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Erschienen in:

06.09.2022 | Review

Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury

verfasst von: Ron Wald, William Beaubien-Souligny, Rahul Chanchlani, Edward G. Clark, Javier A. Neyra, Marlies Ostermann, Samuel A. Silver, Suvi Vaara, Alexander Zarbock, Sean M. Bagshaw

Erschienen in: Intensive Care Medicine | Ausgabe 10/2022

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Abstract

Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until kidney function recovers. This review is intended to provide a comprehensive update on key aspects of RRT prescription and delivery to critically ill patients. Recently completed trials have enhanced the evidence base regarding several RRT practices, most notably the timing of RRT initiation and anticoagulation for continuous therapies. Better evidence is still needed to clarify several aspects of care including optimal targets for ultrafiltration and effective strategies for RRT weaning and discontinuation.

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Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, Goldstein SL, Cerda J, Chawla LS (2018) Global epidemiology and outcomes of acute kidney injury. Nat Rev Nephrol 14(10):607–625PubMedCrossRef

Bagshaw SM, Darmon M, Ostermann M, Finkelstein FO, Wald R, Tolwani AJ, Goldstein SL, Gattas DJ, Uchino S, Hoste EA, Gaudry S (2017) Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury. Intensive Care Med 43(6):841–854PubMedCrossRef

Zarbock A, Kellum JA, Schmidt C, Van Aken H, Wempe C, Pavenstadt H, Boanta A, Gerss J, Meersch M (2016) Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial. JAMA 315(20):2190–2199PubMedCrossRef

Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, Boyer A, Chevrel G, Lerolle N, Carpentier D, de Prost N, Lautrette A, Bretagnol A, Mayaux J, Nseir S, Megarbane B, Thirion M, Forel JM, Maizel J, Yonis H, Markowicz P, Thiery G, Tubach F, Ricard JD, Dreyfuss D, Group AS (2016) Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med 375(2):122–133CrossRef

Barbar SD, Clere-Jehl R, Bourredjem A, Hernu R, Montini F, Bruyere R, Lebert C, Bohe J, Badie J, Eraldi JP, Rigaud JP, Levy B, Siami S, Louis G, Bouadma L, Constantin JM, Mercier E, Klouche K, du Cheyron D, Piton G, Annane D, Jaber S, van der Linden T, Blasco G, Mira JP, Schwebel C, Chimot L, Guiot P, Nay MA, Meziani F, Helms J, Roger C, Louart B, Trusson R, Dargent A, Binquet C, Quenot JP, Investigators I-IT, the CTN (2018) Timing of renal-replacement therapy in patients with acute kidney injury and sepsis. N Engl J Med 379(15):1431–1442PubMedCrossRef

Investigators T-AKI, Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann M, Palevsky PM, Pettila V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thome F, Thorpe KE, Vaara S, Weir M, Wang AY, Young P, Zarbock A (2020) Timing of initiation of renal-replacement therapy in acute kidney injury. N Engl J Med 383(3):240–251CrossRef

Gaudry S, Hajage D, Martin-Lefevre L, Lebbah S, Louis G, Moschietto S, Titeca-Beauport D, Combe B, Pons B, de Prost N, Besset S, Combes A, Robine A, Beuzelin M, Badie J, Chevrel G, Bohe J, Coupez E, Chudeau N, Barbar S, Vinsonneau C, Forel JM, Thevenin D, Boulet E, Lakhal K, Aissaoui N, Grange S, Leone M, Lacave G, Nseir S, Poirson F, Mayaux J, Asehnoune K, Geri G, Klouche K, Thiery G, Argaud L, Rozec B, Cadoz C, Andreu P, Reignier J, Ricard JD, Quenot JP, Dreyfuss D (2021) Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial. Lancet 397(10281):1293–1300PubMedCrossRef

Klein SJ, Brandtner AK, Lehner GF, Ulmer H, Bagshaw SM, Wiedermann CJ, Joannidis M (2018) Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis. Intensive Care Med 44(3):323–336PubMedPubMedCentralCrossRef

Hoste E, Bihorac A, Al-Khafaji A, Ortega LM, Ostermann M, Haase M, Zacharowski K, Wunderink R, Heung M, Lissauer M, Self WH, Koyner JL, Honore PM, Prowle JR, Joannidis M, Forni LG, Kampf JP, McPherson P, Kellum JA, Chawla LS (2020) Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study. Intensive Care Med 46(5):943–953PubMedPubMedCentralCrossRef

10.

