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12.04.2024 | Chronic Pain Medicine (O Viswanath, Section Editor)

Spinal Cord Stimulation Waveforms for the Treatment of Chronic Pain

verfasst von: Ahish Chitneni, Esha Jain, Sidharth Sahni, Philippe Mavrocordatos, Alaa Abd-Elsayed

Erschienen in: Current Pain and Headache Reports

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Abstract

Purpose of Review

Since the advent of spinal cord stimulation (SCS), advances in technology have allowed for improvement and treatment of various conditions, especially chronic pain. Additionally, as the system has developed, the ability to provide different stimulation waveforms for patients to treat different conditions has improved. The purpose and objective of the paper is to discuss basics of waveforms and present the most up-to-date literature and research studies on the different types of waveforms that currently exist. During our literature search, we came across over sixty articles that discuss the various waveforms we intend to evaluate.

Recent Findings

There are several publications on several waveforms used in clinical practice, but to our knowledge, this is the only educational document teaching on waveforms which provides essential knowledge.

Summary

There is a gap of knowledge related to understanding wave forms and how they work.
Literatur
1.
Zurück zum Zitat Rock AK, Truong H, Park YL, Pilitis J. Spinal cord stimulation. Neurosurg Clin N Am. 2019;30(2):169–94.CrossRefPubMed Rock AK, Truong H, Park YL, Pilitis J. Spinal cord stimulation. Neurosurg Clin N Am. 2019;30(2):169–94.CrossRefPubMed
4.
Zurück zum Zitat Miller JP, Eldabe S, Buchser E, Johanek LM, Guan Y, Linderoth B. Parameters of spinal cord stimulation and their role in electrical charge delivery: a review. Neuromodulation. 2016;19:373–84.CrossRefPubMed Miller JP, Eldabe S, Buchser E, Johanek LM, Guan Y, Linderoth B. Parameters of spinal cord stimulation and their role in electrical charge delivery: a review. Neuromodulation. 2016;19:373–84.CrossRefPubMed
7.
Zurück zum Zitat Head J, Mazza J, Sabourin V, Turpin J, Hoelscher C, Wu C, et al. Waves of pain relief: a systematic review of clinical trials in spinal cord stimulation waveforms for the treatment of chronic neuropathic low back and leg pain. World Neurosurg. 2019;131:264-74.e3.CrossRefPubMed Head J, Mazza J, Sabourin V, Turpin J, Hoelscher C, Wu C, et al. Waves of pain relief: a systematic review of clinical trials in spinal cord stimulation waveforms for the treatment of chronic neuropathic low back and leg pain. World Neurosurg. 2019;131:264-74.e3.CrossRefPubMed
9.
Zurück zum Zitat Russo M, Cousins MJ, Brooker C, Taylor N, Boesel T, Sullivan R, Poree L, Shariati NH, Hanson E, Parker J. Effective relief of pain and associated symptoms with closed-loop spinal cord stimulation system: preliminary results of the Avalon study. Neuromodulation. 2018;21(1):38–47. https://doi.org/10.1111/ner.12684. (Epub 2017 Sep 18 PMID: 28922517).CrossRefPubMed Russo M, Cousins MJ, Brooker C, Taylor N, Boesel T, Sullivan R, Poree L, Shariati NH, Hanson E, Parker J. Effective relief of pain and associated symptoms with closed-loop spinal cord stimulation system: preliminary results of the Avalon study. Neuromodulation. 2018;21(1):38–47. https://​doi.​org/​10.​1111/​ner.​12684. (Epub 2017 Sep 18 PMID: 28922517).CrossRefPubMed
10.
