Erschienen in:
01.07.2009 | Case report
Acute chest pain in a patient treated with capecitabine
verfasst von:
C. Camaro, P. W. Danse, H. A. Bosker
Erschienen in:
Netherlands Heart Journal
|
Ausgabe 7/2009
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Abstract
A 61-year-old male with a history of metastatic colorectal cancer was referred to our hospital for primary coronary intervention because of acute ST-elevation myocardial infarction. Coronary angiography, however, revealed no significant stenoses. When asked, the patient revealed that capecitabine (Xeloda®) was started by his oncologist one day before admission. It is known that this oral 5-FU analogue drug, used in metastatic colorectal cancer, can cause coronary artery spasms. The main treatment of capecitabine-induced vasospasm is discontinuation of the drug. Indeed, after cessation of the drug the patient remained free of symptoms and the ECG abnormalities normalised. (Neth Heart J 2009;17:288–91.)