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Erschienen in: Supportive Care in Cancer 2/2015

01.02.2015 | Original Article

Fertility as a priority among at-risk adolescent males newly diagnosed with cancer and their parents

verfasst von: James L. Klosky, Jessica L. Simmons, Kathryn M. Russell, Rebecca H. Foster, Gina M. Sabbatini, Kristin E. Canavera, Jason R. Hodges, Leslie R. Schover, Michael J. McDermott

Erschienen in: Supportive Care in Cancer | Ausgabe 2/2015

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Abstract

Purpose

Infertility is a frequent consequence of cancer therapy and is often associated with psychological distress. Although adult survivors prioritize fertility and parenthood, this issue remains unexplored among adolescent males. This study examined future fertility as a priority (relative to other life goals) at time of diagnosis for at-risk adolescents and their parents.

Methods

Newly diagnosed adolescent males (n = 96; age = 13.0–21.9 years) at increased risk for infertility secondary to cancer treatment prioritized eight life goals: to have school/work success, children, friends, wealth, health, a nice home, faith, and a romantic relationship. Patients’ parents (fathers, n = 30; mothers, n = 61) rank-ordered the same priorities for their children.

Results

“Having children” was ranked as a “top 3” life goal among 43.8 % of adolescents, 36.7 % of fathers, and 21.3 % of mothers. Fertility ranked third among adolescents, fourth among fathers, and fifth among mothers. Future health was ranked the top priority across groups, distinct from all other goals (ps < 0.001), and fertility ranked higher than home ownership and wealth for all groups (ps < 0.001). For adolescents, low/moderate fertility risk perception was associated with higher fertility rankings than no/high risk perceptions (p = 0.01).

Conclusions

Good health is the most important life goal among adolescents newly diagnosed with cancer and their parents. In this relatively small sample, adolescents prioritized fertility as a top goal, parents also rated fertility as being more important than home ownership and financial wealth. Health care providers should communicate fertility risk and preservation options at diagnosis and facilitate timely discussion among families, who may differ in prioritization of future fertility.
Literatur
7.
Zurück zum Zitat Bleyer A, O’Leary M, Barr R et al (2006) Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER Incidence and Survival: 1975–2000. National Cancer Institute, Bethesda, MD, NIH Pub. No. 06–5767 Bleyer A, O’Leary M, Barr R et al (2006) Cancer epidemiology in older adolescents and young adults 15 to 29 years of age, including SEER Incidence and Survival: 1975–2000. National Cancer Institute, Bethesda, MD, NIH Pub. No. 06–5767
12.
Zurück zum Zitat Burns KC, Boudreau C, Panepinto JA (2006) Attitudes regarding fertility preservation in female adolescent cancer patients. J Pediatr Hematol Oncol 28:350–354CrossRefPubMed Burns KC, Boudreau C, Panepinto JA (2006) Attitudes regarding fertility preservation in female adolescent cancer patients. J Pediatr Hematol Oncol 28:350–354CrossRefPubMed
13.
14.
Zurück zum Zitat Achille MA, Rosberger Z, Robitaille R et al (2006) Facilitators and obstacles to sperm banking in young men receiving gonadotoxic chemotherapy for cancer: the perspective of survivors and health care professionals. Hum Reprod 21:3206–3216. doi:10.1093/humrep/del307 CrossRefPubMed Achille MA, Rosberger Z, Robitaille R et al (2006) Facilitators and obstacles to sperm banking in young men receiving gonadotoxic chemotherapy for cancer: the perspective of survivors and health care professionals. Hum Reprod 21:3206–3216. doi:10.​1093/​humrep/​del307 CrossRefPubMed
15.
Zurück zum Zitat Ginsberg JP, Ogle SK, Tuchman LK et al (2008) Sperm banking for adolescent and young adult cancer patients: sperm quality, patient, and parent perspectives. Pediatr Blood Cancer 50:594–598. doi:10.1002/pbc.21257 CrossRefPubMed Ginsberg JP, Ogle SK, Tuchman LK et al (2008) Sperm banking for adolescent and young adult cancer patients: sperm quality, patient, and parent perspectives. Pediatr Blood Cancer 50:594–598. doi:10.​1002/​pbc.​21257 CrossRefPubMed
19.
21.
28.
29.
30.
Zurück zum Zitat Simmons JL, Russell KM, Canavera KE et al (2013) Discrepancies in fertility risk perceptions and communication among providers and adolescents newly diagnosed with cancer. Presented at The Society of Pediatric Psychology’s National Conference on Child Health Psychology, New Orleans, LA, 11–13 April 2013 Simmons JL, Russell KM, Canavera KE et al (2013) Discrepancies in fertility risk perceptions and communication among providers and adolescents newly diagnosed with cancer. Presented at The Society of Pediatric Psychology’s National Conference on Child Health Psychology, New Orleans, LA, 11–13 April 2013
31.
Zurück zum Zitat Canavera KE, Russell KM, Simmons JL, et al (2013) Underestimation of fertility risk among families newly diagnosed with adolescent cancer. Presented at the American Psychological Association Annual Convention, Honolulu, HI, July 31-August 4 2013 Canavera KE, Russell KM, Simmons JL, et al (2013) Underestimation of fertility risk among families newly diagnosed with adolescent cancer. Presented at the American Psychological Association Annual Convention, Honolulu, HI, July 31-August 4 2013
32.
Zurück zum Zitat Loren AW, Mangu, PB, Beck, LN, et al (2013) Fertility preservation in patients with cancer: American Society of Clinical Oncology Guideline update [published online ahead of print May 28, 2013]. J Clin Oncol, doi: 10.1200/JCO.2013.49.2678 Loren AW, Mangu, PB, Beck, LN, et al (2013) Fertility preservation in patients with cancer: American Society of Clinical Oncology Guideline update [published online ahead of print May 28, 2013]. J Clin Oncol, doi: 10.1200/JCO.2013.49.2678
Metadaten
Titel
Fertility as a priority among at-risk adolescent males newly diagnosed with cancer and their parents
verfasst von
James L. Klosky
Jessica L. Simmons
Kathryn M. Russell
Rebecca H. Foster
Gina M. Sabbatini
Kristin E. Canavera
Jason R. Hodges
Leslie R. Schover
Michael J. McDermott
Publikationsdatum
01.02.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 2/2015
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-014-2366-1

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