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Annals of Nuclear Medicine

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01.09.2009 | Original Article

Diagnostic usefulness of ¹⁸F-FDG PET/CT in the differentiation of pulmonary artery sarcoma and pulmonary embolism

verfasst von: Kimiteru Ito, Kazuo Kubota, Miyako Morooka, Yoshitaka Shida, Kanehiro Hasuo, Hisako Endo, Hiroshi Matsuda

Erschienen in: Annals of Nuclear Medicine | Ausgabe 7/2009

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Abstract

Objective

The purpose of this study was to evaluate the usefulness of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in differentiating pulmonary artery sarcoma from pulmonary embolism.

Materials and methods

We evaluated three patients with pulmonary artery sarcoma and 10 patients with proximal pulmonary embolism (6 men and 7 women, ranging in age from 35 to 94 years). All the patients had evidence of perfusion defects in their proximal pulmonary arteries on contrast-enhanced computed tomography (CT) scans performed prior to PET/CT. The maximum standardized uptake value (SUV_max) of FDG uptake in all the lesions was measured using PET/CT. The location of lesions, background uptake or thrombi in the legs were evaluated in both groups as basic characteristics.

Results

The mean SUV_max of the pulmonary artery sarcomas (7.63 ± 2.21, n = 3) and the pulmonary embolisms (2.31 ± 0.41, n = 10) were significantly different (P < 0.05). The mean times between the initial contrast-enhanced CT scan and PET/CT scan were similar in both groups (P = 0.7804). The differences in the locations in lesions between the three groups (right, left and bilateral) or background uptakes were not significant.

Conclusion

FDG PET/CT could distinguish pulmonary artery sarcoma from pulmonary embolism based on the SUV_max value.

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Titel: Diagnostic usefulness of 18F-FDG PET/CT in the differentiation of pulmonary artery sarcoma and pulmonary embolism
verfasst von: Kimiteru Ito
Kazuo Kubota
Miyako Morooka
Yoshitaka Shida
Kanehiro Hasuo
Hisako Endo
Hiroshi Matsuda
Publikationsdatum: 01.09.2009
Verlag: Springer Japan
Erschienen in: Annals of Nuclear Medicine / Ausgabe 7/2009
Print ISSN: 0914-7187
Elektronische ISSN: 1864-6433
DOI: https://doi.org/10.1007/s12149-009-0292-y

Springer Medizin

Abstract

Objective

Materials and methods

Results

Conclusion

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