Erschienen in:
01.03.2013 | Editorials
Sex-related differences in acute and chronic pain: a bench to bedside perspective
verfasst von:
Katherine A. Mifflin, BSc, Bradley J. Kerr, PhD
Erschienen in:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie
|
Ausgabe 3/2013
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Excerpt
Chronic pain affects the daily lives of millions. It has been estimated that nearly one-quarter of the world’s population suffers from chronic pain, making it the most common human health problem.
1 The most recent estimates of the prevalence of chronic pain in Canada indicate that approximately 29% of the population experiences chronic pain, with nearly 80% of these people reporting their pain as moderate to severe.
2 Interestingly, there is increased pain sensitivity and a higher prevalence of chronic pain conditions in females than in males.
3,
4 To date, however, there has been little basic research examining these sex differences from a mechanistic standpoint, with researchers either doubting or simply ignoring the evidence. Nevertheless, numerous studies and a recent review of the literature provide convincing evidence that there are indeed sex differences relating to chronic and acute pain.
4 …
