Skip to main content
Erschienen in: Supportive Care in Cancer 6/2018

15.12.2017 | Original Article

Attitudes towards end-of-life issues in intensive care unit among Italian anesthesiologists: a nation-wide survey

verfasst von: Andrea Cortegiani, Vincenzo Russotto, Santi Maurizio Raineri, Cesare Gregoretti, Antonino Giarratano, Sebastiano Mercadante

Erschienen in: Supportive Care in Cancer | Ausgabe 6/2018

Einloggen, um Zugang zu erhalten

Abstract

Background

The aim of this paper is to collect data on the practice of palliative care, withholding and withdrawal of life-sustaining therapies, and management of end of life (EOL) in Italian intensive care units (ICUs).

Methods

Web-based survey among Italian anesthesiologists endorsed by the Italian Society of Anesthesiology Analgesia Reanimation and Intensive Care (SIAARTI). The survey consists of 27 close-ended and 2 open-ended questions.

Results

Eight hundred and five persons responded to the full list of questions. The highest proportion of respondents was of 36–45 years of age (34%) and catholic (66%). Almost 70% of responders declared that palliative/supportive care are applied in their ICU in case of futility of intensive treatments. Decision on withdrawing/withholding of life-sustaining treatments resulted from team consensus in most cases (58%). In more than 70% of responders’ ICUs, there is no collaboration with palliative/supportive care experts. Systematic recording of most frequent symptoms experienced by critically ill patients (e.g., pain, dyspnea, thirst) was not common. Vasopressors, extracorporeal therapies, blood component transfusions and invasive monitoring were the most commonly modified/interrupted measures in case of futility. Almost 85% of respondents have not received training in palliative/supportive care. The proportion of respondents whose institution has a palliative care team and who had training in palliative care was not homogenous across the country.

