nach oben

Erschienen in:

02.02.2023 | Review

Environmental factors affecting pregnancy outcomes

verfasst von: Anastasia-Konstantina Sakali, Maria Papagianni, Alexandra Bargiota, Aleksandra Rasic-Markovic, Djuro Macut, George Mastorakos

Erschienen in: Endocrine | Ausgabe 3/2023

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Pregnancy represents a fragile period in the life of a woman, vulnerable to hazardous environmental substances which might affect maternal and fetal metabolism. The possible influence of environmental factors, including endocrine disrupting chemicals (EDCs), upon the mother and the fetus before and/or during pregnancy might be associated directly and/or indirectly to deleterious pregnancy outcomes. Because the existence of such associations would be, to our view, of major importance to the scientific community, their investigation is the scope of this critical review.

Methods

This critical review includes in vivo animal and human studies regarding the role of environmental factors, including EDCs, on pregnancy outcomes complying with the SANRA (a scale for the quality assessment of narrative review articles) questions for narrative reviews. Studies were identified by searching the MEDLINE (PubMed and PubMed Central), the Cochrane library and the Google Scholar databases till October 2022 with the combinations of the appropriate key words (detailed environmental factors including EDCs AND detailed negative pregnancy outcomes) as well as by scanning references from already included articles and relevant reviews manually. Because environmental factors and EDCs have been associated to epigenetic alterations, special care has been given to EDC-induced transgenerational effects on pregnancy outcomes.

Results

The existing evidence suggests positive associations between specific environmental factors and negative pregnancy outcomes such as ectopic pregnancies, pregnancy losses, gestational diabetes, hypertensive disorders of pregnancy, preterm births, birth defects, intrauterine growth restriction, and small or large for gestational age babies.

Conclusion

Environmental factors and EDCs may have a catalytic effect on the course and the outcomes of pregnancy.

Organization, W.H.: International classification of functioning, disability and health: ICF. World Health Organization (2001)

Safety, I.P. on C.: Global assessment on the state of the science of endocrine disruptors. (2002)

L.C. Chappell, P.T. Seed, J.Myers, R.S.Taylor, L.C. Kenny, G.A. Dekker, J.J. Walker, L.M.E. McCowan, R.A.North, L. Poston. Exploration and confirmation of factors associated with uncomplicated pregnancy in nulliparous women: prospective cohort study. BMJ. 347, (2013). https://doi.org/10.1136/bmj.f6398

A.J. Gaskins, S.A. Missmer, J.W. Rich-Edwards, P.L. Williams, I. Souter, J.E. Chavarro, Demographic, lifestyle, and reproductive risk factors for ectopic pregnancy. Fertil. Steril. 110, 1328–1337 (2018). https://doi.org/10.1016/j.fertnstert.2018.08.022CrossRefPubMedPubMedCentral

R.N. Hoover, M. Hyer, R.M Pfeiffer, E. Adam, B. Bond, A.L Cheville, T. Colton, P. Hartge, E.E Hatch, A.L Herbst, B.Y. Karlan, R. Kaufman, K.L Noller, J.R Palmer, S.J. Robboy, R.C. Saal, W. Strohsnitter, L. Titus-Ernstoff, R.Troisi. Adverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol, https://www.nejm.org/doi/10.1056/NEJMoa1013961?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov

T. Xue, T. Zhu, G. Geng, Q. Zhang, Association between pregnancy loss and ambient PM2·5 using survey data in Africa: a longitudinal case-control study, 1998–2016. Lancet Planet. Health. 3, e219–ee225 (2019). https://doi.org/10.1016/S2542-5196(19)30047-6CrossRefPubMed

Practice Committee of the American Society for Reproductive Medicine: Obesity and reproduction: a committee opinion. Fertil. Steril. 104, 1116–1126 (2015). https://doi.org/10.1016/j.fertnstert.2015.08.018

J.M. Campbell, M. Lane, J.A. Owens, H.W. Bakos, Paternal obesity negatively affects male fertility and assisted reproduction outcomes: a systematic review and meta-analysis. Reprod. BioMedicine Online. 31, 593–604 (2015). https://doi.org/10.1016/j.rbmo.2015.07.012CrossRef

G. Sebastiani, V. Andreu-Fernández, A. Herranz Barbero, V. Aldecoa-Bilbao, X. Miracle, E. Meler Barrabes, A. Balada Ibañez, M. Astals-Vizcaino, S. Ferrero-Martínez, M.D. Gómez-Roig, O. García-Algar, Eating Disorders During Gestation: Implications for Mother’s Health, Fetal Outcomes, and Epigenetic Changes. Front. Pediatrics. 8, 587 (2020). https://doi.org/10.3389/fped.2020.00587CrossRef

10.

