Skip to main content
main-content

01.12.2012 | Case report | Ausgabe 1/2012 Open Access

Journal of Medical Case Reports 1/2012

Central syntropic effects elicited by trigeminal proprioceptive equilibrium in Alzheimer’s disease: a case report

Zeitschrift:
Journal of Medical Case Reports > Ausgabe 1/2012
Autor:
Vincenzo De Cicco
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-6-161) contains supplementary material, which is available to authorized users.

Competing interests

The author declares that he has no competing interests.

Abstract

Introduction

The presented patient, affected by Alzheimer’s disease, underwent neuropsychological evaluation and functional magnetic resonance imaging investigation under occlusal proprioceptive un-balance and re-balance conditions. Saccadic and pupillometric video-oculographic examinations were performed in order to detect connected trigeminal proprioceptive motor patterns able to interfere with reticular formation cerebellum functions linked to visual and procedural processes prematurely altered in Alzheimer’s disease.

Case presentation

A 66-year-old Caucasian man, affected by Alzheimer’s disease and with a neuropsychological evaluation issued by the Alzheimer’s Evaluation Unit, underwent an electromyographic investigation of the masseter muscles in order to assess their functional balance. The patient showed a bilateral lack of all inferior molars. The extreme myoelectric asymmetry in dental occlusion suggested the rebalancing of masseter muscular functions through concurrent transcutaneous stimulation of the trigeminal nerve supramandibular and submandibular motor branches. The above-mentioned method allows detection of symmetric craniomandibular muscular relation that can be kept constant through the use of a cusp bite modeled on the inferior dental arch, called orthotic-syntropic bite. A few days later, the patient underwent a new neuropsychological investigation, together with a functional magnetic resonance imaging study, and saccadic, pupillometric video-oculographic examinations in occlusal un-balance and re-balance conditions.

Conclusions

Comparative data analysis has shown that a re-balanced occlusal condition can improve a patient’s cognitive-attentive functions. Moreover, the saccadic and pupillometric video-oculographic investigations have proven useful both in analyzing reticulo-cerebellar subcortical systems, prematurely altered in Alzheimer’s disease, and in implementing neurological evaluations.

Unsere Produktempfehlungen

e.Med Interdisziplinär

Kombi-Abonnement

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

e.Med Allgemeinmedizin

Kombi-Abonnement

Mit e.Med Allgemeinmedizin erhalten Sie Zugang zu allen CME-Fortbildungen und Premium-Inhalten der allgemeinmedizinischen Zeitschriften, inklusive einer gedruckten Allgemeinmedizin-Zeitschrift Ihrer Wahl.​​​​​​​​​​​​​​

Zusatzmaterial
Authors’ original file for figure 1
13256_2011_2124_MOESM1_ESM.pdf
Authors’ original file for figure 2
13256_2011_2124_MOESM2_ESM.pdf
Authors’ original file for figure 3
13256_2011_2124_MOESM3_ESM.pdf
Authors’ original file for figure 4
13256_2011_2124_MOESM4_ESM.pdf
Authors’ original file for figure 5
13256_2011_2124_MOESM5_ESM.pdf
Authors’ original file for figure 6
13256_2011_2124_MOESM6_ESM.pdf
Authors’ original file for figure 7
13256_2011_2124_MOESM7_ESM.pdf
Authors’ original file for figure 8
13256_2011_2124_MOESM8_ESM.pdf
Authors’ original file for figure 9
13256_2011_2124_MOESM9_ESM.pdf
Authors’ original file for figure 10
13256_2011_2124_MOESM10_ESM.pdf
Authors’ original file for figure 11
13256_2011_2124_MOESM11_ESM.pdf
Authors’ original file for figure 12
13256_2011_2124_MOESM12_ESM.pdf
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2012

Journal of Medical Case Reports 1/2012 Zur Ausgabe