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Erschienen in: Rheumatology International 3/2010

01.01.2010 | Original Article

Autoimmune joint diseases in Late Medieval skeletal sample from Croatia

verfasst von: Petra Rajić Šikanjić, Dejana Vlak

Erschienen in: Rheumatology International | Ausgabe 3/2010

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Abstract

Analysis of 25 skeletons from Late Medieval cemetery Uzdolje-Grablje near Knin, Croatia, revealed three cases of systematic pathological changes to joints. Observed pathological lesions were examined macroscopically and radiologically and compared to the available paleopathological standards in order to formulate a differential diagnosis. In all three cases observed changes were most consistent with autoimmune joint diseases including ankylosing spondylitis, juvenile idiopathic arthritis and psoriatic arthritis. Based on published clinical studies, we suggest that the high prevalence of autoimmune diseases in our skeletal sample stems from the genetic basis of the autoimmunity, and that three individuals describe here are possibly closely related.
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Metadaten
Titel
Autoimmune joint diseases in Late Medieval skeletal sample from Croatia
verfasst von
Petra Rajić Šikanjić
Dejana Vlak
Publikationsdatum
01.01.2010
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 3/2010
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-009-0968-6

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