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Archives of Gynecology and Obstetrics

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01.05.2014 | Case Report

Complete hydatidiform mole and a coexistent fetus following ovulation induction in a patient with Sheehan’s syndrome: a first case report and review of literature

verfasst von: Xuekun Huang, Jingyao Liang, Yonghan Huang, Juanhua Huang

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 5/2014

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Abstract

Pregnancy in Sheehan’s syndrome (SS) is extremely rare. We present the first reported case of twin pregnancy with complete hydatiform mole (CHM) and a coexistent fetus (CHCF) in a patient with SS. A 29-year-old Chinese patient with SS became pregnant following one cycle of ovulation induction with human menopausal gonadotropin after secondary infertility. A normal live fetus and a low echogenic mass suspected hydatidiform mole (HM) were detected by ultrasound examinations at gestational week 8. The couple highly desired to continue the pregnancy because it is very hard to get pregnant for the patients with SS. However, the pregnancy was terminated for the size of the HM component increased rapidly at gestational week 15. Histological examinations confirmed CHCF. Genetic studies showed that the CHM genome was derived from paternal diploidy, and the normal fetus was from biparental genomes. Furthermore, a literature review on these topics is included. This case highlighted that even in a patient with SS, twin pregnancy with CHCF can still occur after ovulation induction.

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Titel: Complete hydatidiform mole and a coexistent fetus following ovulation induction in a patient with Sheehan’s syndrome: a first case report and review of literature
verfasst von: Xuekun Huang
Jingyao Liang
Yonghan Huang
Juanhua Huang
Publikationsdatum: 01.05.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 5/2014
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-013-3118-z

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