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Clinical & Translational Metabolism

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01.06.2014 | Original Paper

Bone and Muscle Pleiotropy: The Genetics of Associated Traits

verfasst von: Robert D. Blank

Erschienen in: Clinical & Translational Metabolism | Ausgabe 2/2014

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Abstract

Bone and muscle mass are highly correlated. In part, this is a consequence of both tissues sharing common genetic determinants. In addition, both tissues are responsive to their mechanical environments. New genetic tools in mice will allow genes of interest to be inactivated in experimentally defined contexts, thus allowing investigators to distinguish direct effects on each tissue from physiological responses to a primary phenotype in the other.

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Titel: Bone and Muscle Pleiotropy: The Genetics of Associated Traits
verfasst von: Robert D. Blank
Publikationsdatum: 01.06.2014
Verlag: Springer US
Erschienen in: Clinical & Translational Metabolism / Ausgabe 2/2014
Print ISSN: 1534-8644
Elektronische ISSN: 2948-2445
DOI: https://doi.org/10.1007/s12018-014-9159-4

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