Zurück zum Zitat Vallejo R, Kelley CA, Gupta A, et al. Modulation of neuroglial interactions using differential target multiplexed spinal cord stimulation in an animal model of neuropathic pain. Mol Pain. 2020;16:1744806920918057.CrossRefPubMedPubMedCentral Vallejo R, Kelley CA, Gupta A, et al. Modulation of neuroglial interactions using differential target multiplexed spinal cord stimulation in an animal model of neuropathic pain. Mol Pain. 2020;16:1744806920918057.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat • Duarte RV, Nevitt S, Copley S, Maden M, de Vos CC, Taylor RS, Eldabe S. Systematic review and network meta-analysis of neurostimulation for painful diabetic neuropathy. Diabetes Care. 2022;45(10):2466–75. https://doi.org/10.2337/dc22-0932. Recent article discussing important disease condition.CrossRefPubMed • Duarte RV, Nevitt S, Copley S, Maden M, de Vos CC, Taylor RS, Eldabe S. Systematic review and network meta-analysis of neurostimulation for painful diabetic neuropathy. Diabetes Care. 2022;45(10):2466–75. https://​doi.​org/​10.​2337/​dc22-0932Recent article discussing important disease condition.CrossRefPubMed
12.
Zurück zum Zitat •• Ho E, Yazdanpanah N, Ho J, Drukman B, Chang A, Agarwal S. Parameters of spinal cord stimulation in complex regional pain syndrome: systematic review and meta-analysis of randomized controlled trials. Pain Physician. 2022;25(8):521–30. Recent article with analysks of clinical trials.PubMed •• Ho E, Yazdanpanah N, Ho J, Drukman B, Chang A, Agarwal S. Parameters of spinal cord stimulation in complex regional pain syndrome: systematic review and meta-analysis of randomized controlled trials. Pain Physician. 2022;25(8):521–30. Recent article with analysks of clinical trials.PubMed
14.
Zurück zum Zitat Van Beek M, Geurts JW, Slangen R, Schaper NC, Faber CG, Joosten EA, Dirksen CD, van Dongen RT, van Kuijk SMJ, van Kleef M. Severity of neuropathy is associated with long-term spinal cord stimulation outcome in painful diabetic peripheral neuropathy: five-year follow-up of a prospective two-center clinical trial. Diabetes Care. 2018;41(1):32–8. https://doi.org/10.2337/dc17-0983.CrossRefPubMed Van Beek M, Geurts JW, Slangen R, Schaper NC, Faber CG, Joosten EA, Dirksen CD, van Dongen RT, van Kuijk SMJ, van Kleef M. Severity of neuropathy is associated with long-term spinal cord stimulation outcome in painful diabetic peripheral neuropathy: five-year follow-up of a prospective two-center clinical trial. Diabetes Care. 2018;41(1):32–8. https://​doi.​org/​10.​2337/​dc17-0983.CrossRefPubMed
16.
Zurück zum Zitat Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB. The effects of spinal cord stimulation in neuropathic pain are sustained: a 24-month follow-up of the prospective randomized controlled multicenter trial of the effectiveness of spinal cord stimulation. Neurosurgery. 2008;63(4):762–70. https://doi.org/10.1227/01.NEU.0000325731.46702.D9.CrossRefPubMed Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB. The effects of spinal cord stimulation in neuropathic pain are sustained: a 24-month follow-up of the prospective randomized controlled multicenter trial of the effectiveness of spinal cord stimulation. Neurosurgery. 2008;63(4):762–70. https://​doi.​org/​10.​1227/​01.​NEU.​0000325731.​46702.​D9.CrossRefPubMed
18.
Zurück zum Zitat De Andres J, Monsalve-Dolz V, Fabregat-Cid G, Villanueva-Perez V, Harutyunyan A, Asensio-Samper JM, Sanchis-Lopez N. Prospective, randomized blind effect-on-outcome study of conventional vs high-frequency spinal cord stimulation in patients with pain and disability due to failed back surgery syndrome. Pain medicine (Malden, Mass). 2017;18(12):2401–21. https://doi.org/10.1093/pm/pnx241.CrossRefPubMed De Andres J, Monsalve-Dolz V, Fabregat-Cid G, Villanueva-Perez V, Harutyunyan A, Asensio-Samper JM, Sanchis-Lopez N. Prospective, randomized blind effect-on-outcome study of conventional vs high-frequency spinal cord stimulation in patients with pain and disability due to failed back surgery syndrome. Pain medicine (Malden, Mass). 2017;18(12):2401–21. https://​doi.​org/​10.​1093/​pm/​pnx241.CrossRefPubMed
19.
