Skip to main content
Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 6/2017

01.06.2017 | Reports of Original Investigations

Predictors of intraoperative testing in adults undergoing noncardiac surgery within a regional hospital system

verfasst von: Jessica Spence, MD, Michael Troncone, MD, Steven Long, BSc, Velina Tzankova, MD, Susan Tran, MD, Joshua Peachey, MD, Yannick LeManach, MD, PhD, James Paul, MSc, MD, FRCPC

Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Ausgabe 6/2017

Einloggen, um Zugang zu erhalten

Abstract

Background

The use of intraoperative testing is central to anesthesia practice, and point-of-care testing (POCT) is often used. Nevertheless, POCT is costly and its contribution to patient outcome is unknown. There is a lack of guidelines to describe which patients should undergo intraoperative testing or how results should be applied. As such, we undertook a historical cohort study evaluating intraoperative testing practices within our region where POCT is not used.

Methods

In 2012, we obtained a random sample of 1,000 adult patients undergoing noncardiac surgery in three of our health system hospitals. Patient, surgical, and testing details were extracted, and the surgical procedures were categorized using the Johns Hopkins risk guidelines. Our primary outcome was the administration of at least one intraoperative test. We used a multivariable logistic regression model to identify factors associated with testing and described the time from ordering the tests to receiving the results using descriptive statistics.

Results

Study results showed that 110/1,000 (11.0%) patients underwent 413 diagnostic tests. Complete blood count was the most commonly administered test (36.3%), and the mean (standard deviation) time to obtain all test results was 29.9 (19.9) min. High-risk procedures were associated with an odds ratio (OR) of 12.3 (95% confidence interval [CI], 8.3 to 18.2; P < 0.001). Other predictors of intraoperative testing included emergency surgery (OR, 3.8; 95% CI, 2.0 to 7.2; P < 0.001), number of comorbidities (OR, 1.1; 95% CI, 1.0 to 1.2; P = 0.03), and duration of surgery (OR, 2.3; 95% CI, 1.8 to 2.9; P < 0.001).