Bagshaw SM, Al-Khafaji A, Artigas A, Davison D, Haase M, Lissauer M, Zacharowski K, Chawla LS, Kwan T, Kampf JP, McPherson P, Kellum JA (2021) External validation of urinary C-C motif chemokine ligand 14 (CCL14) for prediction of persistent acute kidney injury. Crit Care 25(1):185PubMedPubMedCentralCrossRef

11.

Chen JJ, Chang CH, Huang YT, Kuo G (2020) Furosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis. Crit Care 24(1):202PubMedPubMedCentralCrossRef

12.

Edrees F, Li T, Vijayan A (2016) Prolonged intermittent renal replacement therapy. Adv Chronic Kidney Dis 23(3):195–202PubMedCrossRef

13.

Phu NH, Hien TT, Mai NT, Chau TT, Chuong LV, Loc PP, Winearls C, Farrar J, White N, Day N (2002) Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam. N Engl J Med 347(12):895–902PubMedCrossRef

14.

Fisher R, Clarke J, Al-Arfi K, Saha R, Lioudaki E, Mehta R, Pahl C, Sharpe C, Bramham K, Hutchings S (2021) Provision of acute renal replacement therapy, using three separate modalities, in critically ill patients during the COVID-19 pandemic. An after action review from a UK tertiary critical care centre. J Crit Care 62:190–196PubMedCrossRef

15.

Zhou X, Dong P, Pan J, Wang H, Xu Z, Chen B (2021) Renal replacement therapy modality in critically ill patients with acute kidney injury—a network meta-analysis of randomized controlled trials. J Crit Care 64:82–90PubMedCrossRef

16.

Panaput T, Peerapornratana S, Sirivongrangson P, Kulvichit W, Lumlertgul N, Jonny J, Praditpornsilpa K, Tungsanga K, Eiam-Ong S, Srisawat N (2021) Modalities of renal replacement therapy and clinical outcomes of patients with acute kidney injury in a resource-limited setting: results from a SEA-AKI study. J Crit Care 65:18–25PubMedCrossRef

17.

Matsuura R, Doi K, Hamasaki Y, Nangaku M (2020) RRT selection for AKI patients with critical illness. Semin Nephrol 40(5):498–505

18.

Truche AS, Darmon M, Bailly S, Clec’h C, Dupuis C, Misset B, Azoulay E, Schwebel C, Bouadma L, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Zaoui P, Laurent V, Goldgran-Toledano D, Sonneville R, Souweine B, Timsit JF, Group OS (2016) Continuous renal replacement therapy versus intermittent hemodialysis in intensive care patients: impact on mortality and renal recovery. Intensive Care Med 42(9):1408–1417CrossRef

19.

Schneider AG, Bellomo R, Bagshaw SM, Glassford NJ, Lo S, Jun M, Cass A, Gallagher M (2013) Choice of renal replacement therapy modality and dialysis dependence after acute kidney injury: a systematic review and meta-analysis. Intensive Care Med 39(6):987–997PubMedCrossRef

20.

Zhang L, Yang J, Eastwood GM, Zhu G, Tanaka A, Bellomo R (2015) Extended daily dialysis versus continuous renal replacement therapy for acute kidney injury: a meta-analysis. Am J Kidney Dis 66(2):322–330PubMedCrossRef

21.

Liang KV, Sileanu FE, Clermont G, Murugan R, Pike F, Palevsky PM, Kellum JA (2016) Modality of RRT and recovery of kidney function after AKI in patients surviving to hospital discharge. Clin J Am Soc Nephrol 11(1):30–38PubMedCrossRef

22.