Zurück zum Zitat Eldabe S, Duarte R, Gulve A, Williams H, Garner F, Brookes M, Madzinga G, Buchser E, Batterham AM. Analgesic efficacy of “burst” and tonic (500 Hz) spinal cord stimulation patterns: a randomized placebo-controlled crossover study. Neuromodulation : journal of the International Neuromodulation Society. 2021;24(3):471–8. https://doi.org/10.1111/ner.13321.CrossRefPubMed Eldabe S, Duarte R, Gulve A, Williams H, Garner F, Brookes M, Madzinga G, Buchser E, Batterham AM. Analgesic efficacy of “burst” and tonic (500 Hz) spinal cord stimulation patterns: a randomized placebo-controlled crossover study. Neuromodulation : journal of the International Neuromodulation Society. 2021;24(3):471–8. https://​doi.​org/​10.​1111/​ner.​13321.CrossRefPubMed
21.
Zurück zum Zitat Chakravarthy K, Richter H, Christo PJ, Williams K, Guan Y. Spinal cord stimulation for treating chronic pain: reviewing preclinical and clinical data on paresthesia-free high-frequency therapy. Neuromodulation. 2018;21(1):10–8. https://doi.org/10.1111/ner.12721. Epub 2017 Nov 3. PMID: 29105244; PMCID: PMC5766402.CrossRefPubMed Chakravarthy K, Richter H, Christo PJ, Williams K, Guan Y. Spinal cord stimulation for treating chronic pain: reviewing preclinical and clinical data on paresthesia-free high-frequency therapy. Neuromodulation. 2018;21(1):10–8. https://​doi.​org/​10.​1111/​ner.​12721. Epub 2017 Nov 3. PMID: 29105244; PMCID: PMC5766402.CrossRefPubMed
22.
Zurück zum Zitat •• Hoelzer BC, Edgar D, Lu SP, Taylor RS. Indirect comparison of 10 kHz spinal cord stimulation (SCS) versus traditional low-frequency scs for the treatment of painful diabetic neuropathy: a systematic review of randomized controlled trials. Biomedicines. 2022;10(10):2630. https://doi.org/10.3390/biomedicines10102630. PMID: 36289892; PMCID: PMC9599433. Article discussing one of the earliest modern waveforms.CrossRefPubMedPubMedCentral •• Hoelzer BC, Edgar D, Lu SP, Taylor RS. Indirect comparison of 10 kHz spinal cord stimulation (SCS) versus traditional low-frequency scs for the treatment of painful diabetic neuropathy: a systematic review of randomized controlled trials. Biomedicines. 2022;10(10):2630. https://​doi.​org/​10.​3390/​biomedicines1010​2630. PMID: 36289892; PMCID: PMC9599433. Article discussing one of the earliest modern waveforms.CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Petersen EA, Stauss TG, Scowcroft JA, Brooks ES, White JL, Sills SM, Amirdelfan K, Guirguis MN, Xu J, Yu C, Nairizi A, Patterson DG, Tsoulfas KC, Creamer MJ, Galan V, Bundschu RH, Paul CA, Mehta ND, Choi H, Sayed D, Mekhail NA. Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy: a randomized clinical trial. JAMA neurology. 2021;78(6):687–98. https://doi.org/10.1001/jamaneurol.2021.0538.CrossRefPubMedPubMedCentral Petersen EA, Stauss TG, Scowcroft JA, Brooks ES, White JL, Sills SM, Amirdelfan K, Guirguis MN, Xu J, Yu C, Nairizi A, Patterson DG, Tsoulfas KC, Creamer MJ, Galan V, Bundschu RH, Paul CA, Mehta ND, Choi H, Sayed D, Mekhail NA. Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy: a randomized clinical trial. JAMA neurology. 2021;78(6):687–98. https://​doi.​org/​10.​1001/​jamaneurol.​2021.​0538.CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Hagedorn JM, Romero J, Thuc Ha C, Bendel MA, D’Souza RS. Paresthesia-based versus high-frequency spinal cord stimulation: a retrospective, real-world, single-center comparison. Neuromodulation : journal of the International Neuromodulation Society. 2021. Advance online publication. https://doi.org/10.1111/ner.13497. Hagedorn JM, Romero J, Thuc Ha C, Bendel MA, D’Souza RS. Paresthesia-based versus high-frequency spinal cord stimulation: a retrospective, real-world, single-center comparison. Neuromodulation : journal of the International Neuromodulation Society. 2021. Advance online publication. https://​doi.​org/​10.​1111/​ner.​13497.
