Erschienen in:
01.05.2005 | Oral presentation
Adjuvant chemotherapy for operable breast cancer: old vs new schema
verfasst von:
P Valagussa, L Gianni, G Bonadonna
Erschienen in:
Breast Cancer Research
|
Sonderheft 1/2005
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Excerpt
In 1975 we presented our first report on the efficacy of cyclophosphamide, methotrexate and fluorouracil (CMF) as adjuvant treatment for node-positive breast cancer. Thirty years later, the results of this study demonstrate that the significant advantage in both relapse-free (reduction in relative risk for relapse of 29%) and overall survival (reduction in relative risk for death of 21%) persists over the years and that adjuvant CMF can exert a moderate but worthwhile suppression of micrometastases, regardless of anatomical sites [
1]. …