nach oben

Supportive Care in Cancer

Erschienen in:

06.08.2016 | Original Article

Acupuncture for treating hot flashes in breast cancer patients: an updated meta-analysis

verfasst von: Alireza Salehi, Maryam Marzban, Abbas Rezian Zadeh

Erschienen in: Supportive Care in Cancer | Ausgabe 12/2016

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The aim of this study was to evaluate the effectiveness of acupuncture for treatment of hot flash in women with breast cancer.

Methods

The aspects considered in this study included searching for 12 data bases until April 2015 and consulting reference lists of reviews and related articles. Additional features studied comprised all articles on human patients with breast cancer treated with needle acupuncture with or without electrical stimulation for the treatment of hot flashes. The methodological quality was assessed using the modified Jadad score.

Result

The searches identified 12 relevant articles for inclusion. The meta-analysis without any subgroup or moderator failed to show favorable effects of acupuncture on reducing the frequency of hot flashes after intervention (n = 680, SMD = − 0.478, 95 % CI −0.397 to 0.241, P = 0.632) but exhibited marked heterogeneity of the results (Q value = 83.200, P = 0.000, I^2 = 83.17, τ^2 = 0.310).

Conclusion

The meta-analysis used had contradictory results and yielded no convincing evidence to suggest that acupuncture was an effective treatment of hot flash in patients with breast cancer. Multi-central studies including large sample size are required to investigate the efficiency of acupuncture for treating hot flash in patients with breast cancer.

Rada G, Capurro D, Pantoja T, Corbalán J, Moreno G, Letelier LM, et al (2010) Non-hormonal interventions for hot flushes in women with a history of breast cancer. The Cochrane Library

Bachmann GA (1999) Vasomotor flushes in menopausal women. Am J Obstet Gynecol 999 180:312–3S6CrossRef

Antoine C, Vandromme J, Fastrez M, Carly B, Liebens F, Rozenberg S (2008) A survey among breast cancer survivors: treatment of the climacteric after breast cancer. Climacteric 11:322–328CrossRefPubMed

Pandya KJ, Raubertas RF, Flynn PJ, Hynes HE, Rosenbluth RJ, Kirshner JJ, Pierce HI, Dragalin V, Gary R (2000) Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. Ann Intern Med 132:788–793CrossRefPubMed

Daley A, MacArthur C, McManus R, Stokes-Lampard H, Wilson S, Roalfe A (2006) Factors associated with the use of complementary medicine and non-pharmacological interventions in symptomatic menopausal women. Climacteric 9:336–346CrossRefPubMed

Kessel B, Kronenberg F (2004) The role of complementary and alternative medicine in management of menopausal symptoms. Endocrinol Metab Clin N Am 33:717–739CrossRef

Kronenberg F, Fugh-Berman A (2002) Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med 137:805–813CrossRefPubMed

Newton KM, Buist DS, Keenan NL, Anderson LA, LaCroix AZ (2002) Use of alternative therapies for menopause symptoms: results of a population-based survey. Obstet Gynecol 100:18–25PubMed

Lee MS, Kim K-H, Choi S-M, Ernst E (2009) Acupuncture for treating hot flashes in breast cancer patients: a systematic review. Breast Cancer Res Treat 115:497–503CrossRefPubMed

10.

Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17:1–12CrossRefPubMed

11.

White A, Ernst E (1999) A systematic review of randomized controlled trials of acupuncture for neck pain. Rheumatology 38:143–147CrossRefPubMed

12.

Bao T, Cai L, Snyder C, Betts K, Tarpinian K, Gould J, et al. (2014) Patient-reported outcomes in women with breast cancer enrolled in a dual-center, double-blind, randomized controlled trial assessing the effect of acupuncture in reducing aromatase inhibitor-induced musculoskeletal symptoms. Cancer 120:381–389CrossRefPubMed

13.

Zaborowska E, Brynhildsen J, Damberg S, Fredriksson M, Lindh-Åstrand L, Nedstrand E, et al. (2007) Effects of acupuncture, applied relaxation, estrogens and placebo on hot flushes in postmenopausal women: an analysis of two prospective, parallel, randomized studies. Climacteric 10:38–45CrossRefPubMed

14.