Conclusions

These data suggest that training in palliative care and its clinical application should be implemented in Italy. Efforts should be made to improve and homogenize the management of dying patients in ICU.
Literatur
2.
Zurück zum Zitat Bosslet GT, Pope TM, Rubenfeld GD, Lo B, Truog RD, Rushton CH, Curtis JR, Ford DW, Osborne M, Misak C, Au DH, Azoulay E, Brody B, Fahy BG, Hall JB, Kesecioglu J, Kon AA, Lindell KO, White DB, American Thoracic Society ad hoc Committee on Futile and Potentially Inappropriate Treatment, American Thoracic Society, American Association for Critical Care Nurses, American College of Chest Physicians, European Society for Intensive Care Medicine, Society of Critical Care (2015) An official ATS/AACN/ACCP/ESICM/SCCM policy statement: responding to requests for potentially inappropriate treatments in intensive care units. Am J Respir Crit Care Med 191(11):1318–1330. https://doi.org/10.1164/rccm.201505-0924ST CrossRefPubMed Bosslet GT, Pope TM, Rubenfeld GD, Lo B, Truog RD, Rushton CH, Curtis JR, Ford DW, Osborne M, Misak C, Au DH, Azoulay E, Brody B, Fahy BG, Hall JB, Kesecioglu J, Kon AA, Lindell KO, White DB, American Thoracic Society ad hoc Committee on Futile and Potentially Inappropriate Treatment, American Thoracic Society, American Association for Critical Care Nurses, American College of Chest Physicians, European Society for Intensive Care Medicine, Society of Critical Care (2015) An official ATS/AACN/ACCP/ESICM/SCCM policy statement: responding to requests for potentially inappropriate treatments in intensive care units. Am J Respir Crit Care Med 191(11):1318–1330. https://​doi.​org/​10.​1164/​rccm.​201505-0924ST CrossRefPubMed
10.
Zurück zum Zitat Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS, RECOVER Program Investigators (Phase 1: towards RECOVER), Canadian Critical Care Trials Group (2016) One-year outcomes in caregivers of critically ill patients. N Engl J Med 374(19):1831–1841. https://doi.org/10.1056/NEJMoa1511160 CrossRefPubMed Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS, RECOVER Program Investigators (Phase 1: towards RECOVER), Canadian Critical Care Trials Group (2016) One-year outcomes in caregivers of critically ill patients. N Engl J Med 374(19):1831–1841. https://​doi.​org/​10.​1056/​NEJMoa1511160 CrossRefPubMed
12.
Zurück zum Zitat Frontera JA, Curtis JR, Nelson JE, Campbell M, Gabriel M, Mosenthal AC, Mulkerin C, Puntillo KA, Ray DE, Bassett R, Boss RD, Lustbader DR, Brasel KJ, Weiss SP, Weissman DE, Improving Palliative Care in the ICU Project Advisory Board (2015) Integrating palliative care into the care of neurocritically ill patients: a report from the improving palliative care in the ICU project advisory board and the center to advance palliative care. Crit Care Med 43(9):1964–1977. https://doi.org/10.1097/CCM.0000000000001131 CrossRefPubMedPubMedCentral Frontera JA, Curtis JR, Nelson JE, Campbell M, Gabriel M, Mosenthal AC, Mulkerin C, Puntillo KA, Ray DE, Bassett R, Boss RD, Lustbader DR, Brasel KJ, Weiss SP, Weissman DE, Improving Palliative Care in the ICU Project Advisory Board (2015) Integrating palliative care into the care of neurocritically ill patients: a report from the improving palliative care in the ICU project advisory board and the center to advance palliative care. Crit Care Med 43(9):1964–1977. https://​doi.​org/​10.​1097/​CCM.​0000000000001131​ CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Mosenthal AC, Weissman DE, Curtis JR, Hays RM, Lustbader DR, Mulkerin C, Puntillo KA, Ray DE, Bassett R, Boss RD, Brasel KJ, Campbell M, Nelson JE (2012) Integrating palliative care in the surgical and trauma intensive care unit: a report from the improving palliative care in the intensive care unit (IPAL-ICU) project advisory board and the center to advance palliative care. Crit Care Med 40(4):1199–1206. https://doi.org/10.1097/CCM.0b013e31823bc8e7 CrossRefPubMedPubMedCentral Mosenthal AC, Weissman DE, Curtis JR, Hays RM, Lustbader DR, Mulkerin C, Puntillo KA, Ray DE, Bassett R, Boss RD, Brasel KJ, Campbell M, Nelson JE (2012) Integrating palliative care in the surgical and trauma intensive care unit: a report from the improving palliative care in the intensive care unit (IPAL-ICU) project advisory board and the center to advance palliative care. Crit Care Med 40(4):1199–1206. https://​doi.​org/​10.​1097/​CCM.