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Erschienen in: Archives of Orthopaedic and Trauma Surgery 9/2010

01.09.2010 | Osteoporotic Fracture Management

Adjacent vertebral fractures after percutaneous vertebral augmentation of osteoporotic vertebral compression fracture: a comparison of balloon kyphoplasty and vertebroplasty

verfasst von: I. Movrin, R. Vengust, R. Komadina

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 9/2010

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Abstract

Introduction

It is still controversial whether adjacent level compression fractures after balloon kyphoplasty (BK) and vertebroplasty (VP) should be regarded as the consequence of stiffness achieved by augmentation with bone cement or if the adjacent level fractures are simply the result of the natural progression of osteoporosis. The purpose of this study was to evaluate the adjacent level fracture risk after BK as compared with VP and to determine the possible dominant risk factor associated with new compression fractures.

Materials and methods

73 consecutive patients with painful vertebral compression fractures (VCFs) were enrolled in a prospective nonrandomized study. BK was performed in 46 patients (51 vertebral bodies) and VP in 27 patients (32 vertebral bodies). The first patient’s visit was before the operative procedure, when clinical and radiographical examinations were done. The follow-up visits, considered in the analysis, were on the first day and after 1 year, postoperatively.

Results

In 1 year, 3 out of 46 patients (6.5%) treated with BK, and 2 out of 27 patients (7.4%) treated with VP sustained adjacent level fracture. More patients with a BMD higher or equal to 3.0 experienced a new fracture than those with a BMD less than 3.0 (odds ratio = 13.00; 95% confidence interval: 1.35–124.81), and the risk for adjacent level fractures decreased significantly when the postoperative kyphotic angle was less than 9° compared with that of higher or equal to 9° (odds ratio = 12.00; 95% confidence interval: 1.25–114.88).

