Anticoagulant therapy is a mainstay in the management of patients with cardiovascular disease. The use of conventional anticoagulants carries potential side effects, mainly bleeding. Drugs targeting Factor XI (FXI) have been investigated in …
verfasst von:
Ahmed E. Ali, Mohamed K. Awad, Karim Ali, Mohamed Riad Abouzid, Marwan H. Ahmed, Muhammad S. Mazroua
Ischemic stroke patients with thrombophilia and patient foramen ovale (PFO) may have an increased risk of recurrent stroke and transient ischemic attack (TIA), and may benefit from PFO closure. However, screening for thrombophilia is not routinely …
verfasst von:
Xue Yang Lim, Nicholas LX Gao, Wynne Yu Lee, Jia Hui Neo, Alethea HE Tan, Ching-Hui Sia, Vijay K Sharma, Leonard LL Yeo, Yinghao Lim, Chee Yen Lin, Jamie Sin Ying Ho, Benjamin YQ Tan
Therapeutic anticoagulation showed inconsistent results in hospitalized patients with COVID-19 and selection of the best patients to use this strategy still a challenge balancing the risk of thrombotic and hemorrhagic outcomes. The present …
verfasst von:
Pedro Gabriel Melo de Barros e Silva, Remo H. M. Furtado, Mariana Silveira de Alcântara Chaud, Ariane Vieira Scarlatelli Macedo, Bruna Bronhara, Lucas Petri Damiani, Lilian Mazza Barbosa, Mayra Akimi Suiama, Eduardo Ramacciotti, Priscilla de Aquino Martins, Aryadne Lyrio de Oliveira, Vinicius Santana Nunes, Luiz Eduardo Fonteles Ritt, Ana Thereza Rocha, Lucas Tramujas, Sueli V. Santos, Dario Rafael Abregu Diaz, Lorena Souza Viana, Lívia Maria Garcia Melro, Estêvão Lanna Figueiredo, Fernando Carvalho Neuenschwander, Marianna Deway Andrade Dracoulakis, Rodolfo Godinho Souza Dourado Lima, Vicente Cés de Souza Dantas, Anne Cristine Silva Fernandes, Otávio Celso Eluf Gebara, Mauro Esteves Hernandes, Diego Aparecido Rios Queiroz, Viviane C. Veiga, Manoel Fernandes Canesin, Leonardo Meira de Faria, Gilson Soares Feitosa-Filho, Marcelo Basso Gazzana, Idelzuíta Leandro Liporace, Aline de Oliveira Twardowsky, Lilia Nigro Maia, Flávia Ribeiro Machado, Alexandre de Matos Soeiro, Germano Emílio Conceição-Souza, Luciana Armaganijan, Patrícia O. Guimarães, Regis G. Rosa, Luciano C. P. Azevedo, John H. Alexander, Alvaro Avezum, Otávio Berwanger, Alexandre B. Cavalcanti, Renato D. Lopes, on behalf of the ACTION Coalition COVID-19 Brazil IV Investigators
Hemodynamic assessment of patients with pulmonary embolism (PE) remains a fundamental component of early risk stratification that in turn, influences subsequent monitoring and therapeutic strategies. The current body of literature and …
verfasst von:
Marco Zuin, Stanislav Henkin, Eileen M. Harder, Gregory Piazza
An accurate diagnosis of venous thromboembolism (VTE) is crucial, given the potential for high mortality in undetected cases. Strategic D-dimer testing may aid in identifying low-risk patients, preventing overdiagnosis and reducing imaging costs.
