospective study, we discovered significant differences in the overall survival of patients with lung cancer depending on travel distance and travel time to the treating oncological facility. Despite having similar clinical and pathological characteristics (age, sex, stage at initial diagnosis, histologic subtype), the median overall survival was significantly lower in those subgroups of patients with a higher travel burden.

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Titel: Impact of travel burden on clinical outcomes in lung cancer
verfasst von: Dragomir Svetozarov Stoyanov
Nikolay Vladimirov Conev
Ivan Shterev Donev
Ivan Dimitrov Tonev
Teodorika Vitalinova Panayotova
Eleonora Georgieva Dimitrova-Gospodinova
Publikationsdatum: 15.03.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 6/2022
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-022-06978-8

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Impact of travel burden on clinical outcomes in lung cancer