27.
29.
Zurück zum Zitat Perruchoud C, Eldabe S, Batterham AM, Madzinga G, Brookes M, Durrer A, Rosato M, Bovet N, West S, Bovy M, Rutschmann B, Gulve A, Garner F, Buchser E. Analgesic efficacy of high-frequency spinal cord stimulation: a randomized double-blind placebo-controlled study. Neuromodulation : journal of the International Neuromodulation Society. 2013;16(4):363–9. https://doi.org/10.1111/ner.12027.CrossRefPubMed Perruchoud C, Eldabe S, Batterham AM, Madzinga G, Brookes M, Durrer A, Rosato M, Bovet N, West S, Bovy M, Rutschmann B, Gulve A, Garner F, Buchser E. Analgesic efficacy of high-frequency spinal cord stimulation: a randomized double-blind placebo-controlled study. Neuromodulation : journal of the International Neuromodulation Society. 2013;16(4):363–9. https://​doi.​org/​10.​1111/​ner.​12027.CrossRefPubMed
31.
Zurück zum Zitat Kapural L, Yu C, Doust MW, Gliner BE, Vallejo R, Sitzman BT, Amirdelfan K, Morgan DM, Brown LL, Yearwood TL, Bundschu R, Burton AW, Yang T, Benyamin R, Burgher AH. Novel 10-kHz high-frequency therapy (HF10 therapy) is superior to traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: the SENZA-RCT randomized controlled trial. Anesthesiology. 2015;123(4):851–60. https://doi.org/10.1097/ALN.0000000000000774.CrossRefPubMed Kapural L, Yu C, Doust MW, Gliner BE, Vallejo R, Sitzman BT, Amirdelfan K, Morgan DM, Brown LL, Yearwood TL, Bundschu R, Burton AW, Yang T, Benyamin R, Burgher AH. Novel 10-kHz high-frequency therapy (HF10 therapy) is superior to traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: the SENZA-RCT randomized controlled trial. Anesthesiology. 2015;123(4):851–60. https://​doi.​org/​10.​1097/​ALN.​0000000000000774​.CrossRefPubMed
32.
Zurück zum Zitat Al-Kaisy A, Van Buyten JP, Smet I, Palmisani S, Pang D, Smith T. Sustained effectiveness of 10 kHz high-frequency spinal cord stimulation for patients with chronic, low back pain: 24-month results of a prospective multicenter study. Pain medicine (Malden, Mass). 2014;15(3):347–54. https://doi.org/10.1111/pme.12294.CrossRefPubMed Al-Kaisy A, Van Buyten JP, Smet I, Palmisani S, Pang D, Smith T. Sustained effectiveness of 10 kHz high-frequency spinal cord stimulation for patients with chronic, low back pain: 24-month results of a prospective multicenter study. Pain medicine (Malden, Mass). 2014;15(3):347–54. https://​doi.​org/​10.​1111/​pme.​12294.CrossRefPubMed
33.
Zurück zum Zitat Van Buyten JP, Al-Kaisy A, Smet I, Palmisani S, Smith T. High-frequency spinal cord stimulation for the treatment of chronic back pain patients: results of a prospective multicenter European clinical study. Neuromodulation : journal of the International Neuromodulation Society. 2013;16(1):59–66. https://doi.org/10.1111/ner.12006.CrossRefPubMed Van Buyten JP, Al-Kaisy A, Smet I, Palmisani S, Smith T. High-frequency spinal cord stimulation for the treatment of chronic back pain patients: results of a prospective multicenter European clinical study. Neuromodulation : journal of the International Neuromodulation Society. 2013;16(1):59–66. https://​doi.​org/​10.​1111/​ner.​12006.CrossRefPubMed
34.
