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Endocrine

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01.04.2013 | Research Letter

Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism

verfasst von: Shweta Varshney, Sanjay Kumar Bhadada, Uma Nahar, Viral N. Shah, Anil Bhansali, Arnanshu Behera

Erschienen in: Endocrine | Ausgabe 2/2013

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Excerpt

Primary hyperparathyroidism (PHPT) is a common endocrine disorder and the most common cause of PHPT is parathyroid adenoma [1]. The normal parathyroid gland is composed of three types of cells—chief (50–60 %), clear (30–40 %), and oxyphil cells (<5 %) [2]. The chief cells have slightly eosinophilic cytoplasm and contain few mitochondria and these cells mainly secrete parathyroid hormone (PTH) [2]. Clear cells, which contain excessive cytoplasmic glycogen, are formed from chief cells while oxyphil cells have an intensely eosinophilic cytoplasm enriched with numerous and tightly packed mitochondria [3]. The function of clear and oxyphil cells is still not clear [2, 3]. …

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Titel: Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism
verfasst von: Shweta Varshney
Sanjay Kumar Bhadada
Uma Nahar
Viral N. Shah
Anil Bhansali
Arnanshu Behera
Publikationsdatum: 01.04.2013
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 2/2013
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-012-9810-0

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Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism

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