Skip to main content
Erschienen in: European Journal of Orthopaedic Surgery & Traumatology 1/2019

17.08.2018 | Original Article • KNEE - OSTEOTOMY

Advantages of creation of holes and removal of air in artificial bone for early bone formation when used artificial bone as a gap filler in open wedge high tibial osteotomy

verfasst von: Yasuaki Tohma, Ryohei Takeuchi, Yasuhito Tanaka

Erschienen in: European Journal of Orthopaedic Surgery & Traumatology | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

Recently, many facilities perform open wedge high tibial osteotomy (OWHTO) using artificial bone as a gap filler. However, there are many cases in which artificial bone is used without a clear purpose. We recommend a surgical technique to promote early synostosis between artificial bone and recipient bone due to mechanical support especially in the early stage after OWHTO. At our hospital, beta-tricalcium phosphate (β-TCP) with 60% porosity is used in OWHTO. Initially, a wedge-shaped block-type β-TCP, as large as possible, was inserted into the gap. However, from the standpoint of initial mechanical support, we changed the artificial bone size and created intentional holes. Furthermore, we removed air bubbles from β-TCP. We evaluated the synostosis on the basis of clinical results and diagnostic imaging. As a result of creating holes and removing air from the artificial bone, a trend toward faster synostosis was noted, especially at the early stage. No adverse events such as tibial plateau fracture, lateral cortical fracture, plate and screw failure and correction loss due to reducing the size of the artificial bone occurred, but placement of the artificial bone in contact with cortical bone and surface contact installation with the recipient bone tissue was important. When using artificial bone in OWHTO, holes formation and removal of air from the artificial bone are recommended for faster synostosis between artificial bone and recipient bone in the early stage after surgery. Artificial bone should be used, with attention to its positioning and shape, for efficient mechanical support.
Literatur
1.
Zurück zum Zitat Lobenhoffer P, Agneskirchner JD (2003) Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 11:132–138CrossRefPubMed Lobenhoffer P, Agneskirchner JD (2003) Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 11:132–138CrossRefPubMed
2.
Zurück zum Zitat Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia–early results in 92 cases. Injury 34(Suppl 2):B55–B62CrossRefPubMed Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia–early results in 92 cases. Injury 34(Suppl 2):B55–B62CrossRefPubMed
3.
Zurück zum Zitat Takeuchi R, Ishikawa H, Aratake M, Bito H, Saito I, Kumagai K, Akamatsu Y, Saito T (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53CrossRefPubMed Takeuchi R, Ishikawa H, Aratake M, Bito H, Saito I, Kumagai K, Akamatsu Y, Saito T (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53CrossRefPubMed
4.
Zurück zum Zitat Onodera J, Kondo E, Omizu N, Ueda D, Yagi T, Yasuda K (2014) Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 22:2763–2770CrossRefPubMed Onodera J, Kondo E, Omizu N, Ueda D, Yagi T, Yasuda K (2014) Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 22:2763–2770CrossRefPubMed
5.
Zurück zum Zitat Takeuchi R, Aratake M, Bito H, Saito I, Kumagai K, Ishikawa H, Akamatsu Y, Sasaki Y, Saito T (2008) Simultaneous bilateral opening-wedge high tibial osteotomy with early full weight bearing exercise. Knee Surg Sports Traumatol Arthrosc 16:1030–1037CrossRefPubMed Takeuchi R, Aratake M, Bito H, Saito I, Kumagai K, Ishikawa H, Akamatsu Y, Sasaki Y, Saito T (2008) Simultaneous bilateral opening-wedge high tibial osteotomy with early full weight bearing exercise. Knee Surg Sports Traumatol Arthrosc 16:1030–1037CrossRefPubMed
6.
