nach oben

Erschienen in:

01.09.2005 | Short Communication

Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study

verfasst von: Elio Castagnola, Giuseppe Fratino, Mariangela Valera, Mareva Giacchino, Riccardo Haupt, Angelo Claudio Molinari

Erschienen in: Supportive Care in Cancer | Ausgabe 9/2005

Einloggen, um Zugang zu erhalten

Abstract

Aim of the study

To evaluate the possible link between malfunctioning events and catheter related infections in indwelling central venous devices in children with cancer.

Patients and methods

Prospective observation of 418 devices inserted in 2 Italian tertiary care pediatric cancer centers. The presence of a relationship was identified if a malfunctioning event was followed by a catheter related infection within 10 days, or vice versa.

Results

The 418 catheters were followed for a period of 107,012 days. Among the malfunctioning events 2 out of 141 (1%) were followed by a catheter related infection while among infectious episodes 3 out of 93 (3%) were followed by a malfunctioning event.

Conclusions

Malfunctioning events followed by catheter related infections and catheter related infections followed by malfunctioning are both rare events in children with cancer.

Castagnola E, Molinari AC, Fratino G, Viscoli C (2003) Conditions associated with infections of indwelling central venous catheters in cancer patients: a summary. Br J Haematol 121:233–239PubMed

Crnich CJ, Maki DG (2002) The promise of novel technology for prevention of intravascular device related bloodstream infections. II. Long term devices. Clin Infect Dis 34:1362–1368

Darouiche RO (2001) Device associated infections: a macroproblem that starts with microadherence. Clin Infect Dis 33:1567–1572

De Pauw B, Meunier F (2000) Infections in patients with acute leukemia and lymphoma. In: Mandell GL, Bennett JB, Dolin R (eds) Mandell, Douglas and Bennett’s principles and practice of infectious diseases. Churchill Livingstone, Philadelphia, pp 3090–3102

Donlan RM (2001) Biofilm formation: a clinically relevant microbiological process. Clin Infect Dis 33:1387–1393

Fratino G, Mazzola C, Buffa P, Torre M, Castagnola E, Magillo P et al (2001) Mechanical complications related to indwelling central venous catheter in hematology/oncology patients. Pediatr Hematol Oncol 18:317–324

Fratino G, Molinari AC, Parodi S, Longo S, Saracco P, Castagnola E, Haupt R (2005) Central venous catheter related complications in children with oncological/hematological diseases: an observational study on 418 devices. Ann Oncol. [Epub ahead of print]

Journeycake JM, Buchanan GR (2003) Thrombotic complications of central venous catheters in children. Curr Opin Hematol 10:369–374

Mermel LA (2000) Prevention of intravascular catheter related infections. Ann Intern Med 132:391–402PubMed

10.

Molinari AC, Castagnola E, Mazzola C, Piacentino M, Fratino G (2001) Thromboembolic complications related to indwelling central venous catheters in children with oncological/haematological diseases: a retrospective study on 362 catheters. Support Care Cancer 9:539–544CrossRefPubMed

11.

O’Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Dennis G, Maki DG et al (2002) Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 35:1281–1307CrossRef

12.

Raad II, Luna M, Khalil SA, Costerton JW, Lam C, Bodey GP (1994) The relationship between the thrombotic and infectious complications of central venous catheters. JAMA 271:1014–1016

13.

Tolar B, Gould JR (1996) The timing and sequence of multiple device related complications in patients with long term indwelling Groshong catheters. Cancer 78:1308–1313

14.

Viscoli C, Castagnola E, Giacchino M, Cesaro S, Properzi E, Tucci F et al (1999) Bloodstream infections in children with cancer: a multicentre surveillance study of the Italian Association of Paediatric Haematology and Oncology. Supportive Therapy Group Infectious Diseases Section. Eur J Cancer 35:770–774CrossRefPubMed

Titel: Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study
verfasst von: Elio Castagnola
Giuseppe Fratino
Mariangela Valera
Mareva Giacchino
Riccardo Haupt
Angelo Claudio Molinari
Publikationsdatum: 01.09.2005
Verlag: Springer-Verlag
Erschienen in: Supportive Care in Cancer / Ausgabe 9/2005
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-005-0802-y

Springer Medizin

Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study