Zurück zum Zitat Conger A, Sperry BP, Cheney CW, Burnham TM, Mahan MA, Onofrei LV, Cushman DM, Wagner GE, Shipman H, Teramoto M, McCormick ZL. The effectiveness of spinal cord stimulation for the treatment of axial low back pain: a systematic review with narrative synthesis. Pain Med. 2020;21(11):2699–712. https://doi.org/10.1093/pm/pnaa142. (PMID: 32472130).CrossRefPubMed Conger A, Sperry BP, Cheney CW, Burnham TM, Mahan MA, Onofrei LV, Cushman DM, Wagner GE, Shipman H, Teramoto M, McCormick ZL. The effectiveness of spinal cord stimulation for the treatment of axial low back pain: a systematic review with narrative synthesis. Pain Med. 2020;21(11):2699–712. https://​doi.​org/​10.​1093/​pm/​pnaa142. (PMID: 32472130).CrossRefPubMed
39.
Zurück zum Zitat Deer T, Slavin KV, Amirdelfan K, North RB, Burton AW, Yearwood TL, Tavel E, Staats P, Falowski S, Pope J, Justiz R, Fabi AY, Taghva A, Paicius R, Houden T, Wilson D. Success using neuromodulation with BURST (SUNBURST) study: results from a prospective, randomized controlled trial using a novel burst waveform. Neuromodulation. 2018;21(1):56–66. https://doi.org/10.1111/ner.12698. (Epub 2017 Sep 29 PMID: 28961366).CrossRefPubMed Deer T, Slavin KV, Amirdelfan K, North RB, Burton AW, Yearwood TL, Tavel E, Staats P, Falowski S, Pope J, Justiz R, Fabi AY, Taghva A, Paicius R, Houden T, Wilson D. Success using neuromodulation with BURST (SUNBURST) study: results from a prospective, randomized controlled trial using a novel burst waveform. Neuromodulation. 2018;21(1):56–66. https://​doi.​org/​10.​1111/​ner.​12698. (Epub 2017 Sep 29 PMID: 28961366).CrossRefPubMed
42.
Zurück zum Zitat Mekhail N, Levy RM, Deer TR, Kapural L, Li S, Amirdelfan K, Hunter CW, Rosen SM, Costandi SJ, Falowski SM, Burgher AH, Pope JE, Gilmore CA, Qureshi FA, Staats PS, Scowcroft J, Carlson J, Kim CK, Yang MI, Stauss T, Poree L. Evoke Study Group. Long-term safety and efficacy of closed-loop spinal cord stimulation to treat chronic back and leg pain (Evoke): a double-blind, randomized, controlled trial. Lancet Neurol. 2020;(2):123–134. https://doi.org/10.1016/S1474-4422(19)30414-4. Epub 2019 Dec 20. PMID: 31870766. Mekhail N, Levy RM, Deer TR, Kapural L, Li S, Amirdelfan K, Hunter CW, Rosen SM, Costandi SJ, Falowski SM, Burgher AH, Pope JE, Gilmore CA, Qureshi FA, Staats PS, Scowcroft J, Carlson J, Kim CK, Yang MI, Stauss T, Poree L. Evoke Study Group. Long-term safety and efficacy of closed-loop spinal cord stimulation to treat chronic back and leg pain (Evoke): a double-blind, randomized, controlled trial. Lancet Neurol. 2020;(2):123–134. https://​doi.​org/​10.​1016/​S1474-4422(19)30414-4. Epub 2019 Dec 20. PMID: 31870766.
43.
