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Erschienen in: Current Neurology and Neuroscience Reports 11/2013

01.11.2013 | Neurotrauma (J Levine, Section Editor)

Decompressive Craniectomy for Management of Traumatic Brain Injury: An Update

verfasst von: Leif-Erik Bohman, James M. Schuster

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 11/2013

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Abstract

Decompressive craniectomy (DC) for the management of severe traumatic brain injury (TBI) has a long history but remains controversial. Although DC has been shown to improve both survival and functional outcome in patients with malignant cerebral infarctions, evidence of benefit in patients with TBI is decidedly more mixed. Craniectomy can clearly be life-saving in the presence of medically intractable elevations of intracranial pressure. Craniectomy also has been consistently demonstrated to reduce “therapeutic intensity” in the ICU, to reduce the need for intracranial-pressure-directed and brain-oxygen-directed interventions, and to reduce ICU length of stay. Still, the only randomized trial of DC in TBI failed to demonstrate any benefit. Studies of therapies for TBI, including hemicraniectomy, are challenging owing to the inherent heterogeneity in the pathophysiology observed in this disease. Craniectomy can be life-saving for patients with severe TBI, but many questions remain regarding its ideal application, and the outcome remains highly correlated with the severity of the initial injury.
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Metadaten
Titel
Decompressive Craniectomy for Management of Traumatic Brain Injury: An Update
verfasst von
Leif-Erik Bohman
James M. Schuster
Publikationsdatum
01.11.2013
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 11/2013
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-013-0392-x

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