Erschienen in:
01.02.2012 | EDITOR'S COMMENTARY
Attaining fluency in bioinformatics—the gremlins are coming!
verfasst von:
David F. Albertini
Erschienen in:
Journal of Assisted Reproduction and Genetics
|
Ausgabe 2/2012
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Excerpt
In the field of human ARTs, searching for reliable sentinels of “good” embryo or gamete health has not come easily. While the “looks are deceiving” argument has been expounded upon in the likes of JARG, Fertility and Sterility, and many companion journals, the quest for quantifiable and practical measures used for predicting embryo implantation and term gestation resembles more a litany of lost causes than one of crowning achievements. Moving beyond the realm of the subjective, which has punctuated the history of human IVF from the mid-1980s (How does your cumulus look? What was your embryo score?), through the 1990s, when ICSI took hold (How does your sperm look?)—to the present, when the reality of obtaining a running account of embryo behavior from fertilization to transfer now falls under the purview of those clinics who believe in (and can afford) the value of time-lapse imaging to make a coherent and repeatable decision that will benefit the patient. Such are the markings and marketings of morphological assessments brought into the fourth dimension-time! …