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Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging 3/2024

13.11.2023 | Editorial

[18F]FET PET/MR and machine learning in the evaluation of glioma

verfasst von: Leandra Piscopo, Emilia Zampella, Michele Klain

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 3/2024

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Excerpt

Gliomas are the most frequent malignant tumors of the central nervous system (CNS), with an incidence of six cases per 100,000 people every year [1]. Generally, the low-grade gliomas are more frequent in younger patients, while high-grade malignant lesions may occur later [13]. The gold standard of treatment in patients with gliomas consists of surgical resection followed by stereotactic radiotherapy [14]. However, recent advances in genetic engineering led to the identification of transduction pathways implicated in tumor proliferation and differentiation [14]. Therefore, targeted molecular therapies have been introduced as promising therapeutic options in patients with glioma [5, 6]. According to WHO classification, both histology and immunohistochemistry are well-established approaches to tumor characterization [1]. However, the 2021 WHO classification introduced several changes in the classification of CNS tumors, focusing on the role of molecular diagnostics [1]. …
Literatur
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Zurück zum Zitat Law I, Albert NL, Arbizu J, Boellaard R, Drzezga A, Galldiks N,et al. Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0. Eur J Nucl Med Mol Imaging. 2019;46(3):540–557. https://doi.org/10.1007/s00259-018-4207-9. Law I, Albert NL, Arbizu J, Boellaard R, Drzezga A, Galldiks N,et al. Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0. Eur J Nucl Med Mol Imaging. 2019;46(3):540–557. https://​doi.​org/​10.​1007/​s00259-018-4207-9.
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Metadaten
Titel
[18F]FET PET/MR and machine learning in the evaluation of glioma
verfasst von
Leandra Piscopo
Emilia Zampella
Michele Klain
Publikationsdatum
13.11.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 3/2024
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-023-06505-9

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