Gaudry S, Palevsky PM, Dreyfuss D (2022) Extracorporeal kidney-replacement therapy for acute kidney injury. N Engl J Med 386(10):964–975PubMedCrossRef

23.

Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294(7):813–818PubMedCrossRef

24.

Ostermann M, Bellomo R, Burdmann EA, Doi K, Endre ZH, Goldstein SL, Kane-Gill SL, Liu KD, Prowle JR, Shaw AD, Srisawat N, Cheung M, Jadoul M, Winkelmayer WC, Kellum JA, Conference P (2020) Controversies in acute kidney injury: conclusions from a Kidney Disease: improving Global Outcomes (KDIGO) Conference. Kidney Int 98(2):294–309

25.

Beaubien-Souligny W, Yang Y, Burns KEA, Friedrich JO, Meraz-Munoz A, Clark EG, Adhikari NK, Bagshaw SM, Wald R (2021) Intra-dialytic hypotension following the transition from continuous to intermittent renal replacement therapy. Ann Intensive Care 11(1):96PubMedPubMedCentralCrossRef

26.

Douvris A, Zeid K, Hiremath S, Bagshaw SM, Wald R, Beaubien-Souligny W, Kong J, Ronco C, Clark EG (2019) Mechanisms for hemodynamic instability related to renal replacement therapy: a narrative review. Intensive Care Med 45(10):1333–1346PubMedPubMedCentralCrossRef

27.

Silversides JA, Pinto R, Kuint R, Wald R, Hladunewich MA, Lapinsky SE, Adhikari NK (2014) Fluid balance, intradialytic hypotension, and outcomes in critically ill patients undergoing renal replacement therapy: a cohort study. Crit Care 18(6):624PubMedPubMedCentralCrossRef

28.

Mahmoud H, Forni LG, McIntyre CW, Selby NM (2017) Myocardial stunning occurs during intermittent haemodialysis for acute kidney injury. Intensive Care Med 43(6):942–944PubMedPubMedCentralCrossRef

29.

Slessarev M, Salerno F, Ball IM, McIntyre CW (2019) Continuous renal replacement therapy is associated with acute cardiac stunning in critically ill patients. Hemodial Int

30.

Douvris A, Malhi G, Hiremath S, McIntyre L, Silver SA, Bagshaw SM, Wald R, Ronco C, Sikora L, Weber C, Clark EG (2018) Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review. Crit Care 22(1):41PubMedPubMedCentralCrossRef

31.

Macedo E, Karl B, Lee E, Mehta RL (2021) A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients. Crit Care 25(1):18PubMedPubMedCentralCrossRef

32.

Clark EG, McIntyre L, Watpool I, Kong JWY, Ramsay T, Sabri E, Canney M, Hundemer GL, Brown PA, Sood MM, Hiremath S (2021) Intravenous albumin for the prevention of hemodynamic instability during sustained low-efficiency dialysis: a randomized controlled feasibility trial (The SAFER-SLED Study). Ann Intensive Care 11(1):174PubMedPubMedCentralCrossRef

33.

Bonavia A, Miller L, Kellum JA, Singbartl K (2017) Hemoadsorption corrects hyperresistinemia and restores anti-bacterial neutrophil function. Intensive Care Med Exp 5(1):36PubMedPubMedCentralCrossRef

34.

Cole L, Bellomo R, Journois D, Davenport P, Baldwin I, Tipping P (2001) High-volume haemofiltration in human septic shock. Intensive Care Med 27(6):978–986PubMedCrossRef

35.

Chung KK, Coates EC, Smith DJ Jr, Karlnoski RA, Hickerson WL, Arnold-Ross AL, Mosier MJ, Halerz M, Sprague AM, Mullins RF, Caruso DM, Albrecht M, Arnoldo BD, Burris AM, Taylor SL, Wolf SE (2017) High-volume hemofiltration in adult burn patients with septic shock and acute kidney injury: a multicenter randomized controlled trial. Crit Care 21(1):289PubMedPubMedCentralCrossRef

36.

