nach oben

European Journal of Epidemiology

Erschienen in:

01.09.2014 | COMMENTARY

Diagnosing overdiagnosis: conceptual challenges and suggested solutions

verfasst von: Bjorn Hofmann

Erschienen in: European Journal of Epidemiology | Ausgabe 9/2014

Einloggen, um Zugang zu erhalten

Excerpt

Overdiagnosis is a fundamental challenge to modern health care [1]. It is claimed to be “the biggest problem posed by modern medicine” [2], leading to unnecessary suffering and significant costs [1]. In the USA it is estimated that it results in more than $200bn wasted on unnecessary treatment every year [3], and that 30 % of the health care spending is on ineffective measures [4, 5]. …

Moynihan R, Doust J, Henry D. Preventing overdiagnosis: how to stop harming the healthy. BMJ. 2012;344:e3502. doi:10.1136/bmj.e3502.PubMedCrossRef

Welch HG, Schwartz L, Woloshin S. Overdiagnosed : making people sick in the pursuit of health. Boston: Beacon Press; 2011.

Berwick DM, Hackbarth AD. Eliminating waste in US health care. JAMA. 2012;307(14):1513–6. doi:10.1001/jama.2012.362.PubMedCrossRef

Bloche MG. Beyond the “R word”? Medicine’s new frugality. N Engl J Med. 2012;366(21):1951–3. doi:10.1056/NEJMp1203521.PubMedCrossRef

Fisher ES, Wennberg DE, Stukel TA, Gottlieb DJ, Lucas FL, Pinder EL. The implications of regional variations in medicare spending. Part 2: health outcomes and satisfaction with care. Ann Intern Med. 2003;138(4):288–98.PubMedCrossRef

Puliti D, Zappa M, Miccinesi G, Falini P, Crocetti E, Paci E. An estimate of overdiagnosis 15 years after the start of mammographic screening in Florence. Eur J Cancer. 2009;45(18):3166–71. doi:10.1016/j.ejca.2009.06.014.PubMedCrossRef

Jorgensen KJ, Zahl PH, Gotzsche PC. Overdiagnosis in organised mammography screening in Denmark. A comparative study. BMC Women’s Health. 2009;9:36. doi:10.1186/1472-6874-9-36.PubMedCrossRefPubMedCentral

de Gelder R, Heijnsdijk EA, van Ravesteyn NT, Fracheboud J, Draisma G, de Koning HJ. Interpreting overdiagnosis estimates in population-based mammography screening. Epidemiol Rev. 2011;33(1):111–21. doi:10.1093/epirev/mxr009.PubMedCrossRefPubMedCentral

Kalager M, Adami HO, Bretthauer M, Tamimi RM. Overdiagnosis of invasive breast cancer due to mammography screening: results from the Norwegian screening program. Ann Intern Med. 2012;156(7):491–9. doi:10.7326/0003-4819-156-7-201204030-00005.PubMedCrossRef

10.

Falk RS, Hofvind S, Skaane P, Haldorsen T. Overdiagnosis among women attending a population-based mammography screening program. Int J Cancer. 2013;133(3):705–12. doi:10.1002/ijc.28052.PubMedCrossRefPubMedCentral

11.

Welch HG, Passow HJ. Quantifying the benefits and harms of screening mammography. JAMA Intern Med. 2014;174(3):448–54. doi:10.1001/jamainternmed.2013.13635.PubMedCrossRef

12.

Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. Lancet. 2012;380(9855):1778–86. doi:10.1016/S0140-6736(12)61611-0.CrossRef

13.

Marmot MG, Altman DG, Cameron DA, Dewar JA, Thompson SG, Wilcox M. The benefits and harms of breast cancer screening: an independent review. Br J Cancer. 2013;108(11):2205–40. doi:10.1038/bjc.2013.177.PubMedCrossRefPubMedCentral

14.

International Agency for Research on Cancer (IARC). IARC handbooks of cancer prevention—breast cancer screening. Geneva: World Health Organisation; 2002.

15.

Welch HG, Black WC. Overdiagnosis in cancer. J Natl Cancer Inst. 2010;102(9):605–13. doi:10.1093/jnci/djq099.PubMedCrossRef

16.

Grobin W. Diabetes in the aged: underdiagnosis and overtreatment. Can Med Assoc J. 1970;103(9):915–23.PubMedPubMedCentral

17.

Feinstein AR, Esdaile JM. Incidence, prevalence, and evidence. Scientific problems in epidemiologic statistics for the occurrence of cancer. Am J Med. 1987;82(1):113–23.PubMedCrossRef

18.

Morrison A. Screening in chronic disease. New York: Oxford University Press; 1985.

19.

Black WC. Overdiagnosis: an underrecognized cause of confusion and harm in cancer screening. J Natl Cancer Inst. 2000;92(16):1280–2.PubMedCrossRef

20.

Etzioni R, Penson DF, Legler JM, et al. Overdiagnosis due to prostate-specific antigen screening: lessons from US prostate cancer incidence trends. J Natl Cancer Inst. 2002;94(13):981–90.PubMedCrossRef

21.

Hofmann B. The technological invention of disease—on disease, technology and values. Oslo: Universitetet i Oslo; 2002.

22.

King L. What is a disease? Philos Sci. 1954;21:193–203.CrossRef

23.

Reznek L. The nature of disease. New York: Routledge & Keagen Paul; 1987.

Titel: Diagnosing overdiagnosis: conceptual challenges and suggested solutions
verfasst von: Bjorn Hofmann
Publikationsdatum: 01.09.2014
Verlag: Springer Netherlands
Erschienen in: European Journal of Epidemiology / Ausgabe 9/2014
Print ISSN: 0393-2990
Elektronische ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-014-9920-5

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 9/2014

Early pregnancy exposure to antihistamines and risk of congenital heart defects: results of two case–control studies

Dairy foods intake and risk of Parkinson’s disease: a dose–response meta-analysis of prospective cohort studies

Not only the traumatic falls in elderly subjects requires awareness but all the falls even those hitherto regarded as unimportant

Recalibration of the SCORE risk chart for the Russian population

Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants

Quantifying the health benefits of chronic disease prevention: a fresh approach using cardiovascular disease as an example