J. Li, H. Zhao, J.-M. Song, J. Zhang, Y.-L. Tang, C.-M. Xin, A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy. Int. J. Gynecol. Obstet. 130, 116–122 (2015). https://doi.org/10.1016/j.ijgo.2015.03.033CrossRef

11.

J.B. Dagher, C.K. Hahn-Townsend, A. Kaimal, M.A. Mansi, J.E. Henriquez, D.G. Tran, C.R. Laurent, C.J. Bacak, H.E. Buechter, C. Cambric, J. Spivey, Y.-J. Chuang, E.J. Campbell, A. Mandal, P.S. Mohankumar, S.M.J. MohanKumar, Independent and combined effects of Bisphenol A and Diethylhexyl Phthalate on gestational outcomes and offspring development in Sprague-Dawley rats. Chemosphere 263, 128307 (2021). https://doi.org/10.1016/j.chemosphere.2020.128307CrossRefPubMed

12.

C. Messerlian, I. Souter, A.J. Gaskins, P.L. Williams, J.B. Ford, Y.-H. Chiu, A.M. Calafat, R. Hauser, for the Earth Study Team: Urinary phthalate metabolites and ovarian reserve among women seeking infertility care. Hum. Reprod. 31, 75–83 (2016). https://doi.org/10.1093/humrep/dev292CrossRefPubMed

13.

R. Quansah, F.A. Armah, D.K. Essumang, I. Luginaah, E. Clarke, K. Marfoh, S.J. Cobbina, E. Nketiah-Amponsah, P.B. Namujju, S. Obiri, M. Dzodzomenyo, Association of Arsenic with Adverse Pregnancy Outcomes/Infant Mortality: A Systematic Review and Meta-Analysis. Environ. Health Perspect. 123, 412–421 (2015). https://doi.org/10.1289/ehp.1307894CrossRefPubMedPubMedCentral

14.

X. Wang, X. Chen, X. Feng, F. Chang, M. Chen, Y. Xia, L. Chen. Triclosan causes spontaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice. Sci Rep. 5, (2015). https://doi.org/10.1038/srep18252

15.

A. Conforti, M. Mascia, G. Cioffi, C. De Angelis, G. Coppola, P. De Rosa, R. Pivonello, C. Alviggi, G. De Placido, Air pollution and female fertility: a systematic review of literature. Reprod. Biol. Endocrinol. 16, 117 (2018). https://doi.org/10.1186/s12958-018-0433-zCrossRefPubMedPubMedCentral

16.

M.B. Cavalcante, M. Sarno, A.B. Peixoto, E.A. Júnior, R. Barini, Obesity and recurrent miscarriage: A systematic review and meta-analysis. J. Obstet. Gynaecol. Res. 45, 30–38 (2019). https://doi.org/10.1111/jog.13799CrossRefPubMed

17.

L.M. Begtrup, I.O. Specht, P.E.C. Hammer, E.M. Flachs, A.H. Garde, J. Hansen, Å.M. Hansen, H.A. Kolstad, A.D. Larsen, J.P. Bonde, Night work and miscarriage: a Danish nationwide register-based cohort study. Occup. Environ. Med. 76, 302–308 (2019). https://doi.org/10.1136/oemed-2018-105592CrossRefPubMed

18.

H. Klonoff-Cohen, P. Lam-Kruglick, C. Gonzalez, Effects of maternal and paternal alcohol consumption on the success rates of in vitro fertilization and gamete intrafallopian transfer. Fertil. Steril. 79, 330–339 (2003). https://doi.org/10.1016/S0015-0282(02)04582-XCrossRefPubMed

19.

B.L. Pineles, E. Park, J.M. Samet, Systematic Review and Meta-Analysis of Miscarriage and Maternal Exposure to Tobacco Smoke During Pregnancy. Am. J. Epidemiol. 179, 807–823 (2014). https://doi.org/10.1093/aje/kwt334CrossRefPubMedPubMedCentral

20.

M. Sugiura-Ogasawara, Y. Ozaki, S. Sonta, T. Makino, K. Suzumori, Exposure to bisphenol A is associated with recurrent miscarriage. Hum. Reprod. 20, 2325–2329 (2005). https://doi.org/10.1093/humrep/deh888CrossRefPubMed

21.

R.B. Lathi, C.A. Liebert, K.F. Brookfield, J.A. Taylor, F.S. vom Saal, V.Y. Fujimoto, V.L. Baker, Conjugated bisphenol A in maternal serum in relation to miscarriage risk. Fertil. Steril. 102, 123–128 (2014). https://doi.org/10.1016/j.fertnstert.2014.03.024CrossRefPubMedPubMedCentral

22.

D. Caserta, A. Mantovani, R. Marci, A. Fazi, F. Ciardo, C. La Rocca, F. Maranghi, M. Moscarini, Environment and women’s reproductive health. Hum. Reprod. Update. 17, 418–433 (2011). https://doi.org/10.1093/humupd/dmq061CrossRefPubMed

23.