Zurück zum Zitat Takeuchi R, Aratake M, Bito H, Saito I, Kumagai K, Hayashi R, Sasaki Y, Akamatsu Y, Ishikawa H, Amakado E, Aota Y, Saito T (2009) Clinical results and radiographical evaluation of opening wedge high tibial osteotomy for spontaneous osteonecrosis of the knee. Knee Surg Sports Traumatol Arthrosc 17:361–368CrossRef Takeuchi R, Aratake M, Bito H, Saito I, Kumagai K, Hayashi R, Sasaki Y, Akamatsu Y, Ishikawa H, Amakado E, Aota Y, Saito T (2009) Clinical results and radiographical evaluation of opening wedge high tibial osteotomy for spontaneous osteonecrosis of the knee. Knee Surg Sports Traumatol Arthrosc 17:361–368CrossRef
7.
Zurück zum Zitat Takeuchi R, Bito H, Akamatsu Y, Shiraishi T, Morishita S, Koshino T, Saito T (2010) In vitro stability of open wedge high tibial osteotomy with synthetic bone graft. Knee 17(3):217–220CrossRefPubMed Takeuchi R, Bito H, Akamatsu Y, Shiraishi T, Morishita S, Koshino T, Saito T (2010) In vitro stability of open wedge high tibial osteotomy with synthetic bone graft. Knee 17(3):217–220CrossRefPubMed
8.
Zurück zum Zitat van Hemert WL, Willems K, Anderson PG, van Heerwaarden RJ, Wymenga AB (2004) Tricalcium phosphate granules or rigid wedge performs in open wedge high tibial osteotomy: a radiological study with a new evaluation system. Knee 11:451–456CrossRefPubMed van Hemert WL, Willems K, Anderson PG, van Heerwaarden RJ, Wymenga AB (2004) Tricalcium phosphate granules or rigid wedge performs in open wedge high tibial osteotomy: a radiological study with a new evaluation system. Knee 11:451–456CrossRefPubMed
9.
Zurück zum Zitat Hernigou P, Roussignol X, Flouzat-Lachaniette CH, Filippini P, Guissou I, Poignard A (2010) Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges. Int Orthop 34:191–199CrossRefPubMed Hernigou P, Roussignol X, Flouzat-Lachaniette CH, Filippini P, Guissou I, Poignard A (2010) Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges. Int Orthop 34:191–199CrossRefPubMed
10.
Zurück zum Zitat TohmaY Ohgushi H, Dohi Y, Shimaoka H, Ikeda Y, MizutaY Takakura Y (2003) Quantitative analysis of bone formation in the composites of cultured marrow cells and hydroxyapatite by X-ray computed tomography. Key Eng Mater 240–242:615–618CrossRef TohmaY Ohgushi H, Dohi Y, Shimaoka H, Ikeda Y, MizutaY Takakura Y (2003) Quantitative analysis of bone formation in the composites of cultured marrow cells and hydroxyapatite by X-ray computed tomography. Key Eng Mater 240–242:615–618CrossRef
11.
Zurück zum Zitat Okamoto M, Dohi Y, Ohgushi H, Shimaoka H, Ikeuchi M, Matsushima A, Yonemasu K, Hosoi H (2006) Influence of the porosity of hydroxyapatite ceramics on in vitro and in vivo bone formation by cultured rat bone marrow stromal cells. J Mater Sci Mater Med 17:327–336CrossRefPubMed Okamoto M, Dohi Y, Ohgushi H, Shimaoka H, Ikeuchi M, Matsushima A, Yonemasu K, Hosoi H (2006) Influence of the porosity of hydroxyapatite ceramics on in vitro and in vivo bone formation by cultured rat bone marrow stromal cells. J Mater Sci Mater Med 17:327–336CrossRefPubMed
12.
Zurück zum Zitat Brosset T, Pasquier G, Migaud H, Gougeon F (2011) Opening wedge high tibial osteotomy performed without filling the defect but with locking plate fixation (TomoFix™) and early weight-bearing: prospective evaluation of bone union, precision and maintenance of correction in 51 cases. Orthop Traumatol Surg Res 97:705–711CrossRefPubMed Brosset T, Pasquier G, Migaud H, Gougeon F (2011) Opening wedge high tibial osteotomy performed without filling the defect but with locking plate fixation (TomoFix™) and early weight-bearing: prospective evaluation of bone union, precision and maintenance of correction in 51 cases. Orthop Traumatol Surg Res 97:705–711CrossRefPubMed
13.
Zurück zum Zitat Dejour H, Bonnin M (1994) Tibial translation after anterior cruciate ligament rupture. Two radiological tests compared. J Bone Joint Surg Br 76:745–749CrossRefPubMed Dejour H, Bonnin M (1994) Tibial translation after anterior cruciate ligament rupture. Two radiological tests compared. J Bone Joint Surg Br 76:745–749CrossRefPubMed
14.
Zurück zum Zitat Yanasse RH, Cavallari CE, Chaud FL, Hernandez AJ, Mizobuchi RR, Laraya MH (2009) Measurement of tibial slope angle after medial opening wedge high tibial osteotomy: case series. Sao Paulo Med J 127:34–39CrossRefPubMed Yanasse RH, Cavallari CE, Chaud FL, Hernandez AJ, Mizobuchi RR, Laraya MH (2009) Measurement of tibial slope angle after medial opening wedge high tibial osteotomy: case series. Sao Paulo Med J 127:34–39CrossRefPubMed
15.
Zurück zum Zitat Altermatt S, Schwöbel M, Pochon JP (1992) Operative treatment of solitary bone cysts with tricalcium phosphate ceramic. A 1 to 7 year follow-up. Eur J Pediatr Surg 2:180–182CrossRefPubMed Altermatt S, Schwöbel M, Pochon JP (1992) Operative treatment of solitary bone cysts with tricalcium phosphate ceramic. A 1 to 7 year follow-up. Eur J Pediatr Surg 2:180–182CrossRefPubMed
16.
Zurück zum Zitat Handschel J, Wiesmann HP, Stratmann U, Kleinheinz J, Meyer U, Joos U (2002) TCP is hardly resorbed and not osteoconductive in a non-loading calvarial model. Biomaterials 23:1689–1695CrossRefPubMed Handschel J, Wiesmann HP, Stratmann U, Kleinheinz J, Meyer U, Joos U (2002) TCP is hardly resorbed and not osteoconductive in a non-loading calvarial model. Biomaterials 23:1689–1695CrossRefPubMed
17.
Zurück zum Zitat Neo M, Herbst H, Voigt CF, Gross UM (1998) Temporal and spatial patterns of osteoblast activation following implantation of beta-TCP particles into bone. J Biomed Mater Res 39:71–76CrossRefPubMed Neo M, Herbst H, Voigt CF, Gross UM (1998) Temporal and spatial patterns of osteoblast activation following implantation of beta-TCP particles into bone. J Biomed Mater Res 39:71–76CrossRefPubMed
18.
Zurück zum Zitat Liu G, Zhao L, Zhang W, Cui L, Liu W, Cao Y (2008) Repair of goat tibial defects with bone marrow stromal cells and beta-tricalcium phosphate. J Mater Sci Mater Med 19:2367–2376CrossRefPubMed Liu G, Zhao L, Zhang W, Cui L, Liu W, Cao Y (2008) Repair of goat tibial defects with bone marrow stromal cells and beta-tricalcium phosphate. J Mater Sci Mater Med 19:2367–2376CrossRefPubMed
19.
Zurück zum Zitat Eggli PS, Müller W, Schenk RK (1988) Porous hydroxyapatite and tricalcium phosphate cylinders with two different pore size ranges implanted in the cancellous bone of rabbits. A comparative histomorphometric and histologic study of bony ingrowth and implant substitution. Clin Orthop Relat Res 232:127–138 Eggli PS, Müller W, Schenk RK (1988) Porous hydroxyapatite and tricalcium phosphate cylinders with two different pore size ranges implanted in the cancellous bone of rabbits. A comparative histomorphometric and histologic study of bony ingrowth and implant substitution. Clin Orthop Relat Res 232:127–138
20.
Zurück zum Zitat Murphy CM, Haugh MG, O’Brien FJ (2010) The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 31:461–466CrossRefPubMed Murphy CM, Haugh MG, O’Brien FJ (2010) The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 31:461–466CrossRefPubMed
21.
Zurück zum Zitat Torigoe I, Sotome S, Tsuchiya A, Yoshii T, Takahashi M, Kawabata S, Shinomiya K (2007) Novel cell seeding system into a porous scaffold using a modified low-pressure method to enhance cell seeding efficiency and bone formation. Cell Transpl 16:729–739CrossRef Torigoe I, Sotome S, Tsuchiya A, Yoshii T, Takahashi M, Kawabata S, Shinomiya K (2007) Novel cell seeding system into a porous scaffold using a modified low-pressure method to enhance cell seeding efficiency and bone formation. Cell Transpl 16:729–739CrossRef
22.
Zurück zum Zitat Masaoka T, Yoshii T, Yuasa M, Yamada T, Taniyama T, Torigoe I, Shinomiya K, Okawa A, Morita S, Sotome S (2016) Bone defect regeneration by a combination of a β-tricalcium phosphate scaffold and bone marrow stromal cells in a non-human primate model. Open Biomed Eng J 18(10):2–11CrossRef Masaoka T, Yoshii T, Yuasa M, Yamada T, Taniyama T, Torigoe I, Shinomiya K, Okawa A, Morita S, Sotome S (2016) Bone defect regeneration by a combination of a β-tricalcium phosphate scaffold and bone marrow stromal cells in a non-human primate model. Open Biomed Eng J 18(10):2–11CrossRef
23.
Zurück zum Zitat Yoshii T, Sotome S, Torigoe I, Tsuchiya A, Maehara H, Ichinose S, Shinomiya K (2009) Fresh bone marrow introduction into porous scaffolds using a simple low-pressure loading method for effective osteogenesis in a rabbit model. J Orthop Res 27:1–7CrossRefPubMed Yoshii T, Sotome S, Torigoe I, Tsuchiya A, Maehara H, Ichinose S, Shinomiya K (2009) Fresh bone marrow introduction into porous scaffolds using a simple low-pressure loading method for effective osteogenesis in a rabbit model. J Orthop Res 27:1–7CrossRefPubMed
24.
Zurück zum Zitat Zhou YF, Sae-Lim V, Chou AM, Hutmacher DW, Lim TM (2006) Does seeding density affect in vitro mineral nodules formation in novel composite scaffolds? J Biomed Mater Res A 78:183–193CrossRefPubMed Zhou YF, Sae-Lim V, Chou AM, Hutmacher DW, Lim TM (2006) Does seeding density affect in vitro mineral nodules formation in novel composite scaffolds? J Biomed Mater Res A 78:183–193CrossRefPubMed
25.
Zurück zum Zitat Hasegawa T, Miwa M, Sakai Y, Niikura T, Lee SY, Oe K, Iwakura T, Kurosaka M, Komori T (2010) Efficient cell-seeding into scaffolds improves bone formation. J Dent Res 89:854–859CrossRefPubMed Hasegawa T, Miwa M, Sakai Y, Niikura T, Lee SY, Oe K, Iwakura T, Kurosaka M, Komori T (2010) Efficient cell-seeding into scaffolds improves bone formation. J Dent Res 89:854–859CrossRefPubMed
26.
Zurück zum Zitat Torigoe I, Sotome S, Tsuchiya A, Yoshii T, Maehara H, Sugata Y, Ichinose S, Shinomiya K, Okawa A (2009) Bone regeneration with autologous plasma, bone marrow stromal cells, and porous beta-tricalcium phosphate in nonhuman primates. Tissue Eng Part A 15:1489–1499CrossRefPubMed Torigoe I, Sotome S, Tsuchiya A, Yoshii T, Maehara H, Sugata Y, Ichinose S, Shinomiya K, Okawa A (2009) Bone regeneration with autologous plasma, bone marrow stromal cells, and porous beta-tricalcium phosphate in nonhuman primates. Tissue Eng Part A 15:1489–1499CrossRefPubMed
27.
Zurück zum Zitat Sago T, Mori Y, Takagi H, Iwata H, Murase K, Kawamura Y, Hirose H (2003) Local treatment of Dacron patch graft contaminated with Staphylococcus aureus using antibiotic-releasing porous apatite ceramic: an experimental study in the rabbit. J Vasc Surg 37:169–174CrossRefPubMed Sago T, Mori Y, Takagi H, Iwata H, Murase K, Kawamura Y, Hirose H (2003) Local treatment of Dacron patch graft contaminated with Staphylococcus aureus using antibiotic-releasing porous apatite ceramic: an experimental study in the rabbit. J Vasc Surg 37:169–174CrossRefPubMed
28.
Zurück zum Zitat Itokazu M, Yang W, Aoki T, Ohara A, Kato N (1998) Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testing. Biomaterials 19:817–819CrossRefPubMed Itokazu M, Yang W, Aoki T, Ohara A, Kato N (1998) Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testing. Biomaterials 19:817–819CrossRefPubMed
29.
Zurück zum Zitat Rodner CM, Adams DJ, Diaz-Doran V, Tate JP, Santangelo SA, Mazzocca AD, Arciero RA (2006) Medial opening wedge tibial osteotomy and the sagittal plane: the effect of increasing tibial slope on tibiofemoral contact pressure. Am J Sports Med 34:1431–1441CrossRefPubMed Rodner CM, Adams DJ, Diaz-Doran V, Tate JP, Santangelo SA, Mazzocca AD, Arciero RA (2006) Medial opening wedge tibial osteotomy and the sagittal plane: the effect of increasing tibial slope on tibiofemoral contact pressure. Am J Sports Med 34:1431–1441CrossRefPubMed
30.
Zurück zum Zitat Ogawa H, Matsumoto K, Ogawa T, Takeuchi K, Akiyama H (2016) Effect of wedge insertion angle on posterior tibial slope in medial opening wedge high tibial osteotomy. Orthop J Sports Med 4(2):2325967116630748CrossRefPubMedPubMedCentral Ogawa H, Matsumoto K, Ogawa T, Takeuchi K, Akiyama H (2016) Effect of wedge insertion angle on posterior tibial slope in medial opening wedge high tibial osteotomy. Orthop J Sports Med 4(2):2325967116630748CrossRefPubMedPubMedCentral
Metadaten
Titel
Advantages of creation of holes and removal of air in artificial bone for early bone formation when used artificial bone as a gap filler in open wedge high tibial osteotomy
verfasst von
Yasuaki Tohma
Ryohei Takeuchi
Yasuhito Tanaka
Publikationsdatum
17.08.2018
Verlag
Springer Paris
Erschienen in
European Journal of Orthopaedic Surgery & Traumatology / Ausgabe 1/2019
Print ISSN: 1633-8065
Elektronische ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-018-2286-8

Weitere Artikel der Ausgabe 1/2019

European Journal of Orthopaedic Surgery & Traumatology 1/2019 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.