Wald R, Friedrich JO, Bagshaw SM, Burns KE, Garg AX, Hladunewich MA, House AA, Lapinsky S, Klein D, Pannu NI, Pope K, Richardson RM, Thorpe K, Adhikari NK (2012) Optimal Mode of clearance in critically ill patients with Acute Kidney Injury (OMAKI)—a pilot randomized controlled trial of hemofiltration versus hemodialysis: a Canadian Critical Care Trials Group project. Crit Care 16(5):R205PubMedPubMedCentralCrossRef

37.

Clark E, Molnar AO, Joannes-Boyau O, Honoré PM, Sikora L, Bagshaw SM (2014) High-volume hemofiltration for septic acute kidney injury: a systematic review and meta-analysis. Crit Care 18(1):R7PubMedPubMedCentralCrossRef

38.

Borthwick EM, Hill CJ, Rabindranath KS, Maxwell AP, McAuley DF, Blackwood B (2017) High-volume haemofiltration for sepsis in adults. Cochrane Database Syst Rev 1(1):Cd008075

39.

Côté JM, Pinard L, Cailhier JF, Lévesque R, Murray PT, Beaubien-Souligny W (2022) Intermittent convective therapies in patients with acute kidney injury: a systematic review with meta-analysis. Blood Purif 51(1):75–86PubMedCrossRef

40.

Broman ME, Hansson F, Vincent JL, Bodelsson M (2019) Endotoxin and cytokine reducing properties of the oXiris membrane in patients with septic shock: a randomized crossover double-blind study. PLoS ONE 14(8):e0220444PubMedPubMedCentralCrossRef

41.

Malard B, Lambert C, Kellum JA (2018) In vitro comparison of the adsorption of inflammatory mediators by blood purification devices. Intensive Care Med Exp 6(1):12PubMedPubMedCentralCrossRef

42.

Garbero E, Livigni S, Ferrari F, Finazzi S, Langer M, Malacarne P, Meca MCC, Mosca S, Olivieri C, Pozzato M, Rossi C, Tavola M, Terzitta M, Viaggi B, Bertolini G (2021) High dose coupled plasma filtration and adsorption in septic shock patients. Results of the COMPACT-2: a multicentre, adaptive, randomised clinical trial. Intensive Care Med 47(11):1303–1311

43.

Putzu A, Schorer R, Lopez-Delgado JC, Cassina T, Landoni G (2019) Blood purification and mortality in sepsis and septic shock: a systematic review and meta-analysis of randomized trials. Anesthesiology 131(3):580–593PubMedCrossRef

44.

Nih Acute Renal Failure Trial Network VA, Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359(1):7–20CrossRef

45.

RENAL Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S (2009) Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 361(17):1627–1638CrossRef

46.

Rosner MH, Connor MJ Jr (2018) Management of severe hyponatremia with continuous renal replacement therapies. Clin J Am Soc Nephrol 13(5):787–789PubMedPubMedCentralCrossRef

47.

Ostermann M, Dickie H, Tovey L, Treacher D (2010) Management of sodium disorders during continuous haemofiltration. Crit Care 14(3):418PubMedPubMedCentralCrossRef

48.

Yessayan L, Yee J, Frinak S, Szamosfalvi B (2014) Treatment of severe hyponatremia in patients with kidney failure: role of continuous venovenous hemofiltration with low-sodium replacement fluid. Am J Kidney Dis 64(2):305–310PubMedCrossRef

49.

Neyra JA, Ortiz-Soriano VM, Ali D, Morris PE, Johnston CM (2019) A multidisciplinary approach for the management of severe hyponatremia in patients requiring continuous renal replacement therapy. Kidney Int Rep 4(1):59–66PubMedCrossRef

50.

Demirjian S, Teo BW, Guzman JA, Heyka RJ, Paganini EP, Fissell WH, Schold JD, Schreiber MJ (2011) Hypophosphatemia during continuous hemodialysis is associated with prolonged respiratory failure in patients with acute kidney injury. Nephrol Dial Transpl 26(11):3508–3514CrossRef

51.

