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01.10.2010 | Research Article

Anti-inflammatory effect of Acacia visco extracts in animal models

verfasst von: Ana María Pedernera, Teresita Guardia, Carola Elisa Guardia Calderón, Alejandra Ester Rotelli, Nadir Ernesto de la Rocha, José Roberto Saad, María Alejandra Lopez Verrilli, Susana Garcia Aseff, Lilian Eugenia Pelzer

Erschienen in: Inflammopharmacology | Ausgabe 5/2010

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Abstract

The aqueous and organic extracts of Acacia visco Lor. Ap Griseb (Fabaceae) were tested for anti-inflammatory activity in experimental models in rat. Besides, the free-radical scavenging capacity of extracts from A. visco was determined. The extracts revealed anti-inflammatory effect against carrageenan-induced oedema, phospholipase A₂-induced oedema, cotton pellet-induced granuloma and they did not show acute toxic effect. Among the class of compounds characterized from A. visco leaves, the triterpenoid 20(29)-lupen-3β-ol (lupeol), 12-ursen-3β-ol (α-amyrin) and 12-oleanen-3β-ol (β-amyrin) may be mainly responsible for the pharmacological activities.

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Titel: Anti-inflammatory effect of Acacia visco extracts in animal models
verfasst von: Ana María Pedernera
Teresita Guardia
Carola Elisa Guardia Calderón
Alejandra Ester Rotelli
Nadir Ernesto de la Rocha
José Roberto Saad
María Alejandra Lopez Verrilli
Susana Garcia Aseff
Lilian Eugenia Pelzer
Publikationsdatum: 01.10.2010
Verlag: SP Birkhäuser Verlag Basel
Erschienen in: Inflammopharmacology / Ausgabe 5/2010
Print ISSN: 0925-4692
Elektronische ISSN: 1568-5608
DOI: https://doi.org/10.1007/s10787-009-0028-6

Springer Medizin

Abstract

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