What is known:
• Low-level laser therapy (LLLT) was recommended by Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology; however, evidences about LLLT on oral mucositis in pediatric and young patients were insufficient and lack supportive synthesized data.
• Recently, there have been several new RCTs or CCTs for pediatric patients or young adults.
What is new:
• Prophylactic LLLT reduces the occurrence of mucositis and severe mucositis and decreases the average severity of oral mucositis in pediatric and young patients.
• Therapeutic LLLT reduces the average severity of oral mucositis and oral pain.