Erschienen in:
01.09.2021 | Inflammatory Bowel Disease (R Cohan, Section Editor)
Epidemiology of Colorectal Cancer in Inflammatory Bowel Disease – the Evolving Landscape
verfasst von:
Elyse A. Linson, Stephen B. Hanauer
Erschienen in:
Current Gastroenterology Reports
|
Ausgabe 9/2021
Einloggen, um Zugang zu erhalten
Abstract
Purpose of Review
To update changes in the epidemiology of colorectal cancer in patients with ulcerative colitis and Crohn’s disease over the past decades.
Recent Findings
Since the mid twentieth century, studies have found that the incidence of colorectal cancer in patients with IBD has been greater than that of the general population, especially for patients with a family history of colorectal cancer, a diagnosis of primary sclerosing cholangitis, and/or pancolitis. While Crohn’s disease and ulcerative colitis are still associated with a risk of colorectal cancer, current treatment approaches and surveillance measures have markedly reduced the risk according to population-based cohort studies such that the risk is now more comparable to that of the general population.
Summary
It is predicted that by 2025, more than two million patients will be living with inflammatory bowel disease in the United States. As advanced treatment options become available to achieve histologic remissions and as surveillance techniques to detect neoplasia improve, guidelines for surveillance will continue to evolve.