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Sleep and Breathing

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13.04.2022 | Sleep Breathing Physiology and Disorders • Review

Effects of different sleep disorders on frailty in the elderly: a systematic review and meta-analysis of observational studies

verfasst von: Ruijia Sun, Yongqiu Xie, Wen Jiang, E. Wang, Xingli Li

Erschienen in: Sleep and Breathing | Ausgabe 1/2023

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Abstract

Study objectives

Frailty is frequently reported following sleep disorders; however, the extent to which sleep disorders influence frailty remains unclear. In the current study, we performed a meta-analysis to evaluate the quantitative effects of different sleep disorders on frailty in the elderly.

Methods

We conducted a systematic search of several databases, including PubMed, Web of Science, Embase, and Scopus, to retrieve articles published from May 2009 to June 2021. The data outcomes are expressed as the odds ratio (OR) and 95% confidence interval (CI).

Results

Eighteen studies were included, with 39669 participants. Older adults with sleep disorders were found to have a higher risk of frailty (pooled OR = 1.49, 95%CI = 1.35–1.64, p < 0.01). Specifically, daytime sleepiness (pooled OR = 1.69, 95%CI = 1.09–2.61, p < 0.01), short sleep duration (pooled OR = 1.36, 95%CI = 1.20–1.54, p = 0.45), long sleep duration (pooled OR = 1.99, 95%CI = 1.39–2.85, p = 0.02), sleep latency extension (pooled OR = 1.38, 95%CI = 1.19–1.60, p = 0.72), and sleep disordered breathing (pooled OR = 1.30, 95%CI = 1.11–1.53, p = 0.37) were correlated with frailty.

Conclusions

The risk of frailty differs between older adults with sleep disorders and controls, suggesting that the relationships between different sleep disorders and frailty vary. These results highlight the need to monitor sleep disorders of the elderly and conduct intervention to prevent or delay the frailty process.

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Titel: Effects of different sleep disorders on frailty in the elderly: a systematic review and meta-analysis of observational studies
verfasst von: Ruijia Sun
Yongqiu Xie
Wen Jiang
E. Wang
Xingli Li
Publikationsdatum: 13.04.2022
Verlag: Springer International Publishing
Erschienen in: Sleep and Breathing / Ausgabe 1/2023
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-022-02610-5

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Abstract

Study objectives

Methods

Results

Conclusions

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