​0b013e31823bc8e7​ CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Nelson JE, Bassett R, Boss RD, Brasel KJ, Campbell ML, Cortez TB, Curtis JR, Lustbader DR, Mulkerin C, Puntillo KA, Ray DE, Weissman DE, Improve Palliative Care in the Intensive Care Unit Project (2010) Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: a report from the IPAL-ICU project (improving palliative care in the ICU). Crit Care Med 38(9):1765–1772. https://doi.org/10.1097/CCM.0b013e3181e8ad23 CrossRefPubMedPubMedCentral Nelson JE, Bassett R, Boss RD, Brasel KJ, Campbell ML, Cortez TB, Curtis JR, Lustbader DR, Mulkerin C, Puntillo KA, Ray DE, Weissman DE, Improve Palliative Care in the Intensive Care Unit Project (2010) Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: a report from the IPAL-ICU project (improving palliative care in the ICU). Crit Care Med 38(9):1765–1772. https://​doi.​org/​10.​1097/​CCM.​0b013e3181e8ad23​ CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Davidson JE, Aslakson RA, Long AC, Puntillo KA, Kross EK, Hart J, Cox CE, Wunsch H, Wickline MA, Nunnally ME, Netzer G, Kentish-Barnes N, Sprung CL, Hartog CS, Coombs M, Gerritsen RT, Hopkins RO, Franck LS, Skrobik Y, Kon AA, Scruth EA, Harvey MA, Lewis-Newby M, White DB, Swoboda SM, Cooke CR, Levy MM, Azoulay E, Curtis JR (2017) Guidelines for family-centered care in the neonatal, pediatric, and adult ICU. Crit Care Med 45(1):103–128. https://doi.org/10.1097/CCM.0000000000002169 CrossRefPubMed Davidson JE, Aslakson RA, Long AC, Puntillo KA, Kross EK, Hart J, Cox CE, Wunsch H, Wickline MA, Nunnally ME, Netzer G, Kentish-Barnes N, Sprung CL, Hartog CS, Coombs M, Gerritsen RT, Hopkins RO, Franck LS, Skrobik Y, Kon AA, Scruth EA, Harvey MA, Lewis-Newby M, White DB, Swoboda SM, Cooke CR, Levy MM, Azoulay E, Curtis JR (2017) Guidelines for family-centered care in the neonatal, pediatric, and adult ICU. Crit Care Med 45(1):103–128. https://​doi.​org/​10.​1097/​CCM.​0000000000002169​ CrossRefPubMed
18.
Zurück zum Zitat Zalenski RJ, Jones SS, Courage C, Waselewsky DR, Kostaroff AS, Kaufman D, Beemath A, Brofman J, Castillo JW, Krayem H, Marinelli A, Milner B, Palleschi MT, Tareen M, Testani S, Soubani A, Walch J, Wheeler J, Wilborn S, Granovsky H, Welch RD (2017) Impact of palliative care screening and consultation in the ICU: a multihospital quality improvement project. J Pain Symptom Manag 53(1):5–12.e3. https://doi.org/10.1016/j.jpainsymman.2016.08.003 CrossRef Zalenski RJ, Jones SS, Courage C, Waselewsky DR, Kostaroff AS, Kaufman D, Beemath A, Brofman J, Castillo JW, Krayem H, Marinelli A, Milner B, Palleschi MT, Tareen M, Testani S, Soubani A, Walch J, Wheeler J, Wilborn S, Granovsky H, Welch RD (2017) Impact of palliative care screening and consultation in the ICU: a multihospital quality improvement project. J Pain Symptom Manag 53(1):5–12.e3. https://​doi.​org/​10.​1016/​j.​jpainsymman.​2016.​08.​003 CrossRef
22.
Zurück zum Zitat Myatra SN, Salins N, Iyer S, Macaden SC, Divatia JV, Muckaden M, Kulkarni P, Simha S, Mani RK (2014) End-of-life care policy: an integrated care plan for the dying: a joint position statement of the Indian Society of Critical Care Medicine (ISCCM) and the Indian Association of Palliative Care (IAPC). Indian J Crit Care Med 18(9):615–635. https://doi.org/10.4103/0972-5229.140155 CrossRefPubMedPubMedCentral Myatra SN, Salins N, Iyer S, Macaden SC, Divatia JV, Muckaden M, Kulkarni P, Simha S, Mani RK (2014) End-of-life care policy: an integrated care plan for the dying: a joint position statement of the Indian Society of Critical Care Medicine (ISCCM) and the Indian Association of Palliative Care (IAPC). Indian J Crit Care Med 18(9):615–635. https://​doi.​org/​10.​4103/​0972-5229.​140155 CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Truog RD, Campbell ML, Curtis JR, Haas CE, Luce JM, Rubenfeld GD, Rushton CH, Kaufman DC, American Academy of Critical Care Medicine (2008) Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American college [corrected] of critical care medicine. Crit Care Med 36(3):953–963. https://doi.org/10.1097/CCM.0B013E3181659096 CrossRefPubMed Truog RD, Campbell ML, Curtis JR, Haas CE, Luce JM, Rubenfeld GD, Rushton CH, Kaufman DC, American Academy of Critical Care Medicine (2008) Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American college [corrected] of critical care medicine. Crit Care Med 36(3):953–963. https://​doi.​org/​10.​1097/​CCM.​0B013E3181659096​ CrossRefPubMed
26.
