Erschienen in:
13.10.2016 | Research Letter
Circulating periostin in patients with nonalcoholic fatty liver disease
verfasst von:
Stergios A. Polyzos, Jannis Kountouras, Athanasios D. Anastasilakis, Athanasios Papatheodorou, Panagiotis Kokkoris, Evangelos Terpos
Erschienen in:
Endocrine
|
Ausgabe 2/2017
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Excerpt
Nonalcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, ranges from nonalcoholic simple steatosis (SS) to nonalcoholic steatohepatitis (NASH), characterized by inflammation and/or fibrosis, and to NASH-related cirrhosis and hepatocellular carcinoma [
1]. Liver biopsy still is regarded as the reference for the diagnosis of NAFLD, although identification of noninvasive biomarkers is a field of intense research, expected to help both clinical trials and clinical practice, which are to date impaired due to the need of paired biopsies [
2]. …