S. Ha, D. Liu, Y. Zhu, S. Soo Kim, S. Sherman, K.L. Grantz, P. Mendola. Ambient Temperature and Stillbirth: A Multi-Center Retrospective Cohort Study. Environ Health Perspect. 125, (2017). https://doi.org/10.1289/EHP945.

24.

D. Aune, O.D. Saugstad, T. Henriksen, S. Tonstad, Maternal Body Mass Index and the Risk of Fetal Death, Stillbirth, and Infant Death: A Systematic Review and Meta-analysis. JAMA 311, 1536–1546 (2014). https://doi.org/10.1001/jama.2014.2269CrossRefPubMed

25.

R.M. Srinivasjois, S. Shah, P.S. Shah, Biracial couples and adverse birth outcomes: a systematic review and meta-analyses. Acta Obstetricia et. Gynecologica Scandinavica. 91, 1134–1146 (2012). https://doi.org/10.1111/j.1600-0412.2012.01501.xCrossRefPubMed

26.

S.A. Lorch, E. Enlow, The role of social determinants in explaining racial/ethnic disparities in perinatal outcomes. Pediatr. Res. 79, 141–147 (2016). https://doi.org/10.1038/pr.2015.199CrossRefPubMed

27.

Y. Yu, A. Yang, J. Zhang, S. Hu, Maternal exposure to the mixture of organophosphorus pesticides induces reproductive dysfunction in the offspring. Environ. Toxicol. 28, 507–515 (2013). https://doi.org/10.1002/tox.20741CrossRefPubMed

28.

W. Bai, Y. Li, Y. Niu, Y. Ding, X. Yu, B. Zhu, R. Duan, H. Duan, C. Kou, Y. Li, Z. Sun, Association between ambient air pollution and pregnancy complications: A systematic review and meta-analysis of cohort studies. Environ. Res. 185, 109471 (2020). https://doi.org/10.1016/j.envres.2020.109471CrossRefPubMed

29.

F. Amati, S. Hassounah, A. Swaka, The Impact of Mediterranean Dietary Patterns During Pregnancy on Maternal and Offspring Health. Nutrients 11, 1098 (2019). https://doi.org/10.3390/nu11051098CrossRefPubMedPubMedCentral

30.

G. Valsamakis, E.L. Kyriazi, Z. Mouslech, C. Siristatidis, G. Mastorakos, Effect of maternal obesity on pregnancy outcomes and long-term metabolic consequences. Hormones 14, 345–357 (2015). https://doi.org/10.14310/horm.2002.1590CrossRefPubMed

31.

R.M. Shaffer, K.K. Ferguson, L. Sheppard, T. James-Todd, S. Butts, S. Chandrasekaran, S.H. Swan, E.S. Barrett, R. Nguyen, N. Bush, T.F. McElrath, S. Sathyanarayana, Maternal urinary phthalate metabolites in relation to gestational diabetes and glucose intolerance during pregnancy. Environ. Int. 123, 588–596 (2019). https://doi.org/10.1016/j.envint.2018.12.021CrossRefPubMedPubMedCentral

32.

G.D. Shapiro, L. Dodds, T.E. Arbuckle, J. Ashley-Martin, W. Fraser, M. Fisher, S. Taback, E. Keely, M.F. Bouchard, P. Monnier, R. Dallaire, A.S. Morisset, A.S. Ettinger, Exposure to phthalates, bisphenol A and metals in pregnancy and the association with impaired glucose tolerance and gestational diabetes mellitus: The MIREC study. Environ. Int. 83, 63–71 (2015). https://doi.org/10.1016/j.envint.2015.05.016CrossRefPubMed

33.

A.J. Beltran, J. Wu, O. Laurent, Associations of Meteorology with Adverse Pregnancy Outcomes: A Systematic Review of Preeclampsia, Preterm Birth and Birth Weight. Int. J. Environ. Res. Pub. Health. 11, 91–172 (2014). https://doi.org/10.3390/ijerph110100091CrossRef

34.

F. Leclerc, M.-F. Dubois, A. Aris, Maternal, placental and fetal exposure to bisphenol A in women with and without preeclampsia. Hypertension Pregnancy. 33, 341–348 (2014). https://doi.org/10.3109/10641955.2014.892607CrossRef

35.

X. Ye, W. Pan, Y. Zhao, S. Zhao, Y. Zhu, W. Liu, J. Liu, Association of pyrethroids exposure with onset of puberty in Chinese girls. Environ. Pollut. 227, 606–612 (2017). https://doi.org/10.1016/j.envpol.2017.04.035CrossRefPubMed

36.

