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Annals of Nuclear Medicine

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01.11.2012 | Original article

Effects of coverage extent and slice skipping on mean and maximum arterial ¹⁸F-FDG uptake ratios in patients with carotid plaque

verfasst von: Tae-Soo Noh, Jang Yoo, Se Won Kim, Eun Jeong Lee, Joon Young Choi, Byung-Tae Kim, Kyung-Han Lee

Erschienen in: Annals of Nuclear Medicine | Ausgabe 9/2012

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Abstract

Purpose

To investigate the effects of variable measurement methods on mean and maximum SUV ratios of ¹⁸F-FDG uptake in carotid arteries.

Methods

¹⁸F-FDG PET/CT images of 74 subjects with carotid plaque were analyzed for mean and maximum target-to-background ratio (TBR) of uptake. Agreement was analyzed between TBR scores obtained using different vessel coverage and slice skipping.

Results

Mean TBR was increased by extending coverage from common carotid artery (CCA; 1.25) to carotid artery (CA; 1.33) and inclusion of ascending aorta (CA/AA; 1.34). Maximum TBR was increased from 1.47 to 1.54 and 1.61 by respective extensions. Both mean and maximum TBR were closely correlated between vessels. ICC and Kappa statistics revealed near perfect agreement between TBR obtained using every 2 or 3 segments and that without sipping. Bland–Altman plots showed bias by slice skipping to remain small, particularly for mean TBR. Finally, high correlations were displayed between mean and maximum TBR.

Conclusions

Analysis of mean and maximum arterial ¹⁸F-FDG uptake in patients with carotid plaque is likely to benefit from extending coverage to segments above and below the CCA. The extra burden of measurement, in turn, can be lightened by skipping up to every 2 of 3 slices without compromising accuracy of results.

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Titel: Effects of coverage extent and slice skipping on mean and maximum arterial 18F-FDG uptake ratios in patients with carotid plaque
verfasst von: Tae-Soo Noh
Jang Yoo
Se Won Kim
Eun Jeong Lee
Joon Young Choi
Byung-Tae Kim
Kyung-Han Lee
Publikationsdatum: 01.11.2012
Verlag: Springer Japan
Erschienen in: Annals of Nuclear Medicine / Ausgabe 9/2012
Print ISSN: 0914-7187
Elektronische ISSN: 1864-6433
DOI: https://doi.org/10.1007/s12149-012-0633-0

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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