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01.12.2018 | Case report | Ausgabe 1/2018 Open Access

BMC Infectious Diseases 1/2018

Case report: detection of the identical virus in a patient presenting with severe fever with thrombocytopenia syndrome encephalopathy and the tick that bit her

Zeitschrift:
BMC Infectious Diseases > Ausgabe 1/2018
Autoren:
Uh. Jin Kim, Dong-Min Kim, Seong Eun Kim, Seung Ji Kang, Hee-Chang Jang, Kyung-Hwa Park, Sook In Jung

Abstract

Background

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease. Haemophysalis longicornis ticks have been considered the vector of severe fever with thrombocytopenia syndrome virus (SFTSV). However, clear data on the transmission of SFTS from ticks to humans are limited.

Case presentation

We report an 84-year-old woman who presented with fever and altered mentality, which was confirmed as SFTS with encephalopathy by reverse-transcription polymerase chain reaction in blood and cerebrospinal fluid. The SFTSV was also identified in the tick that bit her, H. longicornis. Phylogenetic analyses indicated that the SFTSV from the patient and the tick was identical. The patient gradually recovered with treatments of corticosteroids and immunoglobulin.

Conclusion

These findings provide further evidence of SFTS viral transmission from H. longicornis to human.
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