Skip to main content
main-content

01.12.2016 | Research | Ausgabe 1/2016 Open Access

European Journal of Medical Research 1/2016

Association between hypertension and deep vein thrombosis after orthopedic surgery: a meta-analysis

Zeitschrift:
European Journal of Medical Research > Ausgabe 1/2016
Autoren:
Lei Huang, Jie Li, Yong Jiang

Abstract

Background

We aimed to analyze the association between hypertension and deep vein thrombosis (DVT) after orthopedic surgery.

Methods

Relevant studies were identified by a search of PubMed, Embase, China National Knowledge Infrastructure, Wanfang, the Chinese Biomedical Literature, and Weipu database until December 2015. The association between hypertension and DVT after orthopedic surgery was assessed by pooled odds ratios (ORs) and 95 % confidence intervals (CIs). Heterogeneity was evaluated by the Chi-square test based on Q statistic and I 2 statistics. Finally, publication bias was evaluated by Egger’s test.

Results

A total of 16 articles with 68,955 males and 53,057 females were eventually identified. Studies yielded effects for homogeneous (Q = 38.41, P = 0.0008, and I 2 = 60.9 %). Meta-analysis showed that hypertension was associated with DVT orthopedic surgery (OR 2.89, 95 % CI 2.18–3.83, Z = 7.38, P < 0.05). No statistical evidence of publication bias was found among studies (t = 1.90, P = 0.08). The funnel plot was symmetry, and the results were reliable.

Conclusions

Hypertension may promote DVT after orthopedic surgery, and may be an important risk factor of DVT occurrence.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2016

European Journal of Medical Research 1/2016 Zur Ausgabe