Conclusion

Our results indicate that BK and VP are methods with a low risk of adjacent level fractures. The most important factors for new VCFs after a percutaneous augmentation procedure are the degree of osteoporosis and altered biomechanics in the treated area of the spine due to resistant kyphosis. These results suggest that the adjacent vertebrae would fracture eventually, even without the procedure. BK and VP offer a comparable rate of pain relief.
Literatur
1.
Zurück zum Zitat Aebli N et al (2002) Fat embolism and acute hypotension during vertebroplasty: an experimental study in sheep. Spine (Phila Pa 1976) 27(5):460–466 Aebli N et al (2002) Fat embolism and acute hypotension during vertebroplasty: an experimental study in sheep. Spine (Phila Pa 1976) 27(5):460–466
2.
Zurück zum Zitat Ananthakrishnan D et al (2005) The effect on anterior column loading due to different vertebral augmentation techniques. Clin Biomech (Bristol, Avon) 20(1):25–31CrossRef Ananthakrishnan D et al (2005) The effect on anterior column loading due to different vertebral augmentation techniques. Clin Biomech (Bristol, Avon) 20(1):25–31CrossRef
3.
Zurück zum Zitat Assessment of fracture risk, its application to screening for postmenopausal osteoporosis (1994) Report of a WHO Study Group. World Health Organ Tech Rep Ser 843:1–129 Assessment of fracture risk, its application to screening for postmenopausal osteoporosis (1994) Report of a WHO Study Group. World Health Organ Tech Rep Ser 843:1–129
4.
Zurück zum Zitat Barr JD et al (2000) Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine (Phila Pa 1976) 25(8):923–928 Barr JD et al (2000) Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine (Phila Pa 1976) 25(8):923–928
5.
Zurück zum Zitat Belkoff SM et al (2001) An ex vivo biomechanical evaluation of an inflatable bone tamp used in the treatment of compression fracture. Spine (Phila Pa 1976) 26(2):151–156 Belkoff SM et al (2001) An ex vivo biomechanical evaluation of an inflatable bone tamp used in the treatment of compression fracture. Spine (Phila Pa 1976) 26(2):151–156
6.
Zurück zum Zitat Berlemann U et al (2002) Adjacent vertebral failure after vertebroplasty. A biomechanical investigation. J Bone Joint Surg Br 84(5):748–752CrossRefPubMed Berlemann U et al (2002) Adjacent vertebral failure after vertebroplasty. A biomechanical investigation. J Bone Joint Surg Br 84(5):748–752CrossRefPubMed
7.
Zurück zum Zitat Briggs AM et al (2006) The effect of osteoporotic vertebral fracture on predicted spinal loads in vivo. Eur Spine J 15(12):1785–1795CrossRefPubMed Briggs AM et al (2006) The effect of osteoporotic vertebral fracture on predicted spinal loads in vivo. Eur Spine J 15(12):1785–1795CrossRefPubMed
8.
Zurück zum Zitat Cook DJ et al (1993) Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 36(6):750–756CrossRefPubMed Cook DJ et al (1993) Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum 36(6):750–756CrossRefPubMed
9.
Zurück zum Zitat Deramond H et al (1997) Percutaneous vertebroplasty. Semin Musculoskelet Radiol 1(2):285–296CrossRefPubMed Deramond H et al (1997) Percutaneous vertebroplasty. Semin Musculoskelet Radiol 1(2):285–296CrossRefPubMed
10.
Zurück zum Zitat Diamond TH, Champion B, Clark WA (2003) Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. Am J Med 114(4):257–265CrossRefPubMed Diamond TH, Champion B, Clark WA (2003) Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. Am J Med 114(4):257–265CrossRefPubMed
11.
Zurück zum Zitat Fribourg D et al (2004) Incidence of subsequent vertebral fracture after kyphoplasty. Spine (Phila Pa 1976) 29(20):2270–2276 (discussion 2277) Fribourg D et al (2004) Incidence of subsequent vertebral fracture after kyphoplasty. Spine (Phila Pa 1976) 29(20):2270–2276 (discussion 2277)
12.
Zurück zum Zitat Galibert P et al (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 33(2):166–168PubMed Galibert P et al (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 33(2):166–168PubMed
13.
Zurück zum Zitat Garfin SR, Yuan HA, Reiley MA (2001) New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine (Phila Pa 1976) 26(14):1511–1515 Garfin SR, Yuan HA, Reiley MA (2001) New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine (Phila Pa 1976) 26(14):1511–1515
14.
Zurück zum Zitat Genant HK et al (1999) Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int 10(4):259–264CrossRefPubMed Genant HK et al (1999) Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int 10(4):259–264CrossRefPubMed