Zurück zum Zitat Lanken PN, Terry PB, Delisser HM, Fahy BF, Hansen-Flaschen J, Heffner JE, Levy M, Mularski RA, Osborne ML, Prendergast TJ, Rocker G, Sibbald WJ, Wilfond B, Yankaskas JR, ATS End-of-Life Care Task Force (2008) An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses. Am J Respir Crit Care Med 177(8):912–927. https://doi.org/10.1164/rccm.200605-587ST CrossRefPubMed Lanken PN, Terry PB, Delisser HM, Fahy BF, Hansen-Flaschen J, Heffner JE, Levy M, Mularski RA, Osborne ML, Prendergast TJ, Rocker G, Sibbald WJ, Wilfond B, Yankaskas JR, ATS End-of-Life Care Task Force (2008) An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses. Am J Respir Crit Care Med 177(8):912–927. https://​doi.​org/​10.​1164/​rccm.​200605-587ST CrossRefPubMed
28.
Zurück zum Zitat Myburgh J, Abillama F, Chiumello D, Dobb G, Jacobe S, Kleinpell R, Koh Y, Martin C, Michalsen A, Pelosi P, Torra LB, Vincent JL, Yeager S, Zimmerman J, Council of the World Federation of Societies of Intensive and Critical Care Medicine (2016) End-of-life care in the intensive care unit: report from the task force of world Federation of Societies of intensive and critical care medicine. J Crit Care 34:125–130. https://doi.org/10.1016/j.jcrc.2016.04.017 CrossRefPubMed Myburgh J, Abillama F, Chiumello D, Dobb G, Jacobe S, Kleinpell R, Koh Y, Martin C, Michalsen A, Pelosi P, Torra LB, Vincent JL, Yeager S, Zimmerman J, Council of the World Federation of Societies of Intensive and Critical Care Medicine (2016) End-of-life care in the intensive care unit: report from the task force of world Federation of Societies of intensive and critical care medicine. J Crit Care 34:125–130. https://​doi.​org/​10.​1016/​j.​jcrc.​2016.​04.​017 CrossRefPubMed
30.
Zurück zum Zitat (2006) End-of-life care and the intensivist: SIAARTI recommendations on the management of the dying patient. Minerva Anestesiol 72(12):927–963 (2006) End-of-life care and the intensivist: SIAARTI recommendations on the management of the dying patient. Minerva Anestesiol 72(12):927–963
32.
Zurück zum Zitat Puntillo K, Nelson JE, Weissman D, Curtis R, Weiss S, Frontera J, Gabriel M, Hays R, Lustbader D, Mosenthal A, Mulkerin C, Ray D, Bassett R, Boss R, Brasel K, Campbell M, Advisory Board of the Improving Palliative Care in the ICU (IPAL-ICU) Project (2014) Palliative care in the ICU: relief of pain, dyspnea, and thirst—a report from the IPAL-ICU Advisory Board. Intensive Care Med 40(2):235–248. https://doi.org/10.1007/s00134-013-3153-z CrossRefPubMed Puntillo K, Nelson JE, Weissman D, Curtis R, Weiss S, Frontera J, Gabriel M, Hays R, Lustbader D, Mosenthal A, Mulkerin C, Ray D, Bassett R, Boss R, Brasel K, Campbell M, Advisory Board of the Improving Palliative Care in the ICU (IPAL-ICU) Project (2014) Palliative care in the ICU: relief of pain, dyspnea, and thirst—a report from the IPAL-ICU Advisory Board. Intensive Care Med 40(2):235–248. https://​doi.​org/​10.​1007/​s00134-013-3153-z CrossRefPubMed
35.
Zurück zum Zitat Mercadante S, Vitrano V (2010) Palliative care in Italy: problem areas emerging from the literature. Minerva Anestesiol 76(12):1060–1071PubMed Mercadante S, Vitrano V (2010) Palliative care in Italy: problem areas emerging from the literature. Minerva Anestesiol 76(12):1060–1071PubMed
41.
Zurück zum Zitat Ho KM, Liang J (2004) Withholding and withdrawal of therapy in New Zealand intensive care units (ICUs): a survey of clinical directors. Anaesth Intensive Care 32(6):781–786CrossRefPubMed Ho KM, Liang J (2004) Withholding and withdrawal of therapy in New Zealand intensive care units (ICUs): a survey of clinical directors. Anaesth Intensive Care 32(6):781–786CrossRefPubMed
43.
Zurück zum Zitat Kranidiotis G, Gerovasili V, Tasoulis A, Tripodaki E, Vasileiadis I, Magira E, Markaki V, Routsi C, Prekates A, Kyprianou T, Clouva-Molyvdas PM, Georgiadis G, Floros I, Karabinis A, Nanas S (2010) End-of-life decisions in Greek intensive care units: a multicenter cohort study. Crit Care 14(6):R228. https://doi.org/10.1186/cc9380 CrossRefPubMedPubMedCentral Kranidiotis G, Gerovasili V, Tasoulis A, Tripodaki E, Vasileiadis I, Magira E, Markaki V, Routsi C, Prekates A, Kyprianou T, Clouva-Molyvdas PM, Georgiadis G, Floros I, Karabinis A, Nanas S (2010) End-of-life decisions in Greek intensive care units: a multicenter cohort study. Crit Care 14(6):R228. https://​doi.​org/​10.​1186/​cc9380 CrossRefPubMedPubMedCentral
Metadaten
Titel
Attitudes towards end-of-life issues in intensive care unit among Italian anesthesiologists: a nation-wide survey
verfasst von
Andrea Cortegiani
Vincenzo Russotto
Santi Maurizio Raineri
Cesare Gregoretti
Antonino Giarratano
Sebastiano Mercadante
Publikationsdatum
15.12.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 6/2018
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-017-4014-z

Weitere Artikel der Ausgabe 6/2018

Supportive Care in Cancer 6/2018 Zur Ausgabe

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.