E. Cantonwine David, D. Meeker John, K. Ferguson Kelly, B. Mukherjee, R. Hauser, T.F. McElrath, Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia. Environ. Health Perspect. 124, 1651–1655 (2016). https://doi.org/10.1289/EHP188CrossRefPubMedPubMedCentral

37.

E.F. Werner, J.M. Braun, K. Yolton, J.C. Khoury, B.P. Lanphear, The association between maternal urinary phthalate concentrations and blood pressure in pregnancy: The HOME Study. Environ. Health. 14, 75 (2015). https://doi.org/10.1186/s12940-015-0062-3CrossRefPubMedPubMedCentral

38.

X. Han, J. Li, Y. Wang, S. Xu, Y. Li, H. Liu, Y. Zhou, H. Zhao, J. Fang, Z. Cai, W. Xia, Association between phthalate exposure and blood pressure during pregnancy. Ecotoxicol. Environ. Saf. 189, 109944 (2020). https://doi.org/10.1016/j.ecoenv.2019.109944CrossRefPubMed

39.

A. El-Badry, M. Rezk, H. El-Sayed, Mercury-induced Oxidative Stress May Adversely Affect Pregnancy Outcome among Dental Staff: A Cohort Study. Int J. Occup. Environ. Med. (IJOEM) 9, 113–1189 (2018). https://doi.org/10.15171/ijoem.2018.1181CrossRefPubMed

40.

M. Vigeh, K. Yokoyama, F. Ramezanzadeh, M. Dahaghin, T. Sakai, Y. Morita, F. Kitamura, H. Sato, Y. Kobayashi, Lead and other trace metals in preeclampsia: A case–control study in Tehran, Iran. Environ. Res. 100, 268–275 (2006). https://doi.org/10.1016/j.envres.2005.05.005CrossRefPubMed

41.

E.M. Rosen, M.I. Muñoz, T. McElrath, D.E. Cantonwine, K.K. Ferguson, Environmental contaminants and preeclampsia: A systematic literature review. J. Toxicol. Environ. Health B Crit. Rev. 21, 291–319 (2018). https://doi.org/10.1080/10937404.2018.1554515CrossRefPubMedPubMedCentral

42.

L.G. Kahn, L. Trasande, Environmental Toxicant Exposure and Hypertensive Disorders of Pregnancy: Recent Findings. Curr. Hypertens. Rep. 20, 87 (2018). https://doi.org/10.1007/s11906-018-0888-5CrossRefPubMedPubMedCentral

43.

A.E. Poropat, M.A.S. Laidlaw, B. Lanphear, A. Ball, H.W. Mielke, Blood lead and preeclampsia: A meta-analysis and review of implications. Environ. Res. 160, 12–19 (2018). https://doi.org/10.1016/j.envres.2017.09.014CrossRefPubMed

44.

R.M. Toichuev, L.V. Zhilova, T.R. Paizildaev, M.S. Khametova, A. Rakhmatillaev, K.S. Sakibaev, Z.A. Madykova, A.U. Toichueva, M. Schlumpf, R. Weber, W. Lichtensteiger, Organochlorine pesticides in placenta in Kyrgyzstan and the effect on pregnancy, childbirth, and newborn health. Environ. Sci. Pollut. Res. 25, 31885–31894 (2018). https://doi.org/10.1007/s11356-017-0962-6CrossRef

45.

M.M. Smarr, K.L. Grantz, C. Zhang, R. Sundaram, J.M. Maisog, D.B. Barr, G.M.B. Louis, Persistent organic pollutants and pregnancy complications. Sci. Total Environ. 551–552, 285–291 (2016). https://doi.org/10.1016/j.scitotenv.2016.02.030CrossRefPubMed

46.

J. Murray, B. Eskenazi, R. Bornman, F.W. Gaspar, M. Crause, M. Obida, J. Chevrier, Exposure to DDT and hypertensive disorders of pregnancy among South African women from an indoor residual spraying region: The VHEMBE study. Environ. Res. 162, 49–54 (2018). https://doi.org/10.1016/j.envres.2017.12.006CrossRefPubMed

47.

S. Sun, K.R. Weinberger, K.R. Spangler, M.N. Eliot, J.M. Braun, G.A. Wellenius, Ambient temperature and preterm birth: A retrospective study of 32 million US singleton births. Environ. Int. 126, 7–13 (2019). https://doi.org/10.1016/j.envint.2019.02.023CrossRefPubMedPubMedCentral

48.

T. Guo, Y. Wang, H. Zhang, Y. Zhang, J. Zhao, Y. Wang, X. Xie, L. Wang, Q. Zhang, D. Liu, Y. He, Y. Yang, J. Xu, Z. Peng, X. Ma, The association between ambient temperature and the risk of preterm birth in China. Sci. Total Environ. 613–614, 439–446 (2018). https://doi.org/10.1016/j.scitotenv.2017.09.104CrossRefPubMed

49.