Frisk J, Källström A-C, Wall N, Fredrikson M, Hammar M (2012) Acupuncture improves health-related quality-of-life (HRQoL) and sleep in women with breast cancer and hot flushes. Support Care Cancer 20:715–724CrossRefPubMed

15.

Frisk J, Carlhäll S, Källström A-C, Lindh-Åstrand L, Malmström A, Hammar M (2008) Long-term follow-up of acupuncture and hormone therapy on hot flushes in women with breast cancer: a prospective, randomized, controlled multicenter trial. Climacteric 11:166–174CrossRefPubMed

16.

Hozo SP, Djulbegovic B, Hozo I (2005) Estimating the mean and variance from the median, range, and the size of a sample. BMC 5:13CrossRef

17.

Nedstrand E, Wyon Y, Hammar M, Wijma K (2006) Psychological well-being improves in women with breast cancer after treatment with applied relaxation or electro-acupuncturefor vasomotor symptom. J Psychosom Obstet Gynaecol 27:193–199CrossRefPubMed

18.

Liljegren A, Gunnarsson P, Landgren B-M, Robéus N, Johansson H, Rotstein S (2012) Reducing vasomotor symptoms with acupuncture in breast cancer patients treated with adjuvant tamoxifen: a randomized controlled trial. Breast Cancer Res Treat 135:791–798CrossRefPubMed

19.

Deng G, Vickers AJ, Yeung KS, D'Andrea GM, Xiao H, Heerdt AS, et al. (2007) Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. J Clin Oncol 25:5584–5590CrossRefPubMed

20.

Walker EM, Rodriguez AI, Kohn B, Ball RM, Pegg J, Pocock JR, et al. (2010) Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor–positive breast cancer: a randomized controlled trial. J Clin Oncol 28:634–640CrossRefPubMed

21.

Otte JL, Carpenter JS, Zhong X, Johnstone PA (2011) Feasibility study of acupuncture for reducing sleep disturbances and hot flashes in post-menopausal breast cancer survivors. CNS 25:228PubMedPubMedCentral

22.

de Valois BA, Young TE, Robinson N, McCourt C, Maher EJ (2010) Using traditional acupuncture for breast cancer-related hot flashes and night sweats. J Altern Complement Med 16:1047–1057CrossRefPubMed

23.

Tukmachi E (2000) Treatment of hot flushes in breast cancer patients with acupuncture. Acupunct Med 18:22–27CrossRef

24.

Hervik J, Mjåland O (2009) Acupuncture for the treatment of hot flashes in breast cancer patients, a randomized, controlled trial. Breast Cancer Res Treat 116:311–316CrossRefPubMed

25.

Jeong YJ, Park YS, Kwon HJ, Shin IH, Bong JG, Park SH (2013) Acupuncture for the treatment of hot flashes in patients with breast cancer receiving antiestrogen therapy: a pilot study in Korean women. J Altern Complement Med 19:690–696CrossRefPubMedPubMedCentral

26.

Bokmand S, Flyger H (2013) Acupuncture relieves menopausal discomfort in breast cancer patients: a prospective, double blinded, randomized study. Breast 22:320–323CrossRefPubMed

Titel: Acupuncture for treating hot flashes in breast cancer patients: an updated meta-analysis
verfasst von: Alireza Salehi
Maryam Marzban
Abbas Rezian Zadeh
Publikationsdatum: 06.08.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 12/2016
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-016-3345-5

Springer Medizin

Acupuncture for treating hot flashes in breast cancer patients: an updated meta-analysis

Abstract

Purpose

Methods

Result

Conclusion

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie

Springer Medizin

Abstract

Purpose

Methods

Result

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 12/2016

Cancer experiences and health-related quality of life among racial and ethnic minority survivors of young adult cancer: a mixed methods study

Cost savings of home bortezomib injection in patients with multiple myeloma treated by a combination care in Outpatient Hospital and Hospital care at Home

Outcome and late effects among acute myeloid leukemia survivors: a nationwide population-based study

Multidrug infusions in a Swiss palliative care unit: assessment of frequent combinations in terms of clinical effectiveness, compatibility, and stability

“Melanoma: Questions and Answers.” Development and evaluation of a psycho-educational resource for people with a history of melanoma

Examining racial variation in antiemetic use and post-chemotherapy health care utilization for nausea and vomiting among breast cancer patients

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie