Introduction
Materials and methods
Subjects
Piglets
Babies
Adult volunteer
Dialysis methods
The Nidus
Peritoneal dialysis
Assessments
Chemical clearance measurements
Ultrafiltration measurements—direct
Ultrafiltration measurements—indirect
Statistical analysis
Results
Subjects studied
Piglets
Babies
Case | Sex | Age (days) | Weight (kg) | Cause of renal failure | Prior ECMO | Reason for using haemodialysis and/ or PD | Haemodialysis | PD hourly dialysate flow | |
---|---|---|---|---|---|---|---|---|---|
Sessions | Hours | (ml/kg) | |||||||
1 | Male | 3 | 1.8 | ESRF, solitary MCD | Had colostomy for anal atresia | 163 | 847 | 21 | |
2 | Female | 58 | 3.3 | ESRF, bilateral MCD | Fungal peritonitis with initial PD | 11 | 66 | 28 | |
3 | Male | 6 | 3.5 | Post-cardiac surgery | RCT, but could not tolerate PD | 5 | 75 | 20 | |
4 | Female | 37 | 4.0 | SVT causing ESRF | + | Had colostomy for NEC | 158 | 1,236 | |
5 | Female | 6 | 4.1 | Meconium aspiration, PPHN | + | Had NEC with abdominal distension | 5 | 85 | |
6 | Female | 20 | 2.6 | TBM and post-cardiac surgery | + | Open chest and high IPPV pressures | 5 | 110 | |
7 | Female | 6 | 2.4 | Methyl-malonic acidaemia | PD inefficient for ammonia removal | 4 | 12 | ||
8 | Male | 349 | 7.0 | Post-cardiac surgery | + | Gut perforation with previous PD | 1 | 24 | |
9 | Male | 5 | 3.1 | Complex heart disease | Gut resection for NEC | 1 | 12 | ||
10 | Male | 27 | 4.0 | Post-cardiac surgery | + | Started on PD and recovered promptly | 0 | 0 | 20 |
11 | Male | 228 | 5.2 | ESRF, renal dysplasia | Temporary PD failure | 1 | 8 | 41 | |
Totals | 354 | 2,475 |