S.J. Lee, S. Hajat, P.J. Steer, V. Filippi, A time-series analysis of any short-term effects of meteorological and air pollution factors on preterm births in London, UK. Environ. Res. 106, 185–194 (2008). https://doi.org/10.1016/j.envres.2007.10.003CrossRefPubMed

50.

J.-R. He, Y. Liu, X.-Y. Xia, W.-J. Ma, H.-L. Lin, H.-D. Kan, J.-H. Lu, Q. Feng, W.-J. Mo, P. Wang, H.-M. Xia, X. Qiu, L.J. Muglia,, Ambient Temperature and the Risk of Preterm Birth in Guangzhou, China (2001-2011). Environ Health Perspect. 124, 1100–1106 (2016)CrossRefPubMed

51.

P. Dadvand, X. Basagaña, C. Sartini, F. Figueras, M. Vrijheid, A. de Nazelle, J. Sunyer, M.J. Nieuwenhuijsen, Climate Extremes and the Length of Gestation. Environ. Health Perspect. 119, 1449–1453 (2011). https://doi.org/10.1289/ehp.1003241CrossRefPubMedPubMedCentral

52.

C. Liu, J. Sun, Y. Liu, H. Liang, M. Wang, C. Wang, T. Shi, Different exposure levels of fine particulate matter and preterm birth: a meta-analysis based on cohort studies. Environ. Sci. Pollut. Res Int. 24, 17976–17984 (2017). https://doi.org/10.1007/s11356-017-9363-0CrossRefPubMed

53.

R.F. Goldstein, S.K. Abell, S. Ranasinha, M. Misso, J.A. Boyle, M.H. Black, N. Li, G. Hu, F. Corrado, L. Rode, Y.J. Kim, M. Haugen, W.O. Song, M.H. Kim, A. Bogaerts, R. Devlieger, J.H. Chung, H.J. Teede, Association of Gestational Weight Gain With Maternal and Infant Outcomes: A Systematic Review and Meta-analysis. JAMA 317, 2207–2225 (2017). https://doi.org/10.1001/jama.2017.3635CrossRefPubMedPubMedCentral

54.

B. Liu, G. Xu, Y. Sun, Y. Du, R. Gao, L.G. Snetselaar, M.K. Santillan, W. Bao, Association between maternal pre-pregnancy obesity and preterm birth according to maternal age and race or ethnicity: a population-based study. Lancet Diabetes Endocrinol. 7, 707–714 (2019). https://doi.org/10.1016/S2213-8587(19)30193-7CrossRefPubMedPubMedCentral

55.

C. Trumpff, G. Sturm, M. Picard, S. Foss, S. Lee, T. Feng, A. Cardenas, C. McCormack, F.A. Champagne, C. Monk, Added sugar intake during pregnancy: Fetal behavior, birth outcomes, and placental DNA methylation. Developmental Psychobiol. 63, 878–889 (2021). https://doi.org/10.1002/dev.22088CrossRef

56.

M.G. Porpora, I. Piacenti, S. Scaramuzzino, L. Masciullo, F. Rech, P. Benedetti Panici, Environmental Contaminants Exposure and Preterm Birth: A Systematic Review. Toxics 7, 11 (2019). https://doi.org/10.3390/toxics7010011CrossRefPubMedPubMedCentral

57.

R.J. Baer, C.D. Chambers, K.K. Ryckman, S.P. Oltman, L. Rand, L.L. Jelliffe-Pawlowski, Risk of preterm and early term birth by maternal drug use. J. Perinatol. 39, 286–294 (2019). https://doi.org/10.1038/s41372-018-0299-0CrossRefPubMed

58.

A.D. Salow, L.R. Pool, W.A. Grobman, K.N. Kershaw, Associations of neighborhood-level racial residential segregation with adverse pregnancy outcomes. Am. J. Obstet. Gynecol. 218, 351.e1–351.e7 (2018). https://doi.org/10.1016/j.ajog.2018.01.022CrossRefPubMed

59.

K.A. de Oliveira, E.M. de Araújo, K.A. de Oliveira, C.A. Casotti, C.A.L. da Silva, D.B. dos Santos. Association between race/skin color and premature birth: a systematic review with meta-analysis. Rev Saude Publica. 52, (2018). https://doi.org/10.11606/S1518-8787.2018052000406

60.

D.E. Cantonwine, K.K. Ferguson, B. Mukherjee, T.F. McElrath, J.D. Meeker, Urinary Bisphenol A Levels during Pregnancy and Risk of Preterm Birth. Environ. Health Perspect. 123, 895–901 (2015). https://doi.org/10.1289/ehp.1408126CrossRefPubMedPubMedCentral

61.