Thompson Bastin ML, Adams PM, Nerusu S, Morris PE, Mayer KP, Neyra JA (2022) Association of phosphate containing solutions with incident hypophosphatemia in critically ill patients requiring continuous renal replacement therapy. Blood Purif 51(2):122–129PubMedCrossRef

52.

Thompson Bastin ML, Stromberg AJ, Nerusu SN, Liu LJ, Mayer KP, Liu KD, Bagshaw SM, Wald R, Morris PE, Neyra JA (2022) Association of phosphate-containing versus phosphate-free solutions on ventilator days in patients requiring continuous kidney replacement therapy. Clin J Am Soc Nephrol

53.

Coutrot M, Hekimian G, Moulin T, Brechot N, Schmidt M, Besset S, Nieszkowska A, Franchineau G, Bourcier S, Bourron O, Luyt CE, Combes A (2018) Euglycemic ketoacidosis, a common and underecognized complication of continuous renal replacement therapy using glucose-free solutions. Intensive Care Med 44(7):1185–1186PubMedCrossRef

54.

Ting S, Chua HR, Cove ME (2021) Euglycemic ketosis during continuous kidney replacement therapy with glucose-free solution: a report of 8 cases. Am J Kidney Dis 78(2):305–308PubMedCrossRef

55.

Stevens JS, Salazar-Schicchi J, Radhakrishnan J, Mohan S (2021) The case|euglycemic ketoacidosis in a patient on continuous renal replacement therapy. Kidney Int 99(6):1507–1508PubMedCrossRef

56.

Tolwani AJ, Prendergast MB, Speer RR, Stofan BS, Wille KM (2006) A practical citrate anticoagulation continuous venovenous hemodiafiltration protocol for metabolic control and high solute clearance. Clin J Am Soc Nephrol 1(1):79–87PubMedCrossRef

57.

Tsujimoto H, Tsujimoto Y, Nakata Y, Fujii T, Takahashi S, Akazawa M, Kataoka Y (2020) Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy. Cochrane Database Syst Rev 12:CD012467

58.

Zarbock A, Kullmar M, Kindgen-Milles D, Wempe C, Gerss J, Brandenburger T, Dimski T, Tyczynski B, Jahn M, Mulling N, Mehrlander M, Rosenberger P, Marx G, Simon TP, Jaschinski U, Deetjen P, Putensen C, Schewe JC, Kluge S, Jarczak D, Slowinski T, Bodenstein M, Meybohm P, Wirtz S, Moerer O, Kortgen A, Simon P, Bagshaw SM, Kellum JA, Meersch M, Investigators R, the Sepnet Trial G, (2020) Effect of regional citrate anticoagulation vs systemic heparin anticoagulation during continuous kidney replacement therapy on dialysis filter life span and mortality among critically ill patients with acute kidney injury: a randomized clinical trial. JAMA 324(16):1629–1639PubMedCrossRef

59.

Slowinski T, Morgera S, Joannidis M, Henneberg T, Stocker R, Helset E, Andersson K, Wehner M, Kozik-Jaromin J, Brett S, Hasslacher J, Stover JF, Peters H, Neumayer HH, Kindgen-Milles D (2015) Safety and efficacy of regional citrate anticoagulation in continuous venovenous hemodialysis in the presence of liver failure: the Liver Citrate Anticoagulation Threshold (L-CAT) observational study. Crit Care 19:349PubMedPubMedCentralCrossRef

60.

Klingele M, Stadler T, Fliser D, Speer T, Groesdonk HV, Raddatz A (2017) Long-term continuous renal replacement therapy and anticoagulation with citrate in critically ill patients with severe liver dysfunction. Crit Care 21(1):294PubMedPubMedCentralCrossRef

61.

Malbrain M, Van Regenmortel N, Saugel B, De Tavernier B, Van Gaal PJ, Joannes-Boyau O, Teboul JL, Rice TW, Mythen M, Monnet X (2018) Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy. Ann Intensive Care 8(1):66PubMedPubMedCentralCrossRef

62.

