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Erschienen in:
29.03.2021 | Clinical Image
Acute Allergic Contact Dermatitis Presenting with Tense Bullous Eruption
Erschienen in: Journal of General Internal Medicine | Ausgabe 7/2021
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A 29-year-old man presented with a 7-day history of a pruritic bullous eruption following outdoor exposure. He denied using new skin products or topical or oral medications. Physical examination revealed lower extremity bullae over erythematous patches with negative Nikolsky sign (Fig. 1a). Skin biopsy diagnosed allergic contact dermatitis (ACD) (Fig. 1b).
Figure 1
a Lower extremity vesicles and tense bullae overlying a diffuse erythematous patch. b Histological sections (×10) demonstrate spongiosis of the epidermis (gray arrow) with exocytosis of lymphocytes with a perivascular lymphocytic infiltrate with scattered eosinophils (black arrows), consistent with ACD. Direct immunofluorescence testing (not imaged here) was negative for IgA, IgG, IgM, and C3.
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