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16.02.2022 | Nuclear Cardiology (V Dilsizian, Section Editor)

Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)

verfasst von: Philip M. Parel, Alexander R. Berg, Christin G. Hong, Elizabeth M. Florida, Ross O’Hagan, Alexander V. Sorokin, Nehal N. Mehta

Erschienen in: Current Cardiology Reports | Ausgabe 4/2022

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Abstract

Purpose of Review

In this review, we focus on the clinical and epidemiological studies pertaining to systemic and vascular inflammation by positron emission tomography (PET) in patients with chronic inflammatory conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), human immunodeficiency virus (HIV), and psoriasis to highlight the importance of chronic systemic inflammation on vascular inflammation by PET in these disease states.

Recent Findings

Recent clinical and translation advancements have demonstrated the durable relationship between chronic systemic inflammation and cardiovascular disease (CVD). In chronic inflammatory states, this relationship is robustly evident in the form of increased vascular inflammation, yet traditional risk estimates often underestimate the subclinical cardiovascular risk conferred by chronic inflammation. PET has emerged as a novel, non-invasive imaging modality capable of both quantifying the degree of systemic and vascular inflammation and detecting residual inflammation prior to cardiovascular events.

Summary

We begin by demonstrating the role of inflammation in the pathogenesis of atherosclerosis, discussing how PET has been utilized to measure systemic and vascular inflammation and their effect on subclinical atherosclerosis, and finally reviewing recent applications of PET in constructing improved risk stratification for patients at high risk for stroke and CVD.

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Titel: Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)
verfasst von: Philip M. Parel
Alexander R. Berg
Christin G. Hong
Elizabeth M. Florida
Ross O’Hagan
Alexander V. Sorokin
Nehal N. Mehta
Publikationsdatum: 16.02.2022
Verlag: Springer US
Erschienen in: Current Cardiology Reports / Ausgabe 4/2022
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI: https://doi.org/10.1007/s11886-022-01651-2

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Springer Medizin

Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)

Abstract

Purpose of Review

Recent Findings

Summary

Neu im Fachgebiet Kardiologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Adipositas-Medikament auch gegen Schlafapnoe wirksam

Komplette Revaskularisation bei Infarkt: Neue Studie setzt ein Fragezeichen

Update Kardiologie

Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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Contemporary Management of Abdominal Aortic Aneurysms

Use of Prolonged Cardiac Rhythm Monitoring to Identify Atrial Fibrillation After Cryptogenic Stroke

Strategies for Imaging Metabolic Remodeling of the Heart in Obesity and Heart Failure

Methods of Blood Pressure Measurement to Predict Hypertension-Related Cardiovascular Morbidity and Mortality

Is Sedentary Behavior a Novel Risk Factor for Cardiovascular Disease?

Radial Artery Access for Acute Coronary Syndromes: a Review of Current Evidence

Neu im Fachgebiet Kardiologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Adipositas-Medikament auch gegen Schlafapnoe wirksam

Komplette Revaskularisation bei Infarkt: Neue Studie setzt ein Fragezeichen

Update Kardiologie