A. Broe, A. Pottegård, J. Hallas, T.P. Ahern, R.F. Lamont, P. Damkier, Phthalate exposure from drugs during pregnancy and possible risk of preterm birth and small for gestational age. Eur. J. Obstet. Gynecol. Reprod. Biol. 240, 293–299 (2019). https://doi.org/10.1016/j.ejogrb.2019.07.023CrossRefPubMed

62.

G. Latini, C. De Felice, G. Presta, A. Del Vecchio, I. Paris, F. Ruggieri, P. Mazzeo, In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy. Environ. Health Perspect. 111, 1783–1785 (2003). https://doi.org/10.1289/ehp.6202CrossRefPubMedPubMedCentral

63.

S. Rattan, C. Zhou, C. Chiang, S. Mahalingam, E. Brehm, J.A. Flaws, Exposure to endocrine disruptors during adulthood: Consequences for female fertility. J. Endocrinol. 233, R109–R129 (2017). https://doi.org/10.1530/JOE-17-0023CrossRefPubMedPubMedCentral

64.

L.A. Geer, B.F.G. Pycke, J. Waxenbaum, D.M. Sherer, O. Abulafia, R.U. Halden, Association of birth outcomes with fetal exposure to parabens, triclosan and triclocarban in an immigrant population in Brooklyn, New York. J. Hazard. Mater. 323, 177–183 (2017). https://doi.org/10.1016/j.jhazmat.2016.03.028CrossRefPubMed

65.

Z. Deji, P. Liu, X. Wang, X. Zhang, Y. Luo, Z. Huang, Association between maternal exposure to perfluoroalkyl and polyfluoroalkyl substances and risks of adverse pregnancy outcomes: A systematic review and meta-analysis. Sci. Total Environ. 783, 146984 (2021). https://doi.org/10.1016/j.scitotenv.2021.146984CrossRefPubMed

66.

K.H. Al-Gubory, P.A. Fowler, C. Garrel, The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes. Int. J. Biochem. Cell Biol. 42, 1634–1650 (2010). https://doi.org/10.1016/j.biocel.2010.06.001CrossRefPubMed

67.

B. Wang, J.-J. Liu, Y. Wang, L. Fu, R. Shen, Z. Yu, H. Wang, Y.-H. Chen, C. Zhang, X.-H. Meng, D.-X. Xu, Maternal Fenvalerate Exposure Induces Fetal Intrauterine Growth Restriction Through Disrupting Placental Thyroid Hormone Receptor Signaling. Toxicol. Sci. 157, 377–386 (2017). https://doi.org/10.1093/toxsci/kfx052CrossRefPubMed

68.

P.E. Clayton, S. Cianfarani, P. Czernichow, G. Johannsson, R. Rapaport, A. Rogol, Management of the Child Born Small for Gestational Age through to Adulthood: A Consensus Statement of the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society. J. Clin. Endocrinol. Metab. 92, 804–810 (2007). https://doi.org/10.1210/jc.2006-2017CrossRefPubMed

69.

C. Iñiguez, A. Esplugues, J. Sunyer, M. Basterrechea, A. Fernández-Somoano, O. Costa, M. Estarlich, I. Aguilera, A. Lertxundi, A. Tardón, M. Guxens, M. Murcia, M.-J. Lopez-Espinosa, F. Ballester; null null, Prenatal Exposure to NO2 and Ultrasound Measures of Fetal Growth in the Spanish INMA Cohort. Environ. Health Perspect. 124, 235–242 (2016). https://doi.org/10.1289/ehp.1409423CrossRefPubMed

70.

A.A. Amoako, T.M. Nafee, B. Ola. Epigenetic Influences During the Periconception Period and Assisted Reproduction. Στο: Fazeli, A. και Holt, W.V. (επιμ.) Periconception in Physiology and Medicine. σσ. 15–39. Springer International Publishing, Cham (2017)

71.

S.L. Clay, M.J Woodson, R. Kersh. An Exploration of Socio-demographic, Economic, and Environmental Factors in Black/White Disparities in Low Birth Weight Outcomes: A Cross-Sectional Study. J Res. Health Sci. 21, (2021). https://doi.org/10.34172/jrhs.v0i0.6408

72.

A. Veiga-Lopez, K. Kannan, C. Liao, W. Ye, S.E. Domino, V. Padmanabhan, Gender-Specific Effects on Gestational Length and Birth Weight by Early Pregnancy BPA Exposure. J. Clin. Endocrinol. Metab. 100, E1394–E1403 (2015). https://doi.org/10.1210/jc.2015-1724CrossRefPubMedPubMedCentral

73.

