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European Journal of Epidemiology
Erschienen in: European Journal of Epidemiology 1/2012

01.01.2012 | COMMENTARY

Breast cancer following diethylstilbestrol exposure in utero: insights from a tragedy

verfasst von: Hans-Olov Adami, Pagona Lagiou, Dimitrios Trichopoulos

Erschienen in: European Journal of Epidemiology | Ausgabe 1/2012

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Abstract

Diethylstilbestrol (DES), a powerful synthetic estrogen introduced in 1938, was prescribed to prevent pregnancy complications, but was later shown to have a series of adverse side-effects in the offspring, including cancer of the vagina. Recent evidence indicates that in utero exposure to DES is also linked to breast cancer in women over the age of 40 years. This evidence provides support to the hypothesis that in utero exposures may affect breast cancer risk in adult life.
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Metadaten
Titel
Breast cancer following diethylstilbestrol exposure in utero: insights from a tragedy
verfasst von
Hans-Olov Adami
Pagona Lagiou
Dimitrios Trichopoulos
Publikationsdatum
01.01.2012
Verlag
Springer Netherlands
Erschienen in
European Journal of Epidemiology / Ausgabe 1/2012
Print ISSN: 0393-2990
Elektronische ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-012-9655-0

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