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Clinical Oral Investigations

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01.03.2013 | Original Article

Clinical and microbiological effects of ozone nano-bubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial

verfasst von: Sae Hayakumo, Shinichi Arakawa, Yoshihiro Mano, Yuichi Izumi

Erschienen in: Clinical Oral Investigations | Ausgabe 2/2013

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Abstract

Aim

Ozone nano-bubble water (NBW3) seems to be suitable as an adjunct to periodontal treatment owing to its potent antimicrobial effects, high level of safety, and long storage stability. The aim of the present study was to evaluate the clinical and microbiological effects of NBW3 irrigation as an adjunct to subgingival debridement for periodontal treatment.

Methods

Twenty-two subjects were randomly assigned to one of the two treatment groups: full-mouth mechanical debridement with tap water (WATER) or full-mouth mechanical debridement with NBW3 (NBW3). Clinical examination was performed at baseline and 4 and 8 weeks after treatment. Microbiological examination was carried out just before and after treatment and at 1 and 8 weeks posttreatment.

Results

There were significant improvements in all clinical parameters after 4 weeks in both groups. The reduction in the probing pocket depth and the clinical attachment gain after 4 and 8 weeks in the NBW3 group were significantly greater than those in the WATER group. Moreover, only the NBW3 group showed statistically significant reductions in the mean total number of bacteria in subgingival plaque over the study period.

Conclusions

The present study suggests that subgingival irrigation with NBW3 may be a valuable adjunct to periodontal treatment.

Clinical relevance

This study verified the potential of new antimicrobial agent, MNW3, as an adjunct to periodontal treatment.

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Titel: Clinical and microbiological effects of ozone nano-bubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial
verfasst von: Sae Hayakumo
Shinichi Arakawa
Yoshihiro Mano
Yuichi Izumi
Publikationsdatum: 01.03.2013
Verlag: Springer-Verlag
Erschienen in: Clinical Oral Investigations / Ausgabe 2/2013
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-012-0711-7

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Abstract

Aim

Methods

Results

Conclusions

Clinical relevance

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