C.-Y. Hu, F.-L. Li, X.-G. Hua, W. Jiang, C. Mao, X.-J. Zhang, The association between prenatal bisphenol A exposure and birth weight: a meta-analysis. Reprod. Toxicol. 79, 21–31 (2018). https://doi.org/10.1016/j.reprotox.2018.04.013CrossRefPubMed

74.

M. Casas, D. Valvi, A. Ballesteros-Gomez, M. Gascon, M.F. Fernández, R. Garcia-Esteban, C. Iñiguez, D. Martínez, M. Murcia, N. Monfort, N. Luque, S. Rubio, R. Ventura, J. Sunyer, M. Vrijheid, Exposure to Bisphenol A and Phthalates during Pregnancy and Ultrasound Measures of Fetal Growth in the INMA-Sabadell Cohort. Environ. Health Perspect. 124, 521–528 (2016). https://doi.org/10.1289/ehp.1409190CrossRefPubMed

75.

J. Fang, H. Liu, H. Zhao, M. Wong, S. Xu, Z. Cai, Association of prenatal exposure to organochlorine pesticides and birth size. Sci. Total Environ. 654, 678–683 (2019). https://doi.org/10.1016/j.scitotenv.2018.10.384CrossRefPubMed

76.

J. Chevrier, S. Rauch, M. Crause, M. Obida, F. Gaspar, R. Bornman, B. Eskenazi, Associations of Maternal Exposure to Dichlorodiphenyltrichloroethane and Pyrethroids With Birth Outcomes Among Participants in the Venda Health Examination of Mothers, Babies and Their Environment Residing in an Area Sprayed for Malaria Control. Am. J. Epidemiol. 188, 130–140 (2019). https://doi.org/10.1093/aje/kwy143CrossRefPubMed

77.

M.-J. Lopez-Espinosa, M. Murcia, C. Iñiguez, E. Vizcaino, O. Costa, A. Fernández-Somoano, M. Basterrechea, A. Lertxundi, M. Guxens, M. Gascon, F. Goñi-Irigoyen, J.O. Grimalt, A. Tardón, F. Ballester, Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain). Environ. Health Perspect. 124, 157–163 (2016). https://doi.org/10.1289/ehp.1408907CrossRefPubMed

78.

E. Papadopoulou, M. Kogevinas, M. Botsivali, M. Pedersen, H. Besselink, M.A. Mendez, S. Fleming, L.J. Hardie, L.E. Knudsen, J. Wright, S. Agramunt, J. Sunyer, B. Granum, K.B. Gutzkow, G. Brunborg, J. Alexander, H.M. Meltzer, A.L. Brantsæter, K. Sarri, L. Chatzi, D.F. Merlo, J.C. Kleinjans, M. Haugen, Maternal diet, prenatal exposure to dioxin-like compounds and birth outcomes in a European prospective mother–child study (NewGeneris). Sci. Total Environ. 484, 121–128 (2014). https://doi.org/10.1016/j.scitotenv.2014.03.047CrossRefPubMed

79.

A. Wesselink, M. Warner, S. Samuels, A. Parigi, P. Brambilla, P. Mocarelli, B. Eskenazi, Maternal dioxin exposure and pregnancy outcomes over 30 years of follow-up in Seveso. Environ. Int. 63, 143–148 (2014). https://doi.org/10.1016/j.envint.2013.11.005CrossRefPubMed

80.

P. Rossner, N. Tabashidze, M. Dostal, Z. Novakova, I. Chvatalova, M. Spatova, R.J. Sram, Genetic, Biochemical, and Environmental Factors Associated with Pregnancy Outcomes in Newborns from the Czech Republic. Environ. Health Perspect. 119, 265–271 (2011). https://doi.org/10.1289/ehp.1002470CrossRefPubMed

81.

R. Gaillard, B. Durmuş, A. Hofman, J.P. Mackenbach, E.A.P. Steegers, V.W.V. Jaddoe, Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy. Obesity 21, 1046–1055 (2013). https://doi.org/10.1002/oby.20088CrossRefPubMed

82.

H. Kyozuka, K. Fujimori, M. Hosoya, S. Yasumura, T. Yokoyama, A. Sato, K. Hashimoto, The Japan Environment and Children’s Study (JECS) in Fukushima Prefecture: Pregnancy Outcome after the Great East Japan Earthquake. Tohoku J. Exp. Med. 246, 27–33 (2018). https://doi.org/10.1620/tjem.246.27CrossRefPubMed

83.

K.J. Stothard, P.W.G. Tennant, R. Bell, J. Rankin, Maternal Overweight and Obesity and the Risk of Congenital Anomalies: A Systematic Review and Meta-analysis. JAMA 301, 636–650 (2009). https://doi.org/10.1001/jama.2009.113CrossRefPubMed

84.

