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Current Fungal Infection Reports
Erschienen in: Current Fungal Infection Reports 4/2018

24.10.2018 | Current Management of Fungal Infections (J Maertens, Section Editor)

Cryptococcosis in Patients with Hematologic Diseases

verfasst von: Mariana Guarana, Jose Ernesto Vidal, Marcio Nucci

Erschienen in: Current Fungal Infection Reports | Ausgabe 4/2018

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Abstract

Purpose of Review

In this paper, we reviewed the epidemiology, diagnosis, and treatment of cryptococcosis in patients with hematologic malignancies. We reviewed all case series of cryptococcosis in different hematologic conditions, and looked at epidemiologic trends considering the new antineoplastic drugs introduced in the treatment of hematologic malignancies.

Recent Findings

Case series of cryptococcosis in patients with hematologic malignancies are scarce. We identified an increase in the proportion of cases of cryptococcosis occurring in patients with hematologic malignancies, and many case reports of cryptococcosis in patients receiving ibrutinib, a Bruton kinase inhibitor used in the treatment of chronic lymphoproliferative diseases.

Summary

Cryptococcosis is uncommon in patients with hematologic malignancies, but its occurrence may be associated with poor outcome. Hematologists should be aware of this complication if patients develop neurologic symptoms or present with pulmonary infiltrates that do not improve with antibiotics.
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Metadaten
Titel
Cryptococcosis in Patients with Hematologic Diseases
verfasst von
Mariana Guarana
Jose Ernesto Vidal
Marcio Nucci
Publikationsdatum
24.10.2018
Verlag
Springer US
Erschienen in
Current Fungal Infection Reports / Ausgabe 4/2018
Print ISSN: 1936-3761
Elektronische ISSN: 1936-377X
DOI
https://doi.org/10.1007/s12281-018-0332-y

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