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Current Geriatrics Reports

Erschienen in:

18.11.2020 | Nutrition, Obesity, and Diabetes (SML Ribeiro, Section Editor)

Type 2 Diabetes and Mediterranean Diet in Older Adults: a Brief Review of the Evidence

verfasst von: Eirini Mamalaki, Vassilis Balomenos, Nikolaos Scarmeas, Mary Yannakoulia

Erschienen in: Current Geriatrics Reports | Ausgabe 4/2020

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Abstract

Purpose of Review

Mediterranean diet is a traditional, plant-based dietary pattern extensively studied for its favorable health effects. In relation to type 2 diabetes (T2D), higher adherence to the Mediterranean dietary pattern is associated with a lower risk for incidence of diabetes, better glycemic control, and improvements in cardiovascular risk factors in diabetic patients.

Recent Findings

Interestingly, most of the studies on the relationship between T2D and adherence to the Mediterranean diet have focused on younger people, whereas the available evidence in older adults (≥ 60 years old) is limited. In this age group, the quality of the diet may be affected by factors that are associated with aging, including cognitive decline, whereas T2D has been associated with an elevated risk of cognitive deficits. More studies are needed in this age group in order to further investigate the potentially crucial role of T2D and glycemic control on cognition and their relationship with Mediterranean diet and to define the underlying mechanisms.

Summary

In any case, healthcare professionals should educate older adults in adopting the basic principles of the Mediterranean diet or of other plant-based dietary patterns, as a diet promoting cognitive and cardiovascular health.

Keys A, Menotti A, Karvonen MJ, Aravanis C, Blackburn H, Buzina R, et al. The diet and 15-year death rate in the seven countries study. Am J Epidemiol. 1986;124(6):903–15.CrossRefPubMed

Willett WC, Sacks F, Trichopoulou A, Drescher G, Ferro-Luzzi A, Helsing E, et al. Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr. 1995;61(6 Suppl):1402S–6S. https://doi.org/10.1093/ajcn/61.6.1402S.CrossRefPubMed

Eleftheriou D, Benetou V, Trichopoulou A, La Vecchia C, Bamia C. Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. Br J Nutr. 2018;120(10):1081–97. https://doi.org/10.1017/S0007114518002593.CrossRefPubMed

Sofi F, Macchi C, Abbate R, Gensini GF, Casini A. Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score. Public Health Nutr. 2014;17(12):2769–82. https://doi.org/10.1017/S1368980013003169.CrossRefPubMed

Yannakoulia M, Kontogianni M, Scarmeas N. Cognitive health and Mediterranean diet: just diet or lifestyle pattern? Ageing Res Rev. 2015;20:74–8. https://doi.org/10.1016/j.arr.2014.10.003.CrossRefPubMed

Anastasiou CA, Yannakoulia M, Kontogianni MD, Kosmidis MH, Mamalaki E, Dardiotis E, et al. Mediterranean lifestyle in relation to cognitive health: results from the HELIAD Study. Nutrients. 2018;10(10). https://doi.org/10.3390/nu10101557.

Esposito K, Maiorino MI, Bellastella G, Panagiotakos DB, Giugliano D. Mediterranean diet for type 2 diabetes: cardiometabolic benefits. Endocrine. 2017;56(1):27–32. https://doi.org/10.1007/s12020-016-1018-2.CrossRefPubMed

Koloverou E, Esposito K, Giugliano D, Panagiotakos D. The effect of Mediterranean diet on the development of type 2 diabetes mellitus: a meta-analysis of 10 prospective studies and 136,846 participants. Metab Clin Exp. 2014;63(7):903–11. https://doi.org/10.1016/j.metabol.2014.04.010.CrossRefPubMed

Esposito K, Maiorino MI, Bellastella G, Chiodini P, Panagiotakos D, Giugliano D. A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses. BMJ Open. 2015;5(8):e008222. https://doi.org/10.1136/bmjopen-2015-008222.CrossRefPubMedPubMedCentral

10.

Yannakoulia M, Mamalaki E, Anastasiou CA, Mourtzi N, Lambrinoudaki I, Scarmeas N. Eating habits and behaviors of older people: where are we now and where should we go? Maturitas. 2018;114:14–21. https://doi.org/10.1016/j.maturitas.2018.05.001.CrossRefPubMed

11.

Amarya S, Singh K, Sabharwal M. Changes during aging and their association with malnutrition. J Clin Gerontol Geriatr. 2015;6(3):78–84. https://doi.org/10.1016/j.jcgg.2015.05.003.CrossRef

12.

Harada CN, Natelson Love MC, Triebel KL. Normal cognitive aging. Clin Geriatr Med. 2013;29(4):737–52. https://doi.org/10.1016/j.cger.2013.07.002.CrossRefPubMedPubMedCentral

13.

Christiansen L, Sanmartin Berglund J, Lindberg C, Anderberg P, Skär L. Health-related quality of life and related factors among a sample of older people with cognitive impairment. Nurs Open. 2019;6(3):849–59. https://doi.org/10.1002/nop2.265.CrossRefPubMedPubMedCentral

14.

Reppermund S, Brodaty H, Crawford JD, Kochan NA, Draper B, Slavin MJ, et al. Impairment in instrumental activities of daily living with high cognitive demand is an early marker of mild cognitive impairment: the Sydney memory and ageing study. Psychol Med. 2013;43(11):2437–45. https://doi.org/10.1017/S003329171200308X.CrossRefPubMed

15.

Gonzalez-Colaco Harmand M, Meillon C, Rullier L, Avila-Funes JA, Bergua V, Dartigues JF, et al. Cognitive decline after entering a nursing home: a 22-year follow-up study of institutionalized and noninstitutionalized elderly people. J Am Med Dir Assoc. 2014;15(7):504–8. https://doi.org/10.1016/j.jamda.2014.02.006.CrossRefPubMed

16.

Agarwal KS, Kazim R, Xu J, Borson S, Taffet GE. Unrecognized cognitive impairment and its effect on heart failure readmissions of elderly adults. J Am Geriatr Soc. 2016;64(11):2296–301. https://doi.org/10.1111/jgs.14471.CrossRefPubMed

17.

Salas-Salvado J, Bullo M, Estruch R, Ros E, Covas MI, Ibarrola-Jurado N, et al. Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial. Ann Intern Med. 2014;160(1):1–10. https://doi.org/10.7326/M13-1725.CrossRefPubMed

18.

Diez-Espino J, Buil-Cosiales P, Serrano-Martinez M, Toledo E, Salas-Salvado J, Martinez-Gonzalez MA. Adherence to the Mediterranean diet in patients with type 2 diabetes mellitus and HbA1c level. Ann Nutr Metab. 2011;58(1):74–8. https://doi.org/10.1159/000324718.CrossRefPubMed

19.

Alonso-Dominguez R, Gomez-Marcos MA, Patino-Alonso MC, Sanchez-Aguadero N, Agudo-Conde C, Castano-Sanchez C, et al. Effectiveness of a multifactorial intervention based on an application for smartphones, heart-healthy walks and a nutritional workshop in patients with type 2 diabetes mellitus in primary care (EMID): study protocol for a randomised controlled trial. BMJ Open. 2017;7(9):e016191. https://doi.org/10.1136/bmjopen-2017-016191.CrossRefPubMedPubMedCentral

20.

Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes. 2003;52(1):1–8. https://doi.org/10.2337/diabetes.52.1.1.CrossRefPubMed

21.

Chrysohoou C, Panagiotakos DB, Pitsavos C, Das UN, Stefanadis C. Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: the ATTICA Study. J Am Coll Cardiol. 2004;44(1):152–8. https://doi.org/10.1016/j.jacc.2004.03.039.CrossRefPubMed

22.

Schulze MB, Hoffmann K, Manson JE, Willett WC, Meigs JB, Weikert C, et al. Dietary pattern, inflammation, and incidence of type 2 diabetes in women. Am J Clin Nutr. 2005;82(3):675–84; quiz 714-5. https://doi.org/10.1093/ajcn.82.3.675.CrossRefPubMed

23.

Giugliano D, Esposito K. Mediterranean diet and metabolic diseases. Curr Opin Lipidol. 2008;19(1):63–8. https://doi.org/10.1097/MOL.0b013e3282f2fa4d.CrossRefPubMed

24.

Salas-Salvado J, Guasch-Ferre M, Lee CH, Estruch R, Clish CB, Ros E. Protective effects of the Mediterranean diet on type 2 diabetes and metabolic syndrome. J Nutr. 2015;146(4):920S–7S. https://doi.org/10.3945/jn.115.218487.CrossRefPubMed

25.

Chandalia M, Garg A, Lutjohann D, von Bergmann K, Grundy SM, Brinkley LJ. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med. 2000;342(19):1392–8. https://doi.org/10.1056/NEJM200005113421903.CrossRefPubMed

26.

Guasch-Ferre M, Merino J, Sun Q, Fito M, Salas-Salvado J. Dietary polyphenols, Mediterranean diet, prediabetes, and type 2 diabetes: a narrative review of the evidence. Oxidative Med Cell Longev. 2017;2017:6723931–16. https://doi.org/10.1155/2017/6723931.CrossRef

27.

Alcubierre N, Martinez-Alonso M, Valls J, Rubinat E, Traveset A, Hernandez M, et al. Relationship of the adherence to the Mediterranean diet with health-related quality of life and treatment satisfaction in patients with type 2 diabetes mellitus: a post-hoc analysis of a cross-sectional study. Health Qual Life Outcomes. 2016;14:69. https://doi.org/10.1186/s12955-016-0473-z.CrossRefPubMedPubMedCentral

28.

Palta P, Schneider AL, Biessels GJ, Touradji P, Hill-Briggs F. Magnitude of cognitive dysfunction in adults with type 2 diabetes: a meta-analysis of six cognitive domains and the most frequently reported neuropsychological tests within domains. J Int Neuropsychol Soc. 2014;20(3):278–91. https://doi.org/10.1017/S1355617713001483.CrossRefPubMedPubMedCentral

29.

Cheng G, Huang C, Deng H, Wang H. Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies. Intern Med J. 2012;42(5):484–91. https://doi.org/10.1111/j.1445-5994.2012.02758.x.CrossRefPubMed

30.

Jayaraman A, Pike CJ. Alzheimer’s disease and type 2 diabetes: multiple mechanisms contribute to interactions. Curr Diab Rep. 2014;14(4):476. https://doi.org/10.1007/s11892-014-0476-2.CrossRefPubMedPubMedCentral

31.

Craft S. Insulin resistance and Alzheimer’s disease pathogenesis: potential mechanisms and implications for treatment. Curr Alzheimer Res. 2007;4(2):147–52. https://doi.org/10.2174/156720507780362137.CrossRefPubMed

32.

Ravona-Springer R, Schnaider-Beeri M. The association of diabetes and dementia and possible implications for nondiabetic populations. Expert Rev Neurother. 2011;11(11):1609–17. https://doi.org/10.1586/ern.11.152.CrossRefPubMedPubMedCentral

33.

Whitmer RA, Karter AJ, Yaffe K, Quesenberry CP Jr, Selby JV. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. Jama. 2009;301(15):1565–72. https://doi.org/10.1001/jama.2009.460.CrossRefPubMedPubMedCentral

34.

Biessels GJ, Despa F. Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications. Nat Rev Endocrinol. 2018;14(10):591–604. https://doi.org/10.1038/s41574-018-0048-7.CrossRefPubMedPubMedCentral

35.

• Scarmeas N, Anastasiou CA, Yannakoulia M. Nutrition and prevention of cognitive impairment. Lancet Neurol. 2018;17(11): 432 1006–15. https://doi.org/10.1016/S1474-4422(18)30338-7. An overview of the studies that evaluate the effect of nutrients and patterns on cognitive decline.

36.

•• Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, et al. Association of Mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis. 2014;39(2):271–82. https://doi.org/10.3233/JAD-130830. A nice paper on the potential mechanisms linking diabetes with cognitive dysfunction.

37.

Psaltopoulou T, Sergentanis TN, Panagiotakos DB, Sergentanis IN, Kosti R, Scarmeas N. Mediterranean diet, stroke, cognitive impairment, and depression: a meta-analysis. Ann Neurol. 2013;74(4):580–91. https://doi.org/10.1002/ana.23944.CrossRefPubMed

38.

Lehert P, Villaseca P, Hogervorst E, Maki PM, Henderson VW. Individually modifiable risk factors to ameliorate cognitive aging: a systematic review and meta-analysis. Climacteric. 2015;18(5):678–89. https://doi.org/10.3109/13697137.2015.1078106.CrossRefPubMedPubMedCentral

39.

Tsivgoulis G, Judd S, Letter AJ, Alexandrov AV, Howard G, Nahab F, et al. Adherence to a Mediterranean diet and risk of incident cognitive impairment. Neurology. 2013;80(18):1684–92. https://doi.org/10.1212/WNL.0b013e3182904f69.CrossRefPubMedPubMedCentral

40.

Hughes G, Bennett KM, Hetherington MM. Old and alone: barriers to healthy eating in older men living on their own. Appetite. 2004;43(3):269–76. https://doi.org/10.1016/j.appet.2004.06.002.CrossRefPubMed

41.

Lara J, McCrum LA, Mathers JC. Association of Mediterranean diet and other health behaviours with barriers to healthy eating and perceived health among British adults of retirement age. Maturitas. 2014;79(3):292–8. https://doi.org/10.1016/j.maturitas.2014.07.003.CrossRefPubMed

42.

Magkos F, Yannakoulia M, Chan JL, Mantzoros CS. Management of the metabolic syndrome and type 2 diabetes through lifestyle modification. Annu Rev Nutr. 2009;29:223–56. https://doi.org/10.1146/annurev-nutr-080508-141200.CrossRefPubMedPubMedCentral

Titel: Type 2 Diabetes and Mediterranean Diet in Older Adults: a Brief Review of the Evidence
verfasst von: Eirini Mamalaki
Vassilis Balomenos
Nikolaos Scarmeas
Mary Yannakoulia
Publikationsdatum: 18.11.2020
Verlag: Springer US
Erschienen in: Current Geriatrics Reports / Ausgabe 4/2020
Elektronische ISSN: 2196-7865
DOI: https://doi.org/10.1007/s13670-020-00340-8

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Abstract

Purpose of Review

Recent Findings

Summary

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