S. Baldacci, F. Gorini, M. Santoro, A. Pierini, F. Minichilli, F. Bianchi, Environmental and individual exposure and the risk of congenital anomalies: a review of recent epidemiological evidence. Epidemiol. Prev. 42, 1–34 (2018). https://doi.org/10.19191/EP18.3-4.S1.P001.057CrossRefPubMed

85.

C. Yu, Y. Wei, X. Tang, B. Liu, L. Shen, C. Long, T. Lin, D. He, S. Wu, G. Wei, Maternal smoking during pregnancy and risk of cryptorchidism: a systematic review and meta-analysis. Eur. J. Pediatr. 178, 287–297 (2019). https://doi.org/10.1007/s00431-018-3293-9CrossRefPubMed

86.

A. Hackshaw, C. Rodeck, S. Boniface, Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls. Hum. Reprod. Update. 17, 589–604 (2011). https://doi.org/10.1093/humupd/dmr022CrossRefPubMedPubMedCentral

87.

V. Pergialiotis, P. Kotrogianni, E. Christopoulos-Timogiannakis, D. Koutaki, G. Daskalakis, N. Papantoniou, Bisphenol A and adverse pregnancy outcomes: a systematic review of the literature. J. Matern.-Fetal Neonatal Med. 31, 3320–3327 (2018). https://doi.org/10.1080/14767058.2017.1368076CrossRefPubMed

88.

K.L. Bruner-Tran, T. Ding, K.B. Yeoman, A. Archibong, J.A. Arosh, K.G. Osteen, Developmental Exposure of Mice to Dioxin Promotes Transgenerational Testicular Inflammation and an Increased Risk of Preterm Birth in Unexposed Mating Partners. PLOS ONE. 9, e105084 (2014). https://doi.org/10.1371/journal.pone.0105084CrossRefPubMedPubMedCentral

89.

A. Wautier, M. Tournaire, E. Devouche, S. Epelboin, J.-L. Pouly, A. Levadou. Genital tract and reproductive characteristics in daughters of women and men prenatally exposed to diethylstilbestrol (DES). Therapies. (2019). https://doi.org/10.1016/j.therap.2019.10.004

Titel: Environmental factors affecting pregnancy outcomes
verfasst von: Anastasia-Konstantina Sakali
Maria Papagianni
Alexandra Bargiota
Aleksandra Rasic-Markovic
Djuro Macut
George Mastorakos
Publikationsdatum: 02.02.2023
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 3/2023
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-023-03307-9

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Erhöhte Mortalität bei postpartalem Brustkrebs

07.05.2024 Mammakarzinom Nachrichten

Auch für Trägerinnen von BRCA-Varianten gilt: Erkranken sie fünf bis zehn Jahre nach der letzten Schwangerschaft an Brustkrebs, ist das Sterberisiko besonders hoch.

Hypertherme Chemotherapie bietet Chance auf Blasenerhalt

07.05.2024 Harnblasenkarzinom Nachrichten

Eine hypertherme intravesikale Chemotherapie mit Mitomycin kann für Patienten mit hochriskantem nicht muskelinvasivem Blasenkrebs eine Alternative zur radikalen Zystektomie darstellen. Kölner Urologen berichten über ihre Erfahrungen.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Vorhofflimmern bei Jüngeren gefährlicher als gedacht

06.05.2024 Vorhofflimmern Nachrichten

Immer mehr jüngere Menschen leiden unter Vorhofflimmern. Betroffene unter 65 Jahren haben viele Risikofaktoren und ein signifikant erhöhtes Sterberisiko verglichen mit Gleichaltrigen ohne die Erkrankung.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Bildnachweise

Die Leitlinien für Ärztinnen und Ärzte, Digitale Mammographien links in kraniokaudaler Projektion./© Weigel, S. et al. / all rights reserved Springer Medizin Verlag GmbH, Operation bei Blasenkrebs/© anistidesign / Fotolia, Medizinische Fachangestellte sitzt erschöpft auf der Treppe/© Courtney Haas / peopleimages.com /stock.adobe.com (Symbolbild mit Fotomodell), Mann wird von Ärztin untersucht/© Tashi-Delek, Getty Images, iStock (Symbolbild mit Fotomodellen)

Springer Medizin

Abstract

Introduction

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2023

The 5th edition of WHO classification of tumors of endocrine organs: changes in the diagnosis of follicular-derived thyroid carcinoma

Low plasma glucose results in non-diabetic adults referred from primary care are not associated with morbidity, mortality, or underlying endogenous hypoglycemic disorders

Patients undergoing endocrine consultation and first diagnosis of nodular disease: Indications of thyroid ultrasound and completeness of ultrasound reports

Is radioiodine ablation with 1.1 GBq (30 mCi) 131I necessary in low-risk thyroid cancer patients? Results from a long-term follow-up prospective study

A tribute to Ernest L. Mazzaferri, MD and the lasting impact that he had on thyroid cancer care ten years after his death