Conclusion

Intraoperative testing is common and more likely in patients undergoing high-risk surgical procedures. In a central laboratory system, there is substantial time from ordering the tests to receiving the results. The clinical impact of this delay is unknown. Further evaluation is required regarding the relationship between the time required for intraoperative test results and perioperative outcomes.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Kost G. Principles & Practice of Point-of-Care Testing. Hagerstown, MD: Lippincott Williams & Wilkins; 2002 . Kost G. Principles & Practice of Point-of-Care Testing. Hagerstown, MD: Lippincott Williams & Wilkins; 2002 .
2.
Zurück zum Zitat Rhee AJ, Kahn RA. Laboratory point-of-care monitoring in the operating room. Curr Opin Anaesthesiol 2010; 23: 741-8.CrossRefPubMed Rhee AJ, Kahn RA. Laboratory point-of-care monitoring in the operating room. Curr Opin Anaesthesiol 2010; 23: 741-8.CrossRefPubMed
3.
Zurück zum Zitat Hildyard C, Curry N. Point-of-care testing: a standard of care? Anaesthesia 2015; 70: 1113-8.CrossRefPubMed Hildyard C, Curry N. Point-of-care testing: a standard of care? Anaesthesia 2015; 70: 1113-8.CrossRefPubMed
4.
Zurück zum Zitat Spence J, Bell DD, Garland A. Variation in diagnostic testing in ICUs: a comparison of teaching and nonteaching hospitals in a regional system. Crit Care Med 2014; 42: 9-16.CrossRefPubMed Spence J, Bell DD, Garland A. Variation in diagnostic testing in ICUs: a comparison of teaching and nonteaching hospitals in a regional system. Crit Care Med 2014; 42: 9-16.CrossRefPubMed
5.
Zurück zum Zitat Zimmerman JE, Seneff MG, Sun X, Wagner DP, Knaus WA. Evaluating laboratory usage in the intensive care unit: patient and institutional characteristics that influence frequency of blood sampling. Crit Care Med 1997; 25: 737-48.CrossRefPubMed Zimmerman JE, Seneff MG, Sun X, Wagner DP, Knaus WA. Evaluating laboratory usage in the intensive care unit: patient and institutional characteristics that influence frequency of blood sampling. Crit Care Med 1997; 25: 737-48.CrossRefPubMed
6.
Zurück zum Zitat von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007; 370: 1453-7.CrossRef von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007; 370: 1453-7.CrossRef
8.
Zurück zum Zitat Moons KG, Altman DG, Reitsma JB, et al. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med 2015; 162: W1-73.CrossRefPubMed Moons KG, Altman DG, Reitsma JB, et al. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med 2015; 162: W1-73.CrossRefPubMed
9.
Zurück zum Zitat Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement. J Clin Epidemiol 2015; 68: 134-43.CrossRefPubMed Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement. J Clin Epidemiol 2015; 68: 134-43.CrossRefPubMed
10.
Zurück zum Zitat Jaffe RA. Anesthesiologist’s Manual of Surgical Procedures. 5th ed. Philadelphia, PA: Wolters Kluwer Health; 2014 . Jaffe RA. Anesthesiologist’s Manual of Surgical Procedures. 5th ed. Philadelphia, PA: Wolters Kluwer Health; 2014 .
11.
Zurück zum Zitat Donati A, Ruzzi M, Adrario E, et al. A new and feasible model for predicting operative risk. Br J Anaesth 2004; 93: 393-9.CrossRefPubMed Donati A, Ruzzi M, Adrario E, et al. A new and feasible model for predicting operative risk. Br J Anaesth 2004; 93: 393-9.CrossRefPubMed
12.
Zurück zum Zitat Steyerberg EW, Eijkemans MJ, Harrell FE, Habbema JD. Prognostic modeling with logistic regression analysis: in search of a sensible strategy in small data sets. Med Decis Making 2001; 21: 45-56.CrossRefPubMed Steyerberg EW, Eijkemans MJ, Harrell FE, Habbema JD. Prognostic modeling with logistic regression analysis: in search of a sensible strategy in small data sets. Med Decis Making 2001; 21: 45-56.CrossRefPubMed
13.
Zurück zum Zitat Derksen S, Keselman HJ. Backward, forward and stepwise automated subset selection algorithms: frequency of obtaining authentic and noise variables. Br J Math Stat Psychol 1992; 45: 265-82.CrossRef Derksen S, Keselman HJ. Backward, forward and stepwise automated subset selection algorithms: frequency of obtaining authentic and noise variables. Br J Math Stat Psychol 1992; 45: 265-82.CrossRef
14.
Zurück zum Zitat Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996; 15: 361-87.CrossRefPubMed Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996; 15: 361-87.CrossRefPubMed
15.
Zurück zum Zitat Collins GS, Ogundimu EO, Cook JA, Manach YL, Altman DG. Quantifying the impact of different approaches for handling continuous predictors on the performance of a prognostic model. Stat Med 2016; 35: 4124-35.CrossRefPubMedPubMedCentral Collins GS, Ogundimu EO, Cook JA, Manach YL, Altman DG. Quantifying the impact of different approaches for handling continuous predictors on the performance of a prognostic model. Stat Med 2016; 35: 4124-35.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Kleinbaum DG, Klein M. Logistic Regression-A Self-Learning Text. 3rd ed. New York, NY: Springer; 2010 .CrossRef Kleinbaum DG, Klein M. Logistic Regression-A Self-Learning Text. 3rd ed. New York, NY: Springer; 2010 .CrossRef
17.
Zurück zum Zitat Karkouti K, Callum J, Wijeysundera DN, et al. Point-of-care hemostatic testing in cardiac surgery: a stepped-wedge clustered randomized controlled trial. Circulation 2016; 134: 1152-62.CrossRefPubMed Karkouti K, Callum J, Wijeysundera DN, et al. Point-of-care hemostatic testing in cardiac surgery: a stepped-wedge clustered randomized controlled trial. Circulation 2016; 134: 1152-62.CrossRefPubMed
18.
Zurück zum Zitat Deppe AC, Weber C, Zimmermann J, et al. Point-of-care thromboelastography/thromboelastometry-based coagulation management in cardiac surgery: a meta-analysis of 8332 patients. J Surg Res 2016; 203: 424-33.CrossRefPubMed Deppe AC, Weber C, Zimmermann J, et al. Point-of-care thromboelastography/thromboelastometry-based coagulation management in cardiac surgery: a meta-analysis of 8332 patients. J Surg Res 2016; 203: 424-33.CrossRefPubMed
19.
Zurück zum Zitat Jahn UR, Van Aken H. Near-patient testing-point-of-care or point of costs and convenience? Br J Anaesth 2003; 90: 425-7.CrossRefPubMed Jahn UR, Van Aken H. Near-patient testing-point-of-care or point of costs and convenience? Br J Anaesth 2003; 90: 425-7.CrossRefPubMed
20.
Zurück zum Zitat Baker L, Birnbaum H, Geppert J, Mishol D, Moyneur E. The relationship between technology availability and health care spending. Health Aff (Millwood) 2003; Suppl Web Exclusives: W3-537-51. Baker L, Birnbaum H, Geppert J, Mishol D, Moyneur E. The relationship between technology availability and health care spending. Health Aff (Millwood) 2003; Suppl Web Exclusives: W3-537-51.
21.
Zurück zum Zitat Kilgore ML, Steindel SJ, Smith JA. Continuous quality improvement for point-of-care testing using background monitoring of duplicate specimens. Arch Pathol Lab Med 1999; 123: 824-8.PubMed Kilgore ML, Steindel SJ, Smith JA. Continuous quality improvement for point-of-care testing using background monitoring of duplicate specimens. Arch Pathol Lab Med 1999; 123: 824-8.PubMed
22.
Zurück zum Zitat Toulon P, Ozier Y, Ankri A, Fleron MH, Leroux G, Samama CM. Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery. A multicenter study. Thromb Haemost 2009; 101: 394-401.PubMed Toulon P, Ozier Y, Ankri A, Fleron MH, Leroux G, Samama CM. Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery. A multicenter study. Thromb Haemost 2009; 101: 394-401.PubMed
23.
Zurück zum Zitat Briggs C, Carter J, Lee SH, et al. ICSH Guideline for worldwide point-of-care testing in haematology with special reference to the complete blood count. Int J Lab Hematol 2008; 30: 105-16.CrossRefPubMed Briggs C, Carter J, Lee SH, et al. ICSH Guideline for worldwide point-of-care testing in haematology with special reference to the complete blood count. Int J Lab Hematol 2008; 30: 105-16.CrossRefPubMed
24.
Zurück zum Zitat Halpern MT, Palmer CS, Simpson KN, et al. The economic and clinical efficiency of point-of-care testing for critically ill patients: a decision-analysis model. Am J Med Qual 1998; 13: 3-12.CrossRefPubMed Halpern MT, Palmer CS, Simpson KN, et al. The economic and clinical efficiency of point-of-care testing for critically ill patients: a decision-analysis model. Am J Med Qual 1998; 13: 3-12.CrossRefPubMed
25.
Zurück zum Zitat Kilgore ML, Steindel SJ, Smith JA. Estimating costs and turnaround times: presenting a user-friendly tool for analyzing costs and performance. Clin Lab Manage Rev 1999; 13: 179-87.PubMed Kilgore ML, Steindel SJ, Smith JA. Estimating costs and turnaround times: presenting a user-friendly tool for analyzing costs and performance. Clin Lab Manage Rev 1999; 13: 179-87.PubMed
26.
Zurück zum Zitat Kendall JM, Bevan G, Clancy MJ. Point of care testing in the accident and emergency department: a cost analysis and exploration of financial incentives to use the technology within the hospital. J Health Serv Res Policy 1999; 4: 33-8.CrossRefPubMed Kendall JM, Bevan G, Clancy MJ. Point of care testing in the accident and emergency department: a cost analysis and exploration of financial incentives to use the technology within the hospital. J Health Serv Res Policy 1999; 4: 33-8.CrossRefPubMed
27.
Zurück zum Zitat Wax DB, Reich DL. Changes in utilization of intraoperative laboratory testing associated with the introduction of point-of-care testing devices in an academic department. Anesth Analg 2007; 105: 1711-3.CrossRefPubMed Wax DB, Reich DL. Changes in utilization of intraoperative laboratory testing associated with the introduction of point-of-care testing devices in an academic department. Anesth Analg 2007; 105: 1711-3.CrossRefPubMed
28.
Zurück zum Zitat Chen CL, Lin GA, Bardach NS, et al. Preoperative medical testing in Medicare patients undergoing cataract surgery. N Engl J Med 2015; 372: 1530-8.CrossRefPubMed Chen CL, Lin GA, Bardach NS, et al. Preoperative medical testing in Medicare patients undergoing cataract surgery. N Engl J Med 2015; 372: 1530-8.CrossRefPubMed
Metadaten
Titel
Predictors of intraoperative testing in adults undergoing noncardiac surgery within a regional hospital system
verfasst von
Jessica Spence, MD
Michael Troncone, MD
Steven Long, BSc
Velina Tzankova, MD
Susan Tran, MD
Joshua Peachey, MD
Yannick LeManach, MD, PhD
James Paul, MSc, MD, FRCPC
Publikationsdatum
01.06.2017
Verlag
Springer US
Erschienen in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Ausgabe 6/2017
Print ISSN: 0832-610X
Elektronische ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-017-0857-5

Weitere Artikel der Ausgabe 6/2017

Canadian Journal of Anesthesia/Journal canadien d'anesthésie 6/2017 Zur Ausgabe

Book and New Media Reviews

Manual of ICU Procedures

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

Delir bei kritisch Kranken – Antipsychotika versus Placebo

16.05.2024 Delir Nachrichten

Um die Langzeitfolgen eines Delirs bei kritisch Kranken zu mildern, wird vielerorts auf eine Akuttherapie mit Antipsychotika gesetzt. Eine US-amerikanische Forschungsgruppe äußert jetzt erhebliche Vorbehalte gegen dieses Vorgehen. Denn es gibt neue Daten zum Langzeiteffekt von Haloperidol bzw. Ziprasidon versus Placebo.

Eingreifen von Umstehenden rettet vor Erstickungstod

15.05.2024 Fremdkörperaspiration Nachrichten

Wer sich an einem Essensrest verschluckt und um Luft ringt, benötigt vor allem rasche Hilfe. Dass Umstehende nur in jedem zweiten Erstickungsnotfall bereit waren, diese zu leisten, ist das ernüchternde Ergebnis einer Beobachtungsstudie aus Japan. Doch es gibt auch eine gute Nachricht.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.