15.
Zurück zum Zitat Grados F et al (2000) Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford) 39(12):1410–1414CrossRef Grados F et al (2000) Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford) 39(12):1410–1414CrossRef
16.
Zurück zum Zitat Greene DL et al (2007) The eggshell technique for prevention of cement leakage during kyphoplasty. J Spinal Disord Tech 20(3):229–232CrossRefPubMed Greene DL et al (2007) The eggshell technique for prevention of cement leakage during kyphoplasty. J Spinal Disord Tech 20(3):229–232CrossRefPubMed
17.
Zurück zum Zitat Felsenberg D et al (2002) Incidence of vertebral fracture in europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 17(4):716–724CrossRef Felsenberg D et al (2002) Incidence of vertebral fracture in europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 17(4):716–724CrossRef
18.
Zurück zum Zitat Hiwatashi A et al (2003) Increase in vertebral body height after vertebroplasty. AJNR Am J Neuroradiol 24(2):185–189PubMed Hiwatashi A et al (2003) Increase in vertebral body height after vertebroplasty. AJNR Am J Neuroradiol 24(2):185–189PubMed
19.
Zurück zum Zitat Hulme PA et al (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine (Phila Pa 1976) 31(17):1983–2001 Hulme PA et al (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine (Phila Pa 1976) 31(17):1983–2001
20.
Zurück zum Zitat Kim MJ et al (2006) Vertebroplasty versus kyphoplasty: biomechanical behavior under repetitive loading conditions. Spine (Phila Pa 1976) 31(18):2079–2084 Kim MJ et al (2006) Vertebroplasty versus kyphoplasty: biomechanical behavior under repetitive loading conditions. Spine (Phila Pa 1976) 31(18):2079–2084
21.
Zurück zum Zitat Kim SH et al (2004) Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol 45(4):440–445CrossRefPubMed Kim SH et al (2004) Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol 45(4):440–445CrossRefPubMed
22.
Zurück zum Zitat Klotzbuecher CM et al (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15(4):721–739CrossRefPubMed Klotzbuecher CM et al (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15(4):721–739CrossRefPubMed
23.
Zurück zum Zitat Komemushi A et al (2006) Percutaneous vertebroplasty for osteoporotic compression fracture: multivariate study of predictors of new vertebral body fracture. Cardiovasc Intervent Radiol 29(4):580–585CrossRefPubMed Komemushi A et al (2006) Percutaneous vertebroplasty for osteoporotic compression fracture: multivariate study of predictors of new vertebral body fracture. Cardiovasc Intervent Radiol 29(4):580–585CrossRefPubMed
24.
Zurück zum Zitat Kuklo TR et al (2001) Measurement of thoracic and lumbar fracture kyphosis: evaluation of intraobserver, interobserver, and technique variability. Spine (Phila Pa 1976) 26(1):61–65 (discussion 66) Kuklo TR et al (2001) Measurement of thoracic and lumbar fracture kyphosis: evaluation of intraobserver, interobserver, and technique variability. Spine (Phila Pa 1976) 26(1):61–65 (discussion 66)
25.
Zurück zum Zitat Leib ES et al (2004) Official positions of the International Society for Clinical Densitometry. J Clin Densitom 7(1):1–6CrossRefPubMed Leib ES et al (2004) Official positions of the International Society for Clinical Densitometry. J Clin Densitom 7(1):1–6CrossRefPubMed
26.
Zurück zum Zitat Liebschner MA, Rosenberg WS, Keaveny TM (2001) Effects of bone cement volume and distribution on vertebral stiffness after vertebroplasty. Spine 26(14):1547–1554CrossRefPubMed Liebschner MA, Rosenberg WS, Keaveny TM (2001) Effects of bone cement volume and distribution on vertebral stiffness after vertebroplasty. Spine 26(14):1547–1554CrossRefPubMed
27.
Zurück zum Zitat Lin EP et al (2004) Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol 25(2):175–180PubMed Lin EP et al (2004) Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol 25(2):175–180PubMed
28.
Zurück zum Zitat Lindsay R, Burge RT, Strauss DM (2005) One year outcomes and costs following a vertebral fracture. Osteoporos Int 16(1):78–85CrossRefPubMed Lindsay R, Burge RT, Strauss DM (2005) One year outcomes and costs following a vertebral fracture. Osteoporos Int 16(1):78–85CrossRefPubMed
29.
Zurück zum Zitat Lindsay R et al (2001) Risk of new vertebral fracture in the year following a fracture. JAMA 285(3):320–323CrossRefPubMed Lindsay R et al (2001) Risk of new vertebral fracture in the year following a fracture. JAMA 285(3):320–323CrossRefPubMed