Zurück zum Zitat Mekhail N, Levy RM, Deer TR, Kapural L, Li S, Amirdelfan K, Hunter CW, Rosen SM, Costandi SJ, Falowski SM, Burgher AH, Pope JE, Gilmore CA, Qureshi FA, Staats PS, Scowcroft J, McJunkin T, Carlson J, Kim CK, Yang MI, Stauss T, Pilitsis J, Poree L, Evoke Study Group, Brounstein D, Gilbert S, Gmel GE, Gorman R, Gould I, Hanson E, Karantonis DM, Khurram A, Leitner A, Mugan D, Obradovic M, Ouyang Z, Parker J, Single P, Soliday N. Durability of clinical and quality-of-life outcomes of closed-loop spinal cord stimulation for chronic back and leg pain: a secondary analysis of the evoke randomized clinical trial. JAMA Neurol. 2022;79(3):251–60. https://doi.org/10.1001/jamaneurol.2021.4998. Erratum in: JAMA Neurol. 2022 Feb 14;:null. PMID: 34998276; PMCID: PMC8742908.CrossRefPubMedPubMedCentral Mekhail N, Levy RM, Deer TR, Kapural L, Li S, Amirdelfan K, Hunter CW, Rosen SM, Costandi SJ, Falowski SM, Burgher AH, Pope JE, Gilmore CA, Qureshi FA, Staats PS, Scowcroft J, McJunkin T, Carlson J, Kim CK, Yang MI, Stauss T, Pilitsis J, Poree L, Evoke Study Group, Brounstein D, Gilbert S, Gmel GE, Gorman R, Gould I, Hanson E, Karantonis DM, Khurram A, Leitner A, Mugan D, Obradovic M, Ouyang Z, Parker J, Single P, Soliday N. Durability of clinical and quality-of-life outcomes of closed-loop spinal cord stimulation for chronic back and leg pain: a secondary analysis of the evoke randomized clinical trial. JAMA Neurol. 2022;79(3):251–60. https://​doi.​org/​10.​1001/​jamaneurol.​2021.​4998. Erratum in: JAMA Neurol. 2022 Feb 14;:null. PMID: 34998276; PMCID: PMC8742908.CrossRefPubMedPubMedCentral
44.
Zurück zum Zitat Brooker C, Russo M, Cousins MJ, Taylor N, Holford L, Martin R, Boesel T, Sullivan R, Hanson E, Gmel GE, Shariati NH, Poree L, Parker J. ECAP-controlled closed-loop spinal cord stimulation efficacy and opioid reduction over 24-months: final results of the prospective, multicenter, open-label Avalon study. Pain Pract. 2021;(6):680–691. https://doi.org/10.1111/papr.13008. Epub 2021 May 2. PMID: 33768664; PMCID: PMC8359972. Brooker C, Russo M, Cousins MJ, Taylor N, Holford L, Martin R, Boesel T, Sullivan R, Hanson E, Gmel GE, Shariati NH, Poree L, Parker J. ECAP-controlled closed-loop spinal cord stimulation efficacy and opioid reduction over 24-months: final results of the prospective, multicenter, open-label Avalon study. Pain Pract. 2021;(6):680–691. https://​doi.​org/​10.​1111/​papr.​13008. Epub 2021 May 2. PMID: 33768664; PMCID: PMC8359972.
47.
Zurück zum Zitat Fishman MA, Calodney A, Kim P, Slezak J, Benyamin R, Rehman A, et al. Prospective, multicenter feasibility study to evaluate differential target multiplexed spinal cord stimulation programming in subjects with chronic intractable back pain with or without leg pain. Pain Pract. 2020;20(7):761–8.CrossRefPubMed Fishman MA, Calodney A, Kim P, Slezak J, Benyamin R, Rehman A, et al. Prospective, multicenter feasibility study to evaluate differential target multiplexed spinal cord stimulation programming in subjects with chronic intractable back pain with or without leg pain. Pain Pract. 2020;20(7):761–8.CrossRefPubMed
48.
