Background
Methods
Patient characteristics | Age, gender, co-morbiditya, GCSb, GOS, indication for DC, VP-shunt, 30-day mortality |
---|---|
Operative measurements | Operating time (CP), surgery prior to DC, implant type, time between DC and CP, fragmentation of bone flap |
Complications | SSI, wound dehiscence, BFR, hematoma, implant displacement |
Statistical analysis
Ethical considerations
Results
Variable | CP |
---|---|
Median age (years) | 31 (1-64) |
Male-n (%) | 54 (62) |
Preceding pathology-n (%) | |
- Trauma | 74 (85) |
- Stroke | 13 (15) |
Surgery prior to DC-n (%) | |
- None | 40 (46) |
- Craniotomy | 23 (26) |
- ICP and/or EVD | 24 (28) |
Implant - Autologous-n (%) | 77 (89) |
- Synthetic-n (%) | 10 (11) |
Median operating time (min) (range) | 85 (35-390) |
GOS level-n (%) | 2 = 16 (18) |
3 = 30 (35) | |
4 = 20 (23) | |
5 = 21 (24) | |
Complications-n (%) | |
- Wound dehiscence | 1 (1.1) |
- Implant dislodgement | 3 (3.4) |
- Intracranial hematoma | 5 (5.7) |
- SSI | 8 (9.2) |
- BFR (of 71 patients) | 14 (19.7) |
Complications
Variable | No BFR (n = 57) | BFR (n = 14) | Univariable OR (95 % CI) | Multivariable OR (95 % CI) |
---|---|---|---|---|
p-value | p-value | |||
Median age (range) (yrs) | 38 (14-65) | 26.5 (1.0-60) | 0.96 (0.92-1.00) | 0.94 (0.88-1.0) |
0.065 | 0.04 | |||
Gender - n male | 36 | 9 | 0.95 (0.28-3.22) | |
0.94 | ||||
Preceding pathology* -n | ||||
- Trauma | 48 | 10 | 0.47 (0.12-1.83) | |
- Stroke | 9 | 4 | 0.28 | |
Surgery prior to DC | 31/26 | 8/6 | 1.03 (0.63-1.68) | |
(yes/no) | 0.92 | |||
Fragmentation -n | 8 | 7 | 6.13 (1.69-22.2) | 14.3 (2.26-89) |
0.006 | 0.005 | |||
Median operating time (min) (range) | 81.5 (35-390) | 72.5 (51-164) | 0.99 (0.98-1.00) | |
0.27 | ||||
GOS at time of CP | ||||
2 | 14 | 0 | 2.2 (1.16-4.20) | 2.55 (1.04-6.23) |
3 | 19 | 4 | 0.02 | 0.04 |
4 | 14 | 4 | ||
5 | 10 | 6 | ||
Median time DC-CP (range) (days) | 70 (19-171) | 88 (48-353) | 1.02 (1.00-1.03) | 1.03 (1.00-1.04) |
0.02 | 0.02 | |||
Median GCS prior to DC | 6 | 8 | 1.12 (0.95-1.32) | |
0.19 | ||||
Registered co-morbidity -n | 13 | 4 | 1.01 (0.77-1.32) | |
0.93 | ||||
VP-shunt at time of CP -n | 5 | 2 | 1.73 (0.30-10.0) | |
0.54 |