nach oben

Supportive Care in Cancer

Erschienen in:

01.07.2023 | Research

Dyadic effects of social support, illness uncertainty on anxiety and depression among lung cancer patients and their caregivers: a cross-sectional study

verfasst von: Tian Wang, Jiaojiao Sun, Danfeng Gu, Siwen Shen, Yunxu Zhou, Zhiqiang Wang

Erschienen in: Supportive Care in Cancer | Ausgabe 7/2023

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To explore the dyadic relationships between perceived social support, illness uncertainty, anxiety, and depression among lung cancer patients and their family caregivers. To examine the potential mediating role of illness uncertainty and the moderating role of disease stage in lung cancer patient-caregiver dyads.

Methods

A total of 308 pairs of lung cancer patients and their family caregivers from a tertiary hospital in Wuxi, China, from January 2022 to June 2022 were included. Participants’ perceived social support, illness uncertainty, anxiety, and depression were assessed by corresponding questionnaires. To test for dyadic relationships between the variables, we employed the actor-partner interdependence mediation model.

Results

There were actor and partner effects of both patient and caregiver perceived social support on anxiety and depression, and illness uncertainty mediated the effect of perceived social support on anxiety and depression. Lung cancer stage plays a moderating role in lung cancer patient-caregiver dyads. There is an indirect positive partner effect of perceived social support from family caregivers on anxiety and depression in patients with early lung cancer; there is a direct or indirect negative partner effect of social support from family caregivers on anxiety and depression in patients with advanced lung cancer.

Conclusions

This study confirmed the dyadic interdependence between perceived social support, illness uncertainty, anxiety, and depression among lung cancer patients and family caregivers. Furthermore, studies on differences between different lung cancer stages may provide a theoretical basis for different dyadic supportive interventions based on lung cancer stages.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249. https://doi.org/10.3322/caac.21660CrossRefPubMed

Walker J, Magill N, Mulick A, Symeonides S, Gourley C, Toynbee M, van Niekerk M, Burke K, Quartagno M, Frost C, Sharpe M (2020) Different independent associations of depression and anxiety with survival in patients with cancer. J Psychosom Res 138:110218. https://doi.org/10.1016/j.jpsychores.2020.1102183CrossRefPubMedPubMedCentral

Sklenarova H, Krümpelmann A, Haun MW, Friederich HC, Huber J, Thomas M, Winkler EC, Herzog W, Hartmann M (2015) When do we need to care about the caregiver? Supportive care needs, anxiety, and depression among informal caregivers of patients with cancer and cancer survivors. Cancer 121:1513–1519. https://doi.org/10.1002/cncr.29223CrossRefPubMed

Zimet GD, Powell SS, Farley GK, Werkman S, Berkoff KA (1990) Psychometric characteristics of the multidimensional scale of perceived social support. J Pers Assess 55:610–617. https://doi.org/10.1080/00223891.1990.9674095CrossRefPubMed

Kelley DE, Kent EE, Litzelman K, Mollica MA, Rowland JH (2019) Dyadic associations between perceived social support and cancer patient and caregiver health: an actor-partner interdependence modeling approach. Psychooncology 28:1453–1460. https://doi.org/10.1002/pon.5096CrossRefPubMedPubMedCentral

Jiang L, Zhang A, Wang M, Yang L, Ma L (2022) Perceived social support and distress in carers of people with lung cancer: the serial mediation of resilience and positive aspects of caregiving. Eur J Oncol Nurs 56:102084. https://doi.org/10.1016/j.ejon.2021.102084CrossRefPubMed

Hu T, Xiao J, Peng J, Kuang X, He B (2018) Relationship between resilience, social support as well as anxiety/depression of lung cancer patients: a cross-sectional observation study. J Cancer Res Ther 14:72–77. https://doi.org/10.4103/jcrt.JCRT_849_17CrossRefPubMed

Rapelli G, Donato S, Pagani AF, Parise M, Iafrate R, Pietrabissa G, Giusti EM, Castelnuovo G, Bertoni A (2021) The association between cardiac illness-related distress and partner support: the moderating role of dyadic coping. Front Psychol 12:624095. https://doi.org/10.3389/fpsyg.2021.624095CrossRefPubMedPubMedCentral

Rogers AH, Farris SG (2022) A meta-analysis of the associations of elements of the fear-avoidance model of chronic pain with negative affect, depression, anxiety, pain-related disability and pain intensity. Eur J Pain 26:1611–1635. https://doi.org/10.1002/ejp.1994CrossRefPubMedPubMedCentral

10.

Price RB, Duman R (2020) Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model. Mol Psychiatry 25:530–543. https://doi.org/10.1038/s41380-019-0615-xCrossRefPubMed

11.

Cheng J, Yang D, Zuo Q, Peng W, Zhu L, Jiang X (2022) Correlations between uncertainty in illness and anxiety, depression and quality of life in patients receiving maintenance haemodialysis: A cross-sectional study. Nurs Open 9:1322–1331. https://doi.org/10.1002/nop2.1177CrossRefPubMedPubMedCentral

12.