Messmer AS, Zingg C, Müller M, Gerber JL, Schefold JC, Pfortmueller CA (2020) Fluid overload and mortality in adult critical care patients—a systematic review and meta-analysis of observational studies. Crit Care Med 48(12):1862–1870PubMedCrossRef

63.

Woodward CW, Lambert J, Ortiz-Soriano V, Li Y, Ruiz-Conejo M, Bissell BD, Kelly A, Adams P, Yessayan L, Morris PE, Neyra JA (2019) Fluid overload associates with major adverse kidney events in critically ill patients with acute kidney injury requiring continuous renal replacement therapy. Crit Care Med 47(9):e753–e760PubMedCrossRef

64.

Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lee J, Lo S, McArthur C, McGuiness S, Norton R, Myburgh J, Scheinkestel C, Su S (2012) An observational study fluid balance and patient outcomes in the Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy trial. Crit Care Med 40(6):1753–1760

65.

Murugan R, Kerti SJ, Chang CH, Gallagher M, Clermont G, Palevsky PM, Kellum JA, Bellomo R (2019) Association of net ultrafiltration rate with mortality among critically ill adults with acute kidney injury receiving continuous venovenous hemodiafiltration: a secondary analysis of the randomized evaluation of normal vs augmented level (RENAL) of renal replacement therapy trial. JAMA Netw Open 2(6):e195418PubMedPubMedCentralCrossRef

66.

Katulka RJ, Al Saadon A, Sebastianski M, Featherstone R, Vandermeer B, Silver SA, Gibney RTN, Bagshaw SM, Rewa OG (2020) Determining the optimal time for liberation from renal replacement therapy in critically ill patients: a systematic review and meta-analysis (DOnE RRT). Crit Care 24(1):50PubMedPubMedCentralCrossRef

67.

Baeg SI, Jeon J, Yoo H, Na SJ, Kim K, Chung CR, Yang JH, Jeon K, Lee JE, Huh W, Suh GY, Kim YG, Kim DJ, Jang HR (2021) A scoring model with simple clinical parameters to predict successful discontinuation of continuous renal replacement therapy. Blood Purif 50(6):779–789PubMedCrossRef

68.

Liu C, Peng Z, Dong Y, Li Z, Andrijasevic NM, Albright RC Jr, Kashani KB (2021) Predicting successful continuous renal replacement therapy liberation in critically ill patients with acute kidney injury. J Crit Care 66:6–13PubMedCrossRef

69.

Chanchlani R, Nash DM, McArthur E, Zappitelli M, Archer V, Kuwornu JP, Garg AX, Greenberg JH, Goldstein SL, Thabane L, Wald R (2019) Secular trends in incidence, modality and mortality with dialysis receiving AKI in children in Ontario: a population-based cohort study. Clin J Am Soc Nephrol 14(9):1288–1296PubMedPubMedCentralCrossRef

70.

Robinson CH, Jeyakumar N, Luo B, Wald R, Garg AX, Nash DM, McArthur E, Greenberg JH, Askenazi D, Mammen C, Thabane L, Goldstein S, Parekh RS, Zappitelli M, Chanchlani R (2021) Long-term kidney outcomes following dialysis-treated childhood acute kidney injury: a population-based cohort study. J Am Soc Nephrol 32(8):2005–2019PubMedPubMedCentralCrossRef

71.

Mammen C, Al Abbas A, Skippen P, Nadel H, Levine D, Collet JP, Matsell DG (2012) Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study. Am J Kidney Dis 59(4):523–530PubMedCrossRef

72.

Hessey E, Morissette G, Lacroix J, Perreault S, Samuel S, Dorais M, Phan V, Jouvet P, Lafrance JP, LeLorier J, Palijan A, Pizzi M, Roy L, Zappitelli M (2018) Healthcare utilization after acute kidney injury in the pediatric intensive care unit. Clin J Am Soc Nephrol 13(5):685–692PubMedPubMedCentralCrossRef

73.

Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL (2017) Epidemiology of acute kidney injury in critically ill children and young adults. N Engl J Med 376(1):11–20PubMedCrossRef

74.