30.
Zurück zum Zitat Lunt M et al (2003) Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS). Bone 33(4):505–513CrossRefPubMed Lunt M et al (2003) Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS). Bone 33(4):505–513CrossRefPubMed
31.
Zurück zum Zitat McKiernan F, Jensen R, Faciszewski T (2003) The dynamic mobility of vertebral compression fractures. J Bone Miner Res 18(1):24–29CrossRefPubMed McKiernan F, Jensen R, Faciszewski T (2003) The dynamic mobility of vertebral compression fractures. J Bone Miner Res 18(1):24–29CrossRefPubMed
32.
Zurück zum Zitat Melton LJ 3rd et al (1999) Vertebral fractures predict subsequent fractures. Osteoporos Int 10(3):214–221CrossRefPubMed Melton LJ 3rd et al (1999) Vertebral fractures predict subsequent fractures. Osteoporos Int 10(3):214–221CrossRefPubMed
33.
Zurück zum Zitat Perez-Higueras A et al (2002) Percutaneous vertebroplasty: long-term clinical and radiological outcome. Neuroradiology 44(11):950–954CrossRefPubMed Perez-Higueras A et al (2002) Percutaneous vertebroplasty: long-term clinical and radiological outcome. Neuroradiology 44(11):950–954CrossRefPubMed
34.
Zurück zum Zitat Phillips FM et al (2002) An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty. Spine (Phila Pa 1976) 27(19):2173–2178 (discussion 2178–2179) Phillips FM et al (2002) An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty. Spine (Phila Pa 1976) 27(19):2173–2178 (discussion 2178–2179)
35.
Zurück zum Zitat Polikeit A, Nolte LP, Ferguson SJ (2003) The effect of cement augmentation on the load transfer in an osteoporotic functional spinal unit: finite-element analysis. Spine (Phila Pa 1976) 28(10):991–996 Polikeit A, Nolte LP, Ferguson SJ (2003) The effect of cement augmentation on the load transfer in an osteoporotic functional spinal unit: finite-element analysis. Spine (Phila Pa 1976) 28(10):991–996
36.
Zurück zum Zitat Takata S, Yasui N (2001) Disuse osteoporosis. J Med Invest 48(3–4):147–156PubMed Takata S, Yasui N (2001) Disuse osteoporosis. J Med Invest 48(3–4):147–156PubMed
37.
Zurück zum Zitat Taylor RS, Taylor RJ, Fritzell P (2006) Balloon kyphoplasty and vertebroplasty for vertebral compression fractures: a comparative systematic review of efficacy and safety. Spine (Phila Pa 1976) 31(23):2747–2755 Taylor RS, Taylor RJ, Fritzell P (2006) Balloon kyphoplasty and vertebroplasty for vertebral compression fractures: a comparative systematic review of efficacy and safety. Spine (Phila Pa 1976) 31(23):2747–2755
38.
Zurück zum Zitat Teng MM et al (2003) Kyphosis correction and height restoration effects of percutaneous vertebroplasty. AJNR Am J Neuroradiol 24(9):1893–1900PubMed Teng MM et al (2003) Kyphosis correction and height restoration effects of percutaneous vertebroplasty. AJNR Am J Neuroradiol 24(9):1893–1900PubMed
39.
Zurück zum Zitat Uppin AA et al (2003) Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology 226(1):119–124CrossRefPubMed Uppin AA et al (2003) Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology 226(1):119–124CrossRefPubMed
40.
Zurück zum Zitat Villarraga ML et al (2005) The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies. J Spinal Disord Tech 18(1):84–91CrossRefPubMed Villarraga ML et al (2005) The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies. J Spinal Disord Tech 18(1):84–91CrossRefPubMed
41.
Zurück zum Zitat Vittinghoff E, McCulloch CE (2007) Relaxing the rule of ten events per variable in logistic and Cox regression. Am J Epidemiol 165(6):710–718CrossRefPubMed Vittinghoff E, McCulloch CE (2007) Relaxing the rule of ten events per variable in logistic and Cox regression. Am J Epidemiol 165(6):710–718CrossRefPubMed
42.
Zurück zum Zitat Yeom JS et al (2003) Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fractures. J Bone Joint Surg Br 85(1):83–89 Yeom JS et al (2003) Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fractures. J Bone Joint Surg Br 85(1):83–89
Metadaten
Titel
Adjacent vertebral fractures after percutaneous vertebral augmentation of osteoporotic vertebral compression fracture: a comparison of balloon kyphoplasty and vertebroplasty
verfasst von
I. Movrin
R. Vengust
R. Komadina
Publikationsdatum
01.09.2010
Verlag
Springer-Verlag
Erschienen in
Archives of Orthopaedic and Trauma Surgery / Ausgabe 9/2010
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-010-1106-3

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