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Erschienen in: Current Oncology Reports 7/2016

01.07.2016 | Integrative Care (C Lammersfeld, Section Editor)

A Novel Approach to the Nutrigenetics and Nutrigenomics of Obesity and Weight Management

verfasst von: Yael T. Joffe, Christine A. Houghton

Erschienen in: Current Oncology Reports | Ausgabe 7/2016

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Abstract

Nutrigenetics and nutrigenomics, as well as diet and exercise, play an important role in the development and treatment of obesity and its comorbidities. If an individual’s susceptibility to becoming obese and their responsiveness to weight loss interventions are to be understood, then it needs to be addressed at a molecular and metabolic level, including genetic interaction. This review proposes a three-pillar approach to more fully comprehend the complexity of diet-gene interactions in obesity. Peroxisomal proliferating-activated receptor gamma (PPARG) and mitochondrial uncoupling protein-1 (UCP-1) are explored in detail. Illustrating how an understanding of nutritional biochemistry, nutrigenomics, and nutrigenetics may be the key to understanding differences observed in the obese phenotype that vary both within and across populations.
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Metadaten
Titel
A Novel Approach to the Nutrigenetics and Nutrigenomics of Obesity and Weight Management
verfasst von
Yael T. Joffe
Christine A. Houghton
Publikationsdatum
01.07.2016
Verlag
Springer US
Erschienen in
Current Oncology Reports / Ausgabe 7/2016
Print ISSN: 1523-3790
Elektronische ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-016-0529-6

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