verfasst von:
Teodora Biciusca, Leon D. Gruenewald, Simon S. Martin, Jennifer Gotta, Scherwin Mahmoudi, Katrin Eichler, Christian Booz, Christian Salbach, Matthias Müller-Hennessen, Moritz Biener, Mustafa Yildirim, Barbara Milles, Christof M. Sommer, Thomas J. Vogl, Evangelos Giannitsis, Vitali Koch
Statins were reported to have a potential effect of primary prevention of venous thromboembolism (VTE), although that of secondary prevention remains uncertain. To investigate the association between statins use and recurrent VTE in the current …
Venous thromboembolism, which is common in cancer patients and accompanies or even precedes malignant tumors, is known as cancer-related thrombosis and is an important cause of cancer- associated death. At present, the exact etiology of the …
verfasst von:
Yifan Zhang, Jingtong Zeng, Shihao Bao, Bo Zhang, Xianjie Li, Hanqing Wang, Yuan Cheng, Hao Zhang, Lingling Zu, Xiaohong Xu, Song Xu, Zuoqing Song
Cancer-associated thrombosis (CAT) is a serious complication and a leading cause of death second to cancer progression among patients with cancer [ 1 – 3 ]. Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism …
verfasst von:
Marie Linder, Anders Ekbom, Gunnar Brobert, Kai Vogtländer, Yanina Balabanova, Cecilia Becattini, Marc Carrier, Alexander T. Cohen, Craig I. Coleman, Alok A. Khorana, Agnes Y. Y. Lee, George Psaroudakis, Khaled Abdelgawwad, Marcela Rivera, Bernhard Schaefer, Diego Hernan Giunta
Anticoagulation therapy is standard for conditions like atrial fibrillation, venous thromboembolism, and valvular heart disease, yet it is unclear if there are ethnoracial disparities in its quality and delivery in the United States. For this …
verfasst von:
Sara R. Vazquez, Naomi Y. Yates, Craig J. Beavers, Darren M. Triller, Mary M. McFarland
COVID-19 has been associated with alterations in coagulation. Recent reports have shown that protein C and S activities are altered in COVID-19. This may affect the complications and outcome of the disease. However, their exact role in COVID-19 …
The efficacy and safety of dual antiplatelet therapy (DAPT) relative to intravenous (IV) alteplase in patients with acute minor ischemic stroke are insufficiently established. Therefore, we aimed to perform a meta-analysis to compare DAPT with IV …
verfasst von:
Patricia Viana, Jessica Hoffmann Relvas, Thamiris Dias Delfino Cabral, Jorge Eduardo Persson, Artur Menegaz de Almeida, Marina Persson, Marcos Vinícius Oliveira Marques, Jamary Oliveira-Filho
Intraoperative antithrombotic drug removal by haemoadsorption is a novel strategy to reduce perioperative bleeding in patients on antithrombotic drugs undergoing cardiac surgery. The international STAR registry reports real-world clinical outcomes …
verfasst von:
Michael Schmoeckel, Matthias Thielmann, Kambiz Hassan, Stephan Geidel, Jan Schmitto, Anna L. Meyer, Keti Vitanova, Andreas Liebold, Nandor Marczin, Martin H. Bernardi, Rene Tandler, Sandra Lindstedt, Marijana Matejic-Spasic, Daniel Wendt, Efthymios N. Deliargyris, Robert F. Storey
Acute promyelocytic leukemia (APL) stands out as a distinctive form of acute leukemia, exhibiting a higher occurrence of thrombotic events when contrasted with other leukemia subtypes. Since thrombosis is a relatively rare but unfavorable …
verfasst von:
Xiaojing Song, Cheng Chi, Weibo Gao, Wei Sun, Yang Liu, Xiaohui Zhang, Xiaojun Huang, Jihong Zhu, Yu Wang
Non-valvular atrial fibrillation (NVAF) is a cardiac arrhythmia and significant cause of stroke and mortality in the United States (US) [ 1 , 2 ]. Approximately 4% of NVAF patients experience stroke and around 11% die within 1 year of initial …
verfasst von:
Gregory Y. H. Lip, Virginia Noxon, Amiee Kang, Xuemei Luo, Nipun Atreja, Stella Han, Dong Cheng, Jenny Jiang, Lisa Abramovitz, Steven Deitelzweig
Cardiovascular thrombotic events have long been a perplexing factor in clinical settings, influencing patient prognoses significantly. Ultrasound-mediated acoustic therapy, an innovative thrombolytic treatment method known for its high efficiency …
verfasst von:
Zhiwen Wang, Nan Jiang, Zhixin Jiang, Qing Deng, Qing Zhou, Bo Hu
Patients diagnosed with lymphoma or multiple myeloma are at elevated risk of venous thromboembolism (VTE). Optimum risk stratification and effective thromboprophylaxis can only be achieved through the development of a multiple-specific risk score …
verfasst von:
Irene Sánchez Prieto, Isabel Gutiérrez Jomarrón, Celia Martínez Vázquez, Pedro Rodríguez Barquero, Paula Gili Herreros, Julio García-Suárez
Multimorbidity, i.e., two or more non-communicable diseases (NCDs), is an escalating challenge for society. Venous thromboembolism (VTE) is a common cardiovascular disease and it is unknown which multimorbidity clusters associates with VTE. Our …
verfasst von:
Jonatan Ahrén, MirNabi Pirouzifard, Björn Holmquist, Jan Sundquist, Kristina Sundquist, Bengt Zöller
Patients with COVID-19 develop an increased risk of thromboembolism. Thromboprophylaxis is recommended for hospitalized COVID-19 patients, but the role of thromboprophylaxis in outpatients with COVID-19 is less well defined. We conducted a …