Zurück zum Zitat Fishman M, Cordner H, Justiz R, Provenzano D, Merrell C, Shah B, Naranjo J, Kim P, Calodney A, Carlson J, Bundschu R, Sanapati M, Mangal V, Vallejo R. Twelve-Month results from multicenter, open-label, randomized controlled clinical trial comparing differential target multiplexed spinal cord stimulation and traditional spinal cord stimulation in subjects with chronic intractable back pain and leg pain. Pain Pract. 2021;21(8):912–23. https://doi.org/10.1111/papr.13066. Epub 2021 Aug 27. PMID: 34363307; PMCID: PMC9290817.CrossRefPubMedPubMedCentral Fishman M, Cordner H, Justiz R, Provenzano D, Merrell C, Shah B, Naranjo J, Kim P, Calodney A, Carlson J, Bundschu R, Sanapati M, Mangal V, Vallejo R. Twelve-Month results from multicenter, open-label, randomized controlled clinical trial comparing differential target multiplexed spinal cord stimulation and traditional spinal cord stimulation in subjects with chronic intractable back pain and leg pain. Pain Pract. 2021;21(8):912–23. https://​doi.​org/​10.​1111/​papr.​13066. Epub 2021 Aug 27. PMID: 34363307; PMCID: PMC9290817.CrossRefPubMedPubMedCentral
49.
Zurück zum Zitat Fukaya N, Tanei T, Nishimura Y, Hara M, Hata N, Nagashima Y, Maesawa S, Araki Y, Saito R. Spinal cord stimulation for neuropathic pain following a spinal cord lesion with past spinal surgical histories using a paddle lead placed on the rostral side of the lesion: report of three cases. NMC Case Rep J. 2022;13(9):349–55. https://doi.org/10.2176/jns-nmc.2022-0218. PMID:36381134;PMCID:PMC9633090 .CrossRef Fukaya N, Tanei T, Nishimura Y, Hara M, Hata N, Nagashima Y, Maesawa S, Araki Y, Saito R. Spinal cord stimulation for neuropathic pain following a spinal cord lesion with past spinal surgical histories using a paddle lead placed on the rostral side of the lesion: report of three cases. NMC Case Rep J. 2022;13(9):349–55. https://​doi.​org/​10.​2176/​jns-nmc.​2022-0218. PMID:36381134;PMCID:PMC9633090 .CrossRef
51.
Zurück zum Zitat De Jaeger M, Goudman L, Brouns R, De Smedt A, Linderoth B, Eldabe S, Discover consortium, Moens M. The long-term response to high-dose spinal cord stimulation in patients with failed back surgery syndrome after conversion from standard spinal cord stimulation: an effectiveness and prediction study. Neuromodulation. 2021;24(3):546–55. https://doi.org/10.1111/ner.13138. Epub 2020 Mar 12. PMID: 32166849.CrossRefPubMed De Jaeger M, Goudman L, Brouns R, De Smedt A, Linderoth B, Eldabe S, Discover consortium, Moens M. The long-term response to high-dose spinal cord stimulation in patients with failed back surgery syndrome after conversion from standard spinal cord stimulation: an effectiveness and prediction study. Neuromodulation. 2021;24(3):546–55. https://​doi.​org/​10.​1111/​ner.​13138. Epub 2020 Mar 12. PMID: 32166849.CrossRefPubMed
53.
54.
57.
Zurück zum Zitat Desai MJ, Salmon J, Verrills P, Mitchell B, Du Toit N, Bates D, Vajramani G, Williams A, Love-Jones S, Patel N, Nikolic S, Mehta V, Ahmad A, Yu J, Christellis N, Harkin S, Baranidharan G, Levy R, Staats P, Malinowski MN, Makous J, Sullivan N, Kottalgi S, Hartley M, Mishra LN. A novel pulsed stimulation pattern in spinal cord stimulation: clinical results and postulated mechanisms of action in the treatment of chronic low back and leg pain. Neuromodulation. 2023;26(1):182–91. https://doi.org/10.1016/j.neurom.2022.10.053. (Epub 2022 Dec 9 PMID: 36503999).CrossRefPubMed Desai MJ, Salmon J, Verrills P, Mitchell B, Du Toit N, Bates D, Vajramani G, Williams A, Love-Jones S, Patel N, Nikolic S, Mehta V, Ahmad A, Yu J, Christellis N, Harkin S, Baranidharan G, Levy R, Staats P, Malinowski MN, Makous J, Sullivan N, Kottalgi S, Hartley M, Mishra LN. A novel pulsed stimulation pattern in spinal cord stimulation: clinical results and postulated mechanisms of action in the treatment of chronic low back and leg pain. Neuromodulation. 2023;26(1):182–91. https://​doi.​org/​10.​1016/​j.​neurom.​2022.​10.​053. (Epub 2022 Dec 9 PMID: 36503999).CrossRefPubMed
63.
