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Erschienen in:
28.05.2023 | Original Article
The effect of four weeks blood flow restricted resistance training on macro- and micro-vascular function in healthy, young men
Erschienen in: European Journal of Applied Physiology | Ausgabe 10/2023
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Purpose
To determine the macrovascular and microvascular function responses to resistance training with blood flow restriction (BFR) compared to high-load resistance training (HLRT) control group.
Methods
Twenty-four young, healthy men were randomly assigned to BFR or HLRT. Participants performed bilateral knee extensions and leg presses 4 days per week, for 4 weeks. For each exercise, BFR completed 3 X 10 repetitions/day at 30% of 1-repetition max (RM). The occlusive pressure was applied at 1.3 times of individual systolic blood pressure. The exercise prescription was identical for HLRT, except the intensity was set at 75% of one repetition maximum. Outcomes were measured pre-, at 2- and 4-weeks during the training period. The primary macrovascular function outcome was heart-ankle pulse wave velocity (haPWV), and the primary microvascular function outcome was tissue oxygen saturation (StO2) area under the curve (AUC) response to reactive hyperemia.
Results
Knee extension and leg press 1-RM increased by 14% for both groups. There was a significant interaction effect for haPWV, decreasing − 5% (Δ−0.32 m/s, 95% confidential interval [CI] − 0.51 to – 0.12, effect size [ES] = − 0.53) for BFR and increasing 1% (Δ0.03 m/s, 95%CI − 0.17 to 0.23, ES = 0.05) for HLRT. Similarly, there was an interaction effect for StO2 AUC, increasing 5% (Δ47%･s, 95%CI − 3.07 to 98.1, ES = 0.28) for HLRT and 17% (Δ159%･s, 95%CI 108.23–209.37, ES = 0.93) for BFR group.
Conclusion
The current findings suggest that BFR may improve macro- and microvascular function compared to HLRT.