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11.04.2024 | Neuropathischer Schmerz | Übersichten

Die EAN-NeuPSIG-Leitlinie zur Diagnostik bei neuropathischen Schmerzen – eine Kurzfassung

verfasst von: Prof. Dr. Claudia Sommer, Ralf Baron, Juliane Sachau, Aikaterini Papagianni, Özüm S. Özgül, Elena Enax-Krumova

Erschienen in: Der Schmerz

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Zusammenfassung

In dieser gemeinsamen Leitlinie der im Titel genannten Fachgesellschaften und Arbeitsgruppen wurden evidenzbasierte Empfehlungen für den Einsatz von Screening-Fragebögen und diagnostischen Tests bei Patienten mit neuropathischen Schmerzen entwickelt. Die systematische Literatursuche und Metaanalyse erbrachte folgende Ergebnisse: Von den Screening-Fragebögen erhielten Douleur Neuropathique en 4 Questions (DN4), I‑DN4 (Patientenversion DN4) und das Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) eine starke Empfehlung, und S‑LANSS (Patientenversion LANSS) und painDETECT schwache Empfehlungen für ihre Verwendung im Diagnosepfad für Patienten mit möglichem neuropathischem Schmerz. Es resultierte eine starke Empfehlung für die Verwendung einer Hautbiopsie und eine schwache Empfehlung für die quantitative sensorische Testung und nozizeptiv evozierte Potenziale. Der Stellenwert der konfokalen kornealen Mikroskopie ist noch offen. Funktionelle Bildgebung und periphere Nervenblockaden sind hilfreich bei der Aufklärung der Pathophysiologie, die aktuelle Literatur unterstützt ihre Verwendung zur Diagnose von neuropathischen Schmerzen jedoch nicht. In ausgewählten Fällen kann eine genetische Untersuchung in spezialisierten Zentren in Betracht gezogen werden.
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Metadaten
Titel
Die EAN-NeuPSIG-Leitlinie zur Diagnostik bei neuropathischen Schmerzen – eine Kurzfassung
verfasst von
Prof. Dr. Claudia Sommer
Ralf Baron
Juliane Sachau
Aikaterini Papagianni
Özüm S. Özgül
Elena Enax-Krumova
Publikationsdatum
11.04.2024
Verlag
Springer Medizin
Erschienen in
Der Schmerz
Print ISSN: 0932-433X
Elektronische ISSN: 1432-2129
DOI
https://doi.org/10.1007/s00482-024-00806-0

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