Zurück zum Zitat Kinfe TM, Muhammad S, Link C, Roeske S, Chaudhry SR, Yearwood TL. Burst spinal cord stimulation increases peripheral antineuroinflammatory interleukin 10 levels in failed back surgery syndrome patients with predominant back pain. Neuromodulation. 2017;20(4):322–30. https://doi.org/10.1111/ner.12586. (Epub 2017 Feb 13 PMID: 28194840).CrossRefPubMed Kinfe TM, Muhammad S, Link C, Roeske S, Chaudhry SR, Yearwood TL. Burst spinal cord stimulation increases peripheral antineuroinflammatory interleukin 10 levels in failed back surgery syndrome patients with predominant back pain. Neuromodulation. 2017;20(4):322–30. https://​doi.​org/​10.​1111/​ner.​12586. (Epub 2017 Feb 13 PMID: 28194840).CrossRefPubMed
64.
Zurück zum Zitat Chen JL, Hesseltine AW, Nashi SE, Sills SM, McJunkin TL, Patil S, Bharara M, Caraway DL, Brooks ES. A real-world analysis of high-frequency 10 kHz spinal cord stimulation for the treatment of painful diabetic peripheral neuropathy. J Diabetes Sci Technol. 2022;16(2):282–8. https://doi.org/10.1177/19322968211060316. Epub 2021 Nov 29. PMID: 34842489; PMCID: PMC8861794.CrossRefPubMed Chen JL, Hesseltine AW, Nashi SE, Sills SM, McJunkin TL, Patil S, Bharara M, Caraway DL, Brooks ES. A real-world analysis of high-frequency 10 kHz spinal cord stimulation for the treatment of painful diabetic peripheral neuropathy. J Diabetes Sci Technol. 2022;16(2):282–8. https://​doi.​org/​10.​1177/​1932296821106031​6. Epub 2021 Nov 29. PMID: 34842489; PMCID: PMC8861794.CrossRefPubMed
69.
Zurück zum Zitat Berger AA, Urits I, Hasoon J, Gill J, Aner M, Yazdi CA, Viswanath O, Cornett EM, Kaye AD, Imani F, Imani F, Varrassi G, Simopoulos TT. Improved pain control with combination spinal cord stimulator therapy utilizing sub-perception and traditional paresthesia based waveforms: a pilot study. Anesth Pain Med. 2021;11(1):e113089. https://doi.org/10.5812/aapm.113089 PMID:34221951;PMCID:PMC8241823.CrossRefPubMedPubMedCentral Berger AA, Urits I, Hasoon J, Gill J, Aner M, Yazdi CA, Viswanath O, Cornett EM, Kaye AD, Imani F, Imani F, Varrassi G, Simopoulos TT. Improved pain control with combination spinal cord stimulator therapy utilizing sub-perception and traditional paresthesia based waveforms: a pilot study. Anesth Pain Med. 2021;11(1):e113089. https://​doi.​org/​10.​5812/​aapm.​113089 PMID:34221951;PMCID:PMC8241823.CrossRefPubMedPubMedCentral
Metadaten
Titel
Spinal Cord Stimulation Waveforms for the Treatment of Chronic Pain
verfasst von
Ahish Chitneni
Esha Jain
Sidharth Sahni
Philippe Mavrocordatos
Alaa Abd-Elsayed
Publikationsdatum
12.04.2024
Verlag
Springer US
Erschienen in
Current Pain and Headache Reports
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-024-01247-1

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