Mishel MH (1988) Uncertainty in illness. Image J Nurs Sch 20:225–232CrossRefPubMed

13.

Mishel MH (1990) Reconceptualization of the uncertainty in illness theory. Image J Nurs Sch 22:256–262. https://doi.org/10.1111/j.1547-5069.1990.tb00225.xCrossRefPubMed

14.

Sajjadi M, Rassouli M, Bahri N, Mohammadipoor F (2015) The correlation between perceived social support and illness uncertainty in people with human immunodeficiency virus/acquired immune deficiency syndrome in iran. Indian J Palliat Care 21:231–235. https://doi.org/10.4103/0973-1075.156508CrossRefPubMedPubMedCentral

15.

Sasai T, Onishi C (2017) Relationship between uncertainty and emotions in advanced lung cancer patients after initial therapy. J Med Invest 64:96–100. https://doi.org/10.2152/jmi.64.96CrossRefPubMed

16.

Yu Z, Sun D, Sun J (2022) Social support and fear of cancer recurrence among Chinese breast cancer survivors: the mediation role of illness uncertainty. Front Psychol 13:864129. https://doi.org/10.3389/fpsyg.2022.864129CrossRefPubMedCentral

17.

Sun D, Mao Z, Zhang X, Li J, Zhang L (2022) Relationship between post-traumatic stress symptoms and anticipatory grief in family caregivers of patients with advanced lung cancer: the mediation role of illness uncertainty. Front Psychiatry 13:914862. https://doi.org/10.3389/fpsyt.2022.914862CrossRefPubMedPubMedCentral

18.

Kelley HH (1983) The situational origins of human tendencies: a further reason for the formal analysis of structures. Pers Soc Psychol Bull 9:8–36CrossRef

19.

Olsen JA, Kenny DA (2006) Structural equation modeling with interchangeable dyads. Psychol Methods 11:127–141. https://doi.org/10.1037/1082-989X.11.2.12720CrossRefPubMed

20.

Suo R, Zhang L, Tao H, Ye F, Zhang Y, Yan J (2021) The effects of dyadic coping and marital satisfaction on posttraumatic growth among breast cancer couples. Support Care Cancer 29:5425–5433. https://doi.org/10.1007/s00520-021-06121-zCrossRefPubMed

21.

Varner S, Lloyd G, Ranby KW, Callan S, Robertson C, Lipkus IM (2019) Illness uncertainty, partner support, and quality of life: a dyadic longitudinal investigation of couples facing prostate cancer. Psychooncology 28:2188–2194. https://doi.org/10.1002/pon.5205CrossRefPubMed

22.

Lin Y, Luo X, Li J, Xu Y, Li Q (2021) The dyadic relationship of benefit finding and its impact on quality of life in colorectal cancer survivor and spousal caregiver couples. Support Care Cancer 29:1477–1486. https://doi.org/10.1007/s00520-020-05602-xCrossRefPubMed

23.

Yan Z, Zhang Q, Chang L, Liu Y, Li Y (2021) Dyadic effects of family resilience on post-traumatic stress symptoms among breast cancer patients and their primary family caregivers: a cross-sectional study. Eur J Oncol Nurs 53:101998. https://doi.org/10.1016/j.ejon.2021.101998CrossRefPubMed

24.

Wang H, Yue H, Ren M, Feng D (2021) Dyadic effects of family-functioning and resilience on quality of life in advanced lung cancer patients and caregivers: an actor-partner interdependence mediation model. Eur J Oncol Nurs 52:101963. https://doi.org/10.1016/j.ejon.2021.101963CrossRefPubMed

25.

Chen JJ, Wang QL, Li HP, Zhang T, Zhang SS, Zhou MK (2021) Family resilience, perceived social support, and individual resilience in cancer couples: analysis using the actor-partner interdependence mediation model. Eur J Oncol Nurs 52:101932. https://doi.org/10.1016/j.ejon.2021.101932CrossRefPubMed

26.

Zhang Y, Mohile S, Culakova E, Norton S, Loh KP, Kadambi S, Kehoe L, Aarne GV, Vogel VG, Burnette BL, Bradley TP, Flannery M (2022) The shared uncertainty experience of older adults with advanced cancer and their caregivers. Psychooncology 31:1041–1049. https://doi.org/10.1002/pon.5895CrossRefPubMedPubMedCentral

27.

Reale ML, Di MM (2020) Quality of life in patients with lung cancer: the way forward. Lancet Oncol 21:617–619. https://doi.org/10.1016/S1470-2045(20)30151-0CrossRefPubMed

28.

Zeng H, Chen W, Zheng R et al (2018) (2018) Changing cancer survival in China during 2003–15: a pooled analysis of 17 population-based cancer registries. Lancet Glob Health 6:e555–e567. https://doi.org/10.1016/S2214-109X(18)30127-XCrossRefPubMed

29.

Chen J, Zhu J, Jian H, Zhao Y, He S, He Y (2022) Typology of family relationships, psychological distress, and quality of life in chinese patients with advanced lung cancer: a latent profile analysis. Cancer Nurs 45:E655–E662. https://doi.org/10.1097/NCC.0000000000000968CrossRefPubMed

30.

Ye ZJ, She Y, Ling MZ et al (2018) Revised Chinese version of Mishel uncertainty in illness scale:development, reliability and validity. Chinese Gen Pract 21:1091–1097

31.

Wenyin W (2012) Study of the development of a Chinese version of Mishel uncertainty in illness scale-family member form and its application in family members of CCU patients (Master Thesis). Tianjin Medical University, Tianjin

32.

Li Q, Lin Y, Hu C, Xu Y, Zhou H, Yang L, Xu Y (2016) The Chinese version of hospital anxiety and depression scale: psychometric properties in Chinese cancer patients and their family caregivers. Eur J Oncol Nurs 25:16–23. https://doi.org/10.1016/j.ejon.2016.09.004CrossRefPubMed

33.

Ledermann T, Macho S, Kenny DA (2011) Assessing mediation in dyadic data using the actor-partner interdependence model. Struct Equ Modeling Multidisciplinary J 18:595–612. https://doi.org/10.1080/10705511.2011.607099CrossRef

34.

Cook WL, Kenny DA (2005) The actor–partner interdependence model: a model of bidirectional effects in developmental studies. Int J Behav Dev 29:101–109CrossRef

35.

Borges EL, Franceschini J, Costa LH, Fernandes AL, Jamnik S, Santoro IL (2017) Family caregiver burden: the burden of caring for lung cancer patients according to the cancer stage and patient quality of life. J Bras Pneumol 43:18–23. https://doi.org/10.1590/S1806-37562016000000177CrossRefPubMed

36.

Li J, Sun D, Zhang X, Zhao L, Zhang Y, Wang H, Ni N, Jiang G (2022) The relationship between anticipatory grief and illness uncertainty among Chinese family caregivers of patients with advanced lung cancer: a cross-sectional study. BMC Palliat Care 21:30. https://doi.org/10.1186/s12904-022-00925-4CrossRefPubMedPubMedCentral

37.

Kurita K, Garon EB, Stanton AL, Meyerowitz BE (2013) Uncertainty and psychological adjustment in patients with lung cancer. Psychooncology 22:1396–1401. https://doi.org/10.1002/pon.3155CrossRefPubMed

38.

Rajaei A (2022) The impact of pandemic on couples with cancer: examining the role of cancer-related communication on cancer-related distress via the actor-partner interdependence model. Fam J Alex Va 30:191–199. https://doi.org/10.1177/10664807211009803CrossRefPubMedPubMedCentral

39.

Dionne-Odom JN, Azuero A, Lyons KD, Hull JG, Tosteson T, Li Z, Li Z, Frost J, Dragnev KH, Akyar I, Hegel MT, Bakitas MA (2015) Benefits of early versus delayed palliative care to informal family caregivers of patients with advanced cancer: outcomes from the ENABLE III randomized controlled trial. J Clin Oncol 33:1446–1452. https://doi.org/10.1200/JCO.2014.58.7824CrossRefPubMed

Titel: Dyadic effects of social support, illness uncertainty on anxiety and depression among lung cancer patients and their caregivers: a cross-sectional study
verfasst von: Tian Wang
Jiaojiao Sun
Danfeng Gu
Siwen Shen
Yunxu Zhou
Zhiqiang Wang
Publikationsdatum: 01.07.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 7/2023
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-023-07876-3

Springer Medizin

Dyadic effects of social support, illness uncertainty on anxiety and depression among lung cancer patients and their caregivers: a cross-sectional study

Abstract

Objectives

Methods

Results

Conclusions

Neu im Fachgebiet Onkologie

Erhöhte Mortalität bei postpartalem Brustkrebs

Hypertherme Chemotherapie bietet Chance auf Blasenerhalt

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

Bessere Prognose mit links- statt rechtsseitigem Kolon-Ca.

Update Onkologie

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 7/2023

Perceived injustice and its impact on psychological distress in cancer patients and survivors

The impact of survivorship care plans on adolescent and young adult head and neck cancer survivors and their primary care providers

Effects of CALM intervention on neutrophil-to-lymphocyte ratio (NLR), fear of cancer recurrence and quality of life in patients with lung cancer

‘It’s communication between people who are going through the same thing’: experiences of informal interactions in hospital cancer treatment settings

Exploring pain among young people who have completed treatment for acute lymphoblastic leukemia: experiences of youth and caregivers

Assessment tools for patient-reported outcomes in multiple myeloma

Neu im Fachgebiet Onkologie

Erhöhte Mortalität bei postpartalem Brustkrebs

Hypertherme Chemotherapie bietet Chance auf Blasenerhalt

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

Bessere Prognose mit links- statt rechtsseitigem Kolon-Ca.

Update Onkologie