Li S, Krawczeski CD, Zappitelli M, Devarajan P, Thiessen-Philbrook H, Coca SG, Kim RW, Parikh CR (2011) Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study. Crit Care Med 39(6):1493–1499PubMedPubMedCentralCrossRef

75.

Morgan CJ, Zappitelli M, Robertson CM, Alton GY, Sauve RS, Joffe AR, Ross DB, Rebeyka IM (2013) Risk factors for and outcomes of acute kidney injury in neonates undergoing complex cardiac surgery. J Pediatr 162(1):120-127.e121PubMedCrossRef

76.

Jetton JG, Boohaker LJ, Sethi SK, Wazir S, Rohatgi S, Soranno DE, Chishti AS, Woroniecki R, Mammen C, Swanson JR, Sridhar S, Wong CS, Kupferman JC, Griffin RL, Askenazi DJ (2017) Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study. Lancet Child Adolesc Health 1(3):184–194PubMedPubMedCentralCrossRef

77.

Starr MC, Charlton JR, Guillet R, Reidy K, Tipple TE, Jetton JG, Kent AL, Abitbol CL, Ambalavanan N, Mhanna MJ, Askenazi DJ, Selewski DT, Harer MW (2021) Advances in neonatal acute kidney injury. Pediatrics 148(5)

78.

Askenazi D, Ingram D, White S, Cramer M, Borasino S, Coghill C, Dill L, Tenney F, Feig D, Fathallah-Shaykh S (2016) Smaller circuits for smaller patients: improving renal support therapy with Aquadex™. Pediatr Nephrol 31(5):853–860PubMedCrossRef

79.

Reznik VM, Randolph G, Collins CM, Peterson BM, Lemire JM, Mendoza SA (1993) Cost analysis of dialysis modalities for pediatric acute renal failure. Perit Dial Int 13(4):311–313PubMedCrossRef

80.

Flynn JT (2002) Choice of dialysis modality for management of pediatric acute renal failure. Pediatr Nephrol 17(1):61–69PubMedCrossRef

81.

Burgmaier K, Hackl A, Ehren R, Kribs A, Burgmaier M, Weber LT, Oberthuer A, Habbig S (2020) Peritoneal dialysis in extremely and very low-birth-weight infants. Perit Dial Int 40(2):233–236PubMedCrossRef

82.

Stojanović VD, Bukarica SS, Antić JB, Doronjski AD (2017) Peritoneal dialysis in very low birth weight neonates. Perit Dial Int 37(4):389–396PubMedCrossRef

83.

Barhight MF, Soranno D, Faubel S, Gist KM (2018) Fluid management with peritoneal dialysis after pediatric cardiac surgery. World J Pediatr Congenit Heart Surg 9(6):696–704PubMedCrossRef

84.

Guzzo I, de Galasso L, Mir S, Bulut IK, Jankauskiene A, Burokiene V, Cvetkovic M, Kostic M, Bayazit AK, Yildizdas D, Schmitt CP, Paglialonga F, Montini G, Yilmaz E, Oh J, Weber L, Taylan C, Hayes W, Shroff R, Vidal E, Murer L, Mencarelli F, Pasini A, Teixeira A, Afonso AC, Drozdz D, Schaefer F, Picca S (2019) Acute dialysis in children: results of a European survey. J Nephrol 32(3):445–451PubMedCrossRef

85.

Nourse P, Cullis B, Finkelstein F, Numanoglu A, Warady B, Antwi S, McCulloch M (2021) ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 Update (paediatrics). Perit Dial Int 41(2):139–157PubMedCrossRef

86.

Ansari N (2011) Peritoneal dialysis in renal replacement therapy for patients with acute kidney injury. Int J Nephrol 2011:739794PubMedPubMedCentralCrossRef

87.

Vasudevan A, Phadke K, Yap HK (2017) Peritoneal dialysis for the management of pediatric patients with acute kidney injury. Pediatr Nephrol 32(7):1145–1156PubMedCrossRef

88.

Agrawal A, Nolph KD (2000) Advantages of tidal peritoneal dialysis. Perit Dial Int 20(Suppl 2):S98-100PubMedCrossRef

89.

Gabriel DP, Nascimento GV, Caramori JT, Martim LC, Barretti P, Balbi AL (2007) High volume peritoneal dialysis for acute renal failure. Perit Dial Int 27(3):277–282PubMedCrossRef

90.

Raaijmakers R, Schröder CH, Gajjar P, Argent A, Nourse P (2011) Continuous flow peritoneal dialysis: first experience in children with acute renal failure. Clin J Am Soc Nephrol 6(2):311–318PubMedPubMedCentralCrossRef

91.

HK Yap LR. Peritoneal dialysis in critically ill children. . In: Goldstein ADaSL, ed. Critical care nephrology and renal replacement therapy in children. Springer; 2018.

92.

Raina R, McCulloch M, Nourse P, Sethi SK, Yap HK (2021) Advances in kidney replacement therapy in infants. Adv Chronic Kidney Dis 28(1):91–104PubMedCrossRef

93.

Munshi R, Lee-Son K, Hackbarth RM, Quigley R, Sutherland SM, Echeverri J, Goldstein SL (2020) Clinical evaluation of the Prismaflex™ HF 20 set and Prismaflex™ system 7.10 for acute continuous kidney replacement therapy (CKRT) in children. Pediatr Nephrol 35(12):2345–2352

94.

Liu ID, Ng KH, Lau PY, Yeo WS, Koh PL, Yap HK (2013) Use of HF20 membrane in critically ill unstable low-body-weight infants on inotropic support. Pediatr Nephrol 28(5):819–822PubMedCrossRef

95.

Santiago MJ, López-Herce J (2011) Prismaflex HF20 for continuous renal replacement therapy in critically ill children. Artif Organs 35(12):1194PubMedCrossRef

96.

Vidal E, Garzotto F, Parolin M, Manenti C, Zanin A, Bellettato M, Remuzzi G, Goldstein SL, Murer L, Ronco C (2017) Therapeutic plasma exchange in neonates and infants: successful use of a miniaturized machine. Blood Purif 44(2):100–105PubMedCrossRef

97.

Garzotto F, Vidal E, Ricci Z, Paglialonga F, Giordano M, Laforgia N, Peruzzi L, Bellettato M, Murer L, Ronco C (2020) Continuous kidney replacement therapy in critically ill neonates and infants: a retrospective analysis of clinical results with a dedicated device. Pediatr Nephrol 35(9):1699–1705PubMedCrossRef

98.

Goldstein SL, Vidal E, Ricci Z, Paglialonga F, Peruzzi L, Giordano M, Laforgia N, Ronco C (2022) Survival of infants treated with CKRT: comparing adapted adult platforms with the Carpediem™. Pediatr Nephrol 37(3):667–675PubMedCrossRef

99.

Menon S, Broderick J, Munshi R, Dill L, DePaoli B, Fathallah-Shaykh S, Claes D, Goldstein SL, Askenazi DJ (2019) Kidney support in children using an ultrafiltration device: a multicenter, retrospective study. Clin J Am Soc Nephrol 14(10):1432–1440PubMedPubMedCentralCrossRef

100.

Coulthard MG, Crosier J, Griffiths C, Smith J, Drinnan M, Whitaker M, Beckwith R, Matthews JN, Flecknell P, Lambert HJ (2014) Haemodialysing babies weighing <8 kg with the Newcastle infant dialysis and ultrafiltration system (Nidus): comparison with peritoneal and conventional haemodialysis. Pediatr Nephrol 29(10):1873–1881PubMedPubMedCentralCrossRef

Titel: Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury
verfasst von: Ron Wald
William Beaubien-Souligny
Rahul Chanchlani
Edward G. Clark
Javier A. Neyra
Marlies Ostermann
Samuel A. Silver
Suvi Vaara
Alexander Zarbock
Sean M. Bagshaw
Publikationsdatum: 06.09.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 10/2022
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-022-06851-6

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