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Current Treatment Options in Oncology

Erschienen in:

01.01.2020 | Skin Cancer (T Ito, Section Editor)

Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies

verfasst von: Priscila Oliveira de Lima, Shannon Joseph, Benedict Panizza, Fiona Simpson

Erschienen in: Current Treatment Options in Oncology | Ausgabe 1/2020

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Opinion statement

Recent studies have evidenced the potential of combining anti-EGFR therapies with anti-PD-1/PD-L1 checkpoint therapies. Both anti-EGFR and anti-PD-1/PD-L1 have been separately tested in the treatment of cutaneous SCC (cSCC). Here, we review recent data on EGFR in the context of cancer progression, as a prognostic and as a therapeutic target in cSCC. Anti-EGFR/checkpoint immunotherapy and other combination therapy approaches are discussed. With the advent of immunotherapy, EGFR is still a valid cSCC target.

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Titel: Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies
verfasst von: Priscila Oliveira de Lima
Shannon Joseph
Benedict Panizza
Fiona Simpson
Publikationsdatum: 01.01.2020
Verlag: Springer US
Erschienen in: Current Treatment Options in Oncology / Ausgabe 1/2020
Print ISSN: 1527-2729
Elektronische ISSN: 1534-6277
DOI: https://doi.org/10.1007/s11864-019-0697-3

Springer Medizin

Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies

Opinion statement

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie

Springer Medizin

Opinion statement

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