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European Radiology

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17.02.2022 | Imaging Informatics and Artificial Intelligence

Fully automated intracardiac 4D flow MRI post-processing using deep learning for biventricular segmentation

verfasst von: Philip A. Corrado, Andrew L. Wentland, Jitka Starekova, Archana Dhyani, Kara N. Goss, Oliver Wieben

Erschienen in: European Radiology | Ausgabe 8/2022

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Abstract

Objectives

4D flow MRI allows for a comprehensive assessment of intracardiac blood flow, useful for assessing cardiovascular diseases, but post-processing requires time-consuming ventricular segmentation throughout the cardiac cycle and is prone to subjective errors. Here, we evaluate the use of automatic left and right ventricular (LV and RV) segmentation based on deep learning (DL) network that operates on short-axis cine bSSFP images.

Methods

A previously published DL network was fine-tuned via retraining on a local database of 106 subjects scanned at our institution. In 26 test subjects, the ventricles were segmented automatically by the network and manually by 3 human observers on bSSFP MRI. The bSSFP images were then registered to the corresponding 4D flow images to apply the segmentation to 4D flow velocity data. Dice coefficients and the relative deviation between measurements (automatic vs. manual and interobserver manual) of various hemodynamic parameters were assessed.

Results

The automated segmentation resulted in similar Dice scores (LV: 0.92, RV: 0.86) and lower relative deviations from manual segmentation in left ventricular (LV) average kinetic energy (KE) (8%) and RV KE (15%) than the Dice scores (LV: 0.91, RV: 0.87) and relative deviations between manual segmentation observers (LV KE: 11%, p = 0.01; RV KE: 19%, p = 0.03).

Conclusions

The automated post-processing method using deep learning resulted in hemodynamic measurements that differ from a manual observer’s measurements equally or less than the variation between manual observers. This approach can be used to decrease post-processing time on intraventricular 4D flow data and mitigate interobserver variability.

Key Points

• Our proposed method allows for fully automated post-processing of intraventricular 4D flow MRI data.

• Our method resulted in hemodynamic measurements that matched those derived from manual segmentation equally as well as interobserver variability.

• Our method can be used to greatly accelerate intraventricular 4D flow post-processing and improve interobserver repeatability.

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Titel: Fully automated intracardiac 4D flow MRI post-processing using deep learning for biventricular segmentation
verfasst von: Philip A. Corrado
Andrew L. Wentland
Jitka Starekova
Archana Dhyani
Kara N. Goss
Oliver Wieben
Publikationsdatum: 17.02.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 8/2022
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-022-08616-7

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Fully automated intracardiac 4D flow MRI post-processing using deep learning for biventricular segmentation

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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Abstract

Objectives

Methods

Results

Conclusions

Key Points

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