Anti-inflammatory effect of Acacia visco extracts in animal models
- 01.10.2010
- Research Article
Erschienen in:
- Verfasst von
- Ana María Pedernera
- Teresita Guardia
- Carola Elisa Guardia Calderón
- Alejandra Ester Rotelli
- Nadir Ernesto de la Rocha
- José Roberto Saad
- María Alejandra Lopez Verrilli
- Susana Garcia Aseff
- Lilian Eugenia Pelzer
- Erschienen in
- Inflammopharmacology | Ausgabe 5/2010
Abstract
The aqueous and organic extracts of Acacia visco Lor. Ap Griseb (Fabaceae) were tested for anti-inflammatory activity in experimental models in rat. Besides, the free-radical scavenging capacity of extracts from A. visco was determined. The extracts revealed anti-inflammatory effect against carrageenan-induced oedema, phospholipase A2-induced oedema, cotton pellet-induced granuloma and they did not show acute toxic effect. Among the class of compounds characterized from A. visco leaves, the triterpenoid 20(29)-lupen-3β-ol (lupeol), 12-ursen-3β-ol (α-amyrin) and 12-oleanen-3β-ol (β-amyrin) may be mainly responsible for the pharmacological activities.
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- Titel
- Anti-inflammatory effect of Acacia visco extracts in animal models
- Verfasst von
-
Ana María Pedernera
Teresita Guardia
Carola Elisa Guardia Calderón
Alejandra Ester Rotelli
Nadir Ernesto de la Rocha
José Roberto Saad
María Alejandra Lopez Verrilli
Susana Garcia Aseff
Lilian Eugenia Pelzer
- Publikationsdatum
- 01.10.2010
- Verlag
- SP Birkhäuser Verlag Basel
- Erschienen in
-
Inflammopharmacology / Ausgabe 5/2010
Print ISSN: 0925-4692
Elektronische ISSN: 1568-5608 - DOI
- https://doi